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Mayesville

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Mayesville Flights as Low as $328

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Thu, May 1 - Mon, May 5
MCI
Kansas City Intl.
FLO
Florence Regional
$328 Roundtrip, found 1 day ago
$328
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, May 1 from Kansas City Intl. to Florence Regional, returning Mon, May 5, priced at $328 found 1 day ago
American Airlines
Tue, Apr 29 - Mon, May 5
MCI
Kansas City Intl.
FLO
Florence Regional
$330 Roundtrip, found 1 day ago
$330
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Apr 29 from Kansas City Intl. to Florence Regional, returning Mon, May 5, priced at $330 found 1 day ago
American Airlines
Mon, May 5 - Tue, May 6
MCI
Kansas City Intl.
FLO
Florence Regional
$331 Roundtrip, found 1 day ago
$331
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, May 5 from Kansas City Intl. to Florence Regional, returning Tue, May 6, priced at $331 found 1 day ago
American Airlines
Thu, May 1 - Sat, May 3
MCI
Kansas City Intl.
FLO
Florence Regional
$348 Roundtrip, found 1 day ago
$348
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, May 1 from Kansas City Intl. to Florence Regional, returning Sat, May 3, priced at $348 found 1 day ago
American Airlines
Tue, Apr 29 - Sat, May 3
MCI
Kansas City Intl.
FLO
Florence Regional
$350 Roundtrip, found 1 day ago
$350
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Apr 29 from Kansas City Intl. to Florence Regional, returning Sat, May 3, priced at $350 found 1 day ago
American Airlines
Fri, May 2 - Mon, May 5
MCI
Kansas City Intl.
FLO
Florence Regional
$358 Roundtrip, found 1 day ago
$358
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 2 from Kansas City Intl. to Florence Regional, returning Mon, May 5, priced at $358 found 1 day ago
American Airlines
Fri, May 2 - Mon, May 5
STL
Lambert-St. Louis Intl.
FLO
Florence Regional
$360 Roundtrip, found 1 day ago
$360
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 2 from Lambert-St. Louis Intl. to Florence Regional, returning Mon, May 5, priced at $360 found 1 day ago
American Airlines
Fri, May 2 - Mon, May 5
MCI
Kansas City Intl.
FLO
Florence Regional
$367 Roundtrip, found 1 day ago
$367
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 2 from Kansas City Intl. to Florence Regional, returning Mon, May 5, priced at $367 found 1 day ago
American Airlines
Thu, May 1 - Sun, May 4
STL
Lambert-St. Louis Intl.
FLO
Florence Regional
$368 Roundtrip, found 1 day ago
$368
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, May 1 from Lambert-St. Louis Intl. to Florence Regional, returning Sun, May 4, priced at $368 found 1 day ago
American Airlines
Fri, May 2 - Mon, May 5
STL
Lambert-St. Louis Intl.
FLO
Florence Regional
$370 Roundtrip, found 1 day ago
$370
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 2 from Lambert-St. Louis Intl. to Florence Regional, returning Mon, May 5, priced at $370 found 1 day ago
American Airlines
Thu, May 1 - Sun, May 4
STL
Lambert-St. Louis Intl.
FLO
Florence Regional
$378 Roundtrip, found 1 day ago
$378
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, May 1 from Lambert-St. Louis Intl. to Florence Regional, returning Sun, May 4, priced at $378 found 1 day ago
American Airlines
Fri, May 2 - Mon, May 5
STL
Lambert-St. Louis Intl.
FLO
Florence Regional
$380 Roundtrip, found 1 day ago
$380
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 2 from Lambert-St. Louis Intl. to Florence Regional, returning Mon, May 5, priced at $380 found 1 day ago
American Airlines
Thu, May 1 - Sun, May 4
STL
Lambert-St. Louis Intl.
FLO
Florence Regional
$383 Roundtrip, found 1 day ago
$383
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, May 1 from Lambert-St. Louis Intl. to Florence Regional, returning Sun, May 4, priced at $383 found 1 day ago
American Airlines
Fri, May 2 - Mon, May 5
STL
Lambert-St. Louis Intl.
FLO
Florence Regional
$390 Roundtrip, found 1 day ago
$390
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 2 from Lambert-St. Louis Intl. to Florence Regional, returning Mon, May 5, priced at $390 found 1 day ago
American Airlines
Mon, Apr 28 - Thu, May 1
STL
Lambert-St. Louis Intl.
FLO
Florence Regional
$398 Roundtrip, found 1 day ago
$398
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Apr 28 from Lambert-St. Louis Intl. to Florence Regional, returning Thu, May 1, priced at $398 found 1 day ago
American Airlines
Fri, May 2 - Mon, May 5
SGF
Springfield-Branson National
FLO
Florence Regional
$470 Roundtrip, found 1 day ago
$470
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 2 from Springfield-Branson National to Florence Regional, returning Mon, May 5, priced at $470 found 1 day ago

Cheap Flights to Mayesville

Fall in love at first flight with your vacation to Mayesville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mayesville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Mayesville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Mayesville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mayesville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the FLO airport.

