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Featured Lake City Resorts & Hotels with Spas
Best Western Plus Lake City
350 SW Florida Gateway Dr, Lake City, FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Baymont by Wyndham Lake City
3598 W Us Highway 90, Lake City, FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Comfort Suites Lake City
3690 W Us Highway 90, Lake City, FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Econo Lodge Live Oak
6811 N Us 129 & I 10, Live Oak, FL
Fully refundableReserve now, pay when you stay
Stay at this motel in Live Oak. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Suwannee County Historical Museum and First Federal Sportsplex ...
Fairfield Inn & Suites Lake City
538 Sw Corporate Dr, Lake City, FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hampton Inn & Suites Lake City
450 SW Florida Gateway Drive, Lake City, FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn & Suites Lake City, an IHG Hotel
213 Sw Commerce Dr, Lake City, FL
Fully refundable
Stay at this 3-star business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
Top Points of Interests in Lake City
- Hotels near North Florida Speedway
- Hotels near Lake City Mall
- Hotels near Southside Sports Complex
- Hotels near Columbia County Courthouse
- Hotels near Lake City Columbia County Historical Museum
- Hotels near Lake City Veterans Affairs Medical Center
- Hotels near Southside Recreation Complex
- Hotels near Florida Department of Transportation
- Hotels near Pine Grove Baptist Church
- Hotels near Epiphany Catholic Church
- Hotels near The Country Club At Lake City
- Hotels near Lake DeSoto Farmers Market
- Hotels near Ginnie Spring
- Hotels near Spirit of the Suwannee Music Park
- Hotels near Sante Fe College
- Hotels near Ichetucknee Springs State Park
- Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park
- Hotels near Okefenokee National Wildlife Refuge
- Hotels near O'Leno State Park
- Hotels near Ichetucknee River
Cities near Lake City
- Gainesville Hotels (41.62 mi)
- Jasper Hotels (29.22 mi)
- Live Oak Hotels (21.81 mi)
- Alachua Hotels (28.67 mi)
- Gulf Coast Hotels (668.16 mi)
- MacClenny Hotels (32.17 mi)
- Starke Hotels (35.9 mi)
- High Springs Hotels (25.18 mi)
- Newberry Hotels (37.57 mi)
- Southeastern United States Hotels (199.27 mi)
- Old Town Hotels (45.49 mi)
- Fort White Hotels (18.92 mi)
- Branford Hotels (23.48 mi)
- Central West Coast Florida Hotels (78.67 mi)
- Northern Florida Hotels (71 mi)
- Mayo Hotels (33.35 mi)
- White Springs Hotels (12.02 mi)
- Southeast Georgia Hotels (119.33 mi)
- Trenton Hotels (41.21 mi)
- North Central Florida Hotels (35.39 mi)
Car Rentals Near Lake City
- Car rentals in Gainesville
- Car rentals in Jasper
- Car rentals in Live Oak
- Car rentals in Alachua
- Car rentals in Gulf Coast
- Car rentals in MacClenny
- Car rentals in Starke
- Car rentals in High Springs
- Car rentals in Newberry
- Car rentals in Southeastern United States
- Car rentals in Old Town
- Car rentals in Fort White
- Car rentals in Branford
- Car rentals in Central West Coast Florida
- Car rentals in Northern Florida
- Car rentals in Mayo
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in Lake City
- Days Inn by Wyndham Lake City I-75
- Best Western Plus Lake City
- Knights Inn Lake City
- Baymont by Wyndham Lake City
- Americas Best Value Inn Lake City
- Comfort Suites Lake City
- Hampton Inn & Suites Lake City
- Days Inn by Wyndham Lake City I-10
- Super 8 by Wyndham Lake City
- Rodeway Inn Lake City I-75
- Holiday Inn & Suites Lake City, an IHG Hotel