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Mayesville

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Mayesville Flights as Low as $289

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Cheap Flights to Mayesville

Fall in love at first flight with your vacation to Mayesville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mayesville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Mayesville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Mayesville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mayesville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the FLO airport.

What is the cheapest month to fly to Mayesville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mayesville are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Mayesville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Mayesville.

What airport is best to fly into Mayesville?

When you’re planning your trip to Mayesville, convenience is the name of the game. Luckily, Mayesville Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Mayesville must-do list.

How much are flights to Mayesville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mayesville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $289, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Mayesville?

The trick to saving a stack of cash on your flight to Mayesville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $289 right now, why wait?

Mayesville Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$288

Last Minute Hotel Deals in Mayesville

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

2.5 out of 5
2816 Paxville Highway Manning SC
Book a stay at this business-friendly hotel in Manning. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,006 reviews)
Nice stay.!!

Reviewed on Apr 10, 2026

SureStay Hotel by Best Western Manning
Woodspring Suites Sumter Near Shaw Afb

Woodspring Suites Sumter Near Shaw Afb

2.5 out of 5
2715 Broad Street Sumter SC
Stay at this hotel in Sumter. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Sumter Mall and Palmetto Park are located nearby.
8.2/10 Very Good! (192 reviews)
I tried to add a person to the hotel room for a week, and the property still gave the room away to someone else. It was nothing but a hassle; I will never book there again.

Reviewed on Apr 6, 2026

Woodspring Suites Sumter Near Shaw Afb
Hyatt Place Sumter / Downtown

Hyatt Place Sumter / Downtown

3 out of 5
18 N Main St Sumter SC
Book a stay at this business-friendly hotel in Sumter. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (914 reviews)
Staff is nice except for Jason who was rude and not helpful when I informed him that our hotel room door was open when we returned to the room that evening. I probably won't stay here again due to security issues. I had the Do Not Disturb on the door and they still made the beds and left the door ...

Reviewed on Apr 7, 2026

Hyatt Place Sumter / Downtown
Red Roof Inn Sumter

Red Roof Inn Sumter

2 out of 5
1211 Camden Highway Sumter SC
Stay at this hotel in Sumter. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Sumter Mall and Palmetto Park are located nearby.
6.8/10 (292 reviews)
Hard location to turn into

Reviewed on Mar 29, 2026

Red Roof Inn Sumter
Hampton Inn Manning

Hampton Inn Manning

2.5 out of 5
2822 Paxville Hwy Manning SC
Book a stay at this business-friendly hotel in Manning. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,000 reviews)
Keep up the good service

Reviewed on Mar 31, 2026

Hampton Inn Manning
Baymont by Wyndham Manning

Baymont by Wyndham Manning

2.5 out of 5
2284 Raccoon Road Manning SC
Stay at this hotel in Manning. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews.
6.8/10 (1,001 reviews)
Clean Nice bed Good shower

Reviewed on Mar 28, 2026

Baymont by Wyndham Manning
Spark by Hilton Sumter

Spark by Hilton Sumter

2.5 out of 5
2491 Broad St Sumter SC
Stay at this hotel in Sumter. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Sumter ...
7.2/10 Good! (30 reviews)
There was poop smeared on the wall in the bathroom and there were roaches in the room. I have never been so disturbed and disgusted with a hotel room in my life. Safe to say I will never stay there again.

Reviewed on Apr 4, 2026

Spark by Hilton Sumter
1912 Bed and Breakfast

1912 Bed and Breakfast

3.5 out of 5
24 Warren St Sumter SC
Book a stay at this business-friendly B&B in Sumter. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
10/10 Exceptional! (299 reviews)
READ ME: For me and my wife, this was an extremely pleasant discovery and experience. We like different, so while this place can be made workable (which I will tell you how to do), keep in mind that this might not be your cup of tea on a business trip where stardardization may have been the better ...

Reviewed on Apr 1, 2026

1912 Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.