Search Cheap Flights toMayesville
Search 400 airlines and 321,000 hotels worldwide.
Stop Planning & Start Exploring
FREE 24 hour cancellation on most flights
Mayesville Flights as Low as $262
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Cheap Flights to Mayesville
Fall in love at first flight with your vacation to Mayesville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mayesville on Hotwire, and you’ll be up, up, and on a getaway in no time.
Because once the wheels are down in Mayesville, the good times start rolling. So buckle up, you’re in for a fun ride.
Frequently Asked Questions About flights to Mayesville
Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mayesville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.
So all you have to worry about is where you’re headed after the FLO airport.
What is the cheapest month to fly to Mayesville?
Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mayesville are in July, but when you book your flight on Hotwire, savings are always in season.
How many airlines fly to Mayesville?
Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Mayesville.
What airport is best to fly into Mayesville?
When you’re planning your trip to Mayesville, convenience is the name of the game. Luckily, Mayesville Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Mayesville must-do list.
How much are flights to Mayesville?
Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mayesville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $262, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.
How to get cheap flights to Mayesville?
The trick to saving a stack of cash on your flight to Mayesville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $262 right now, why wait?
Destination airport | Florence Regional |
|---|---|
Destination airport IATA code | FLO |
Roundtrip price | $261 |
Last Minute Hotel Deals in Mayesville
Woodspring Suites Sumter Near Shaw Afb
Young lady was very friendly and helpful
Reviewed on Feb 9, 2026
SureStay Hotel by Best Western Manning
Clean, modern room
Reviewed on Feb 6, 2026
Hampton Inn Manning
Nice place
Reviewed on Feb 9, 2026
Hyatt Place Sumter / Downtown
The room was very clean and spacious
Reviewed on Feb 14, 2026
Tru by Hilton Sumter
This hotel is modern, clean and in a great location. All the staff members were courteous and very helful during the snow storm. Highly recommended.
Reviewed on Feb 3, 2026
1912 Bed and Breakfast
The owners were very nice and concerned about your comfort. The rooms were very comfortable.
Reviewed on Feb 8, 2026
Holiday Inn Express Sumter by IHG
Few strands of hair in shower.
Reviewed on Feb 9, 2026
Hampton Inn Sumter
Yes
Reviewed on Feb 4, 2026
Nearby Cities
Popular Flight Routes
- Atlanta to New York
- Detroit to Las Vegas
- Dallas to Atlanta
- Dallas to Yosemite National Park
- Toronto to Edmonton
- Chicago to Tulum
- Houston to Lake Tahoe
- Chicago to Las Vegas
- Dallas to Miami
- Dallas to Lake Tahoe
- New York to Miami
- New York to Las Vegas
- Miami to Atlanta
- Minneapolis St Paul to Fort Walton Beach Destin
- Dallas to Branson
- Cleveland to Vero Beach
- Managua to Miami
- Atlanta to Boston
- Austin to Tulum
- Calgary to Vancouver