What is the cheapest month to fly to Mayesville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mayesville are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Mayesville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Mayesville.

What airport is best to fly into Mayesville?

When you’re planning your trip to Mayesville, convenience is the name of the game. Luckily, Mayesville Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Mayesville must-do list.

How much are flights to Mayesville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mayesville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $328, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Mayesville?

The trick to saving a stack of cash on your flight to Mayesville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $328 right now, why wait?

Mayesville Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$328

Last Minute Hotel Deals in Mayesville

Hyatt Place Sumter / Downtown
Hyatt Place Sumter / Downtown
3 out of 5
18 N Main St, Sumter, SC
The price is $119 per night from Mar 30 to Mar 31
$119
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star business-friendly hotel in Sumter. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (766 reviews)
"Ms. Loretta at the front desk was an absolute pleasure. She was very polite and courteous. She informed me of everything that I needed to know about the facility and around the facility. I will definitely be back"

Reviewed on Mar 12, 2025

Hyatt Place Sumter / Downtown
SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western Manning
2.5 out of 5
2816 Paxville Highway, Manning, SC
The price is $111 per night from Mar 16 to Mar 17
$111
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this business-friendly hotel in Manning. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,000 reviews)
"clean comfortable reasonably priced hotel to stay overnight on our way to FLorida."

Reviewed on Feb 28, 2025

SureStay Hotel by Best Western Manning
Tru by Hilton Sumter
Tru by Hilton Sumter
2.5 out of 5
2607 Broad Street, Sumter, SC
The price is $122 per night from Mar 30 to Mar 31
$122
includes taxes & fees
Mar 30 - Mar 31
Stay at this hotel in Sumter. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.8/10 Excellent! (608 reviews)
"The property is clean and modern."

Reviewed on Mar 8, 2025

Tru by Hilton Sumter
Comfort Suites Sumter
Comfort Suites Sumter
2.5 out of 5
2500 Broad St, Sumter, SC
The price is $97 per night from Mar 30 to Mar 31
$97
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Sumter. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Sumter Mall and Palmetto Park are ...
7.2/10 Good! (523 reviews)
"Enjoyed my stay. Definitely will be back"

Reviewed on Feb 25, 2025

Comfort Suites Sumter
Baymont by Wyndham Manning
Baymont by Wyndham Manning
2.5 out of 5
2284 Raccoon Road, Manning, SC
The price is $95 per night from Mar 17 to Mar 18
$95
includes taxes & fees
Mar 17 - Mar 18
Stay at this hotel in Manning. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews.
6.8/10 (1,003 reviews)
"K"

Reviewed on Mar 12, 2025

Baymont by Wyndham Manning
Sleep Inn Sumter
Sleep Inn Sumter
2.5 out of 5
2510 Broad St, Sumter, SC
The price is $84 per night from Mar 30 to Mar 31
$84
includes taxes & fees
Mar 30 - Mar 31
Stay at this hotel in Sumter. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Sumter ...
6.4/10 (570 reviews)
Nice for a few nights
"This hotel is in a great location close to lots of places to eat and shop. The facility itself is nice and clean and the employees were polite during check in. My room was pretty much clean except the toilet in my room. The toilet was visibly dirty, which I handled myself as it was very late when ..."

Reviewed on Mar 8, 2025

Sleep Inn Sumter
Americas Best Value Inn & Suites Sumter
Americas Best Value Inn & Suites Sumter
2.5 out of 5
2430 Broad Street, Sumter, SC
The price is $111 per night from Mar 16 to Mar 17
$111
includes taxes & fees
Mar 16 - Mar 17
Stay at this motel in Sumter. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Sumter Mall and Palmetto Park are located nearby.
6.6/10 (229 reviews)
"Rooms could be cleaner... But overall the stay was enjoyable..."

Reviewed on Feb 10, 2025

Americas Best Value Inn & Suites Sumter
Holiday Inn Express Sumter by IHG
Holiday Inn Express Sumter by IHG
2.5 out of 5
2490 Broad St, Sumter, SC
The price is $129 per night from Mar 23 to Mar 24
$129
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Sumter. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (645 reviews)
"The bed and pillows were comfortable. I liked the Dove bath products in the bathroom."

Reviewed on Feb 27, 2025

Holiday Inn Express Sumter by IHG
See all 73 properties in Mayesville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.