Hotels Near
Main Street Fort Pierce

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Featured Main Street Fort Pierce Hotels

At Home Inn

At Home Inn

2.5 out of 5
7025 Okeechobee Road Fort Pierce FL
Fully refundableReserve now, pay when you stay
Stay at this motel in Fort Pierce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,029 reviews)
Just a great place to stay for a night that won’t hurt the pockets

Reviewed on Jan 24, 2026

At Home Inn
Vero Beach Inn & Suites I-95

Vero Beach Inn & Suites I-95

3 out of 5
8797 20th St Vero Beach FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Vero Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,406 reviews)
Room was clean. Decent area right off freeway.

Reviewed on Jan 27, 2026

Vero Beach Inn & Suites I-95
The Lucie

The Lucie

3 out of 5
10978 S Ocean Dr Jensen Beach FL
Fully refundableReserve now, pay when you stay
Book a stay at this beach hotel in Jensen Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the helpful staff in our reviews. ...
8.8/10 Excellent! (1,014 reviews)
EVERYONE and EVERYTHING was fantastic…welcoming front desk at checkin/out. Our oceanfront w/balcony room was very comfortable & pristine (clean). Housekeeping was wonderful and the staffs at the breakfast Bistro and pool tiki hut were great.

Reviewed on Jan 28, 2026

The Lucie
voco Sandpiper All Inclusive Resort by IHG

voco Sandpiper All Inclusive Resort by IHG

3.5 out of 5
4500 SE Pine Valley Street Port Saint Lucie FL
Fully refundable
Book a stay at this beach resort in Port Saint Lucie. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Popular attractions The Saints at Port St. Lucie Golf ...
10/10 Exceptional! (1 review)
Everyone went above and beyond Rooms are spacious and the meals are delicious 😋

Reviewed on Jan 20, 2026

voco Sandpiper All Inclusive Resort by IHG
Costa d'Este Beach Resort and Spa

Costa d'Este Beach Resort and Spa

4 out of 5
3244 Ocean Drive Vero Beach FL
Fully refundableReserve now, pay when you stay
Book a stay at this beach hotel in Vero Beach. Enjoy a full-service spa, a beach locale, and 2 bars/lounges. Our guests praise the restaurant and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
gorgeous room and so much appreciated the upgrade

Reviewed on Jan 21, 2026

Costa d'Este Beach Resort and Spa
Hutchinson Island Hotel

Hutchinson Island Hotel

2.5 out of 5
1230 Seaway Drive Fort Pierce FL
Fully refundableReserve now, pay when you stay
Book a stay at this beach hotel in Fort Pierce. Enjoy free breakfast, free WiFi, and a private beach. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,373 reviews)
This is my 4th time staying at this hotel due to being on the water with a private dock and beach. Location of hotel is great too, with quick access to many great food spots. The room was clean and parking was provided. The reason I'm giving it 4 starts because it needs a little bit of updating. ...

Reviewed on Jan 27, 2026

Hutchinson Island Hotel
Ocean Breeze Inn Vero Beach

Ocean Breeze Inn Vero Beach

3.5 out of 5
3384 Ocean Dr Vero Beach FL
Fully refundableReserve now, pay when you stay
Book a stay at this beach hotel in Vero Beach. Enjoy free WiFi, free parking, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,120 reviews)
Loved it! Watched the sunrise every morning from our patio, easy and short walk right out to the beach and many great walkable options for breakfast lunch and dinner!

Reviewed on Jan 29, 2026

Ocean Breeze Inn Vero Beach
Marriott Hutchinson Island Beach Resort, Golf & Marina

Marriott Hutchinson Island Beach Resort, Golf & Marina

3.5 out of 5
555 NE Ocean Boulevard Stuart FL
Book a stay at this beach hotel in Stuart. Enjoy 3 outdoor pools, 3 restaurants, and a beach locale. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (422 reviews)
Very clean and amazing staffing

Reviewed on Jan 18, 2026

Marriott Hutchinson Island Beach Resort, Golf & Marina
Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa

4 out of 5
3793 NE Ocean Boulevard Jensen Beach FL
Fully refundableReserve now, pay when you stay
Book a stay at this beach resort in Jensen Beach. Enjoy free parking, 2 outdoor pools, and a beach locale. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,000 reviews)
All of the above and more. We have resided in FL for 37 years and never been to your hotel. You far exceeded our expectations! Congrats and yes we hope you will host us again!!

Reviewed on Jan 26, 2026

Hutchinson Shores Resort & Spa
WoodSpring Suites Port St. Lucie

WoodSpring Suites Port St. Lucie

2.5 out of 5
11600 SW Village Parkway Port Saint Lucie FL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Port Saint Lucie. Enjoy free parking, a 24-hour fitness center, and laundry facilities. Popular attractions Woodlands Trails Park and Whispering ...
8/10 Very Good! (344 reviews)
Staff was great, hotel was clean, but some guests were loud.

Reviewed on Jan 19, 2026

WoodSpring Suites Port St. Lucie
Best Western Downtown Stuart

Best Western Downtown Stuart

3 out of 5
1209 SE Federal Hwy Stuart FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Stuart. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,000 reviews)
Everything was great, good breakfast too

Reviewed on Jan 24, 2026

Best Western Downtown Stuart
The Royal Inn Beach Hotel Hutchinson Island

The Royal Inn Beach Hotel Hutchinson Island

2.5 out of 5
222 Hernando Street Fort Pierce FL
Fully refundableReserve now, pay when you stay
Book a stay at this beach hotel in Fort Pierce. Enjoy free WiFi, free parking, and 5 beach bars. Our guests praise the helpful staff and the clean rooms in our ...
7/10 Good! (999 reviews)
Thank you

Reviewed on Jan 27, 2026

The Royal Inn Beach Hotel Hutchinson Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Main Street Fort Pierce

Fort Pierce is a city that has a lot going on, but you have your sights set on Main Street Fort Pierce. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Main Street Fort Pierce has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Main Street Fort Pierce hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Fort Pierce so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Main Street Fort Pierce underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Main Street Fort Pierce city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Main Street Fort Pierce cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Main Street Fort Pierce at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $90
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Main Street Fort Pierce hotel you want, book it, and never look back. Because your great escape is ahead of you.