Search Deals onMayesville Vacation Packages
Mayesville Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.
Studio 6 Florence , SC
Price was $664, price is now $648 per person
$648
per person
Nov 20 - Nov 22
just found
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Stay at this motel in Florence. Enjoy free WiFi, a 24-hour front desk, and a snack bar/deli. Popular attractions Dr. Eddie Floyd Tennis Center and CarolinaBank Field are located nearby.
The Inn at the Crossroads
Price was $822, price is now $771 per person
$771
per person
Nov 20 - Nov 22
just found
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Lynches Lake Historical Society and The Bean Market are located nearby.
Hyatt Place Florence Downtown
Price was $798, price is now $775 per person
$775
per person
Nov 20 - Nov 22
just found
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Florence County Museum and FMU Performing Arts Center are located nearby.
Very clean, nice staff and good breakfast
Reviewed on Sep 21, 2026
TownePlace Suites by Marriott Florence
Price was $753, price is now $732 per person
$732
per person
Nov 20 - Nov 22
just found
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Florence Veterans Park and Magnolia Mall are located nearby.
Many special touches were evident from the entrance to everything in my room, through breakfast and departure. The desk attendant recommended a wonderful Mexican restaurant only 3 minutes away. Absolutely amazing service!
Reviewed on Sep 22, 2026
The Mantissa Hotel
Price was $820, price is now $801 per person
$801
per person
Nov 20 - Nov 22
just found
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Hartsville Museum and Center Theatre are located nearby.
Super 8 by Wyndham Florence SC I-95 North / Hwy 76
Price was $672, price is now $658 per person
$658
per person
Nov 20 - Nov 22
just found
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Stay at this motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Florence Rail Trail and Regal Swamp Fox are located nearby.
Comfort Inn & Suites Florence Center Area
Price was $719, price is now $709 per person
$709
per person
Nov 20 - Nov 22
just found
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Florence Veterans Park and Magnolia Mall are located nearby.
Staff very helpful. Rooms need updating- a little musty - Bed was clean and. Comfy. Breakfast was ok - overall you get what you pay for
Reviewed on Sep 25, 2026
Motel 6 Florence, SC
Price was $660, price is now $651 per person
$651
per person
Nov 20 - Nov 22
just found
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Stay at this motel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Dr. Eddie Floyd Tennis Center and CarolinaBank Field are located nearby.
Pass by this hotel!
Reviewed on Sep 24, 2026
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Wed, Oct 28 - Wed, Nov 4
LGA
LaGuardia
FLO
Florence Regional
$388 Roundtrip, found 15 hours ago
$388
Roundtrip
found 15 hours ago
Thu, Jan 21 - Thu, Jan 28
DFW
Dallas-Fort Worth Intl.
FLO
Florence Regional
$431 Roundtrip, found 1 day ago
$431
Roundtrip
found 1 day ago
Tue, Dec 22 - Wed, Jan 6
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$537 Roundtrip, found 1 day ago
$537
Roundtrip
found 1 day ago
Sat, Oct 24 - Sun, Oct 25
BOS
Logan Intl.
FLO
Florence Regional
$555 Roundtrip, found 3 days ago
$555
Roundtrip
found 3 days ago
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