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Days Inn by Wyndham Gainesville University I-75

Days Inn by Wyndham Gainesville University I-75

2.5 out of 5
920 Nw 69th Ter Gainesville FL
  • 29 min drive from Santa Fe River
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (1,016 reviews)
Close to the highway and restaurants

Reviewed on May 11, 2026

Days Inn by Wyndham Gainesville University I-75
La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville

3 out of 5
908 NW 69 Terrace Gainesville FL
  • 29 min drive from Santa Fe River
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,223 reviews)
Very spacious and clean rooms. Beds were comfortable. Breakfast had a lot of options. Gym was nicely equipped. Staff was friendly.

Reviewed on May 12, 2026

La Quinta by Wyndham Gainesville
Best Western Gateway Grand

Best Western Gateway Grand

3 out of 5
4200 NW 97th Blvd Gainesville FL
  • 24 min drive from Santa Fe River
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.6/10 Excellent! (1,472 reviews)
Vastly overpriced for experience, but UF graduation traffic lets them get away with it

Reviewed on May 11, 2026

Best Western Gateway Grand
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE Lake City FL
  • 58 min drive from Santa Fe River
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,107 reviews)
Nice hotel, nice price - recommend.

Reviewed on May 11, 2026

La Quinta Inn & Suite by Wyndham Lake City
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

2 out of 5
1699 NE Co Rd 337 High Springs FL
  • 12 min drive from Santa Fe River
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ginnie Spring and Ruth B. Kirby Gilchrist Blue Springs ...
10/10 Exceptional! (208 reviews)
de verdad q muy cómodo algo diferente me gustó muchísimo

Reviewed on May 11, 2026

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 out of 5
16367 NW 167TH BLVD Alachua FL
  • 5 min drive from Santa Fe River
Book a stay at this business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,011 reviews)
N/A

Reviewed on May 10, 2026

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

2 out of 5
3835 West US Highway 90 Lake City FL
  • 57 min drive from Santa Fe River
Stay at this motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.6/10 Excellent! (1,022 reviews)
The staff was very nice and polite and it's very simple to get in.

Reviewed on May 11, 2026

Americas Best Value Inn Lake City
Comfort Suites Lake City

Comfort Suites Lake City

2.5 out of 5
3690 W Us Highway 90 Lake City FL
  • 57 min drive from Santa Fe River
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,010 reviews)
No beach access. Front of hotel under construction- you have to go thru a small plywood area to get inside. No parking and the hotel smells like mold. Nothing like the pictures online. Avoid at all costs. Are son’s asthma is acting up because of how bad the hotel is. So upset that Expedia had this ...

Reviewed on May 9, 2026

Comfort Suites Lake City
Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

2 out of 5
3340 W US Highway 90 Lake City FL
  • 57 min drive from Santa Fe River
Stay at this motel in Lake City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Regal UA Cinema 90 and Lake City Mall are located ...
7.8/10 Good! (166 reviews)
GOOD STOP FOR ONE NIGHT IF BREAKING UP TRAVEL TIME.

Reviewed on May 11, 2026

Motel 6 – Lake City, Fl – Medical Center
Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area

2.5 out of 5
15960 NW US Highway 441 Alachua FL
  • 6 min drive from Santa Fe River
Book a stay at this business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,015 reviews)
It was just a one night stay and didn't get to take advantage of the breakfast. The room was clean and the room for the price was not bad. The bathroom though was very outdated with yellow and pink tiles and the sink faucet old and not working properly.

Reviewed on May 8, 2026

Quality Inn Alachua - Gainesville Area
Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

3 out of 5
3004 West US HWY 90 Lake City FL
  • 57 min drive from Santa Fe River
Book a stay at this business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Regal UA Cinema 90 and ...
9.4/10 Exceptional! (250 reviews)
Clean hotel, nice room, good value.

Reviewed on May 9, 2026

Courtyard By Marriott Lake City
Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr Lake City FL
  • 57 min drive from Santa Fe River
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,062 reviews)
Quiet Clean &comfortable

Reviewed on May 11, 2026

Best Western Plus Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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