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Tonight Nov 17 - Nov 18Next weekend Nov 22 - Nov 24

Choose from 7770 Houston Hotel Deals

Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
  • 9 min drive from MD Anderson Cancer Center
The price is $112 per night from Dec 17 to Dec 18
$112
includes taxes & fees
Dec 17 - Dec 18
Stay at this 4-star aparthotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful staff in ...
8.2/10 Very Good! (3,065 reviews)
"I really enjoyed my stay at club quarters- I was alone and the staff were extremely friendly and helpful- welcoming you every time you entered or left! Looking after luggage etc. Easy to walk to the convention I attended and lots of eating places within 5-6 blocks! Room was nearby the elevator so ..."

Reviewed on Nov 15, 2024

Club Quarters Hotel Downtown, Houston
Blossom Hotel Houston
Blossom Hotel Houston
4 out of 5
7118 Bertner Ave, Houston, TX
  • 12 min walk from MD Anderson Cancer Center
The price is $183 per night from Nov 24 to Nov 25
$183
includes taxes & fees
Nov 24 - Nov 25
Stay at this 4-star spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (2,850 reviews)
"Incredible service, beautiful hotel rooms extremely accommodating service staff was professional"

Reviewed on Nov 14, 2024

Blossom Hotel Houston
The Whitehall Houston
The Whitehall Houston
4 out of 5
1700 Smith St, Houston, TX
  • 8 min drive from MD Anderson Cancer Center
The price is $149 per night from Nov 24 to Nov 25
$149
includes taxes & fees
Nov 24 - Nov 25
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,076 reviews)
"The ambiance and decor"

Reviewed on Nov 12, 2024

The Whitehall Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
5353 Westheimer Rd, Houston, TX
  • 6 min drive from MD Anderson Cancer Center
The price is $135 per night from Dec 16 to Dec 17
$135
includes taxes & fees
Dec 16 - Dec 17
Stay at this hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,561 reviews)
"Quiet location. Great view from the balcony. LOVED the cookies. Only issue I had during my stay was the linen not being clean on the bed. The staff were more than accommodating in making sure I was placed in a room equal to what was booked. We arrived late a few nights and the overnight crew showed ..."

Reviewed on Nov 16, 2024

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Holiday Inn Houston Downtown, an IHG Hotel
Holiday Inn Houston Downtown, an IHG Hotel
3 out of 5
1616 Main St, Houston, TX
  • 8 min drive from MD Anderson Cancer Center
The price is $118 per night from Dec 18 to Dec 19
$118
includes taxes & fees
Dec 18 - Dec 19
Stay at this 3-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,005 reviews)
Good place on a budget,
"Very friendly staff, great service. Good location downtown."

Reviewed on Nov 15, 2024

Holiday Inn Houston Downtown, an IHG Hotel
La Quinta Inn & Suites by Wyndham Houston Galleria Area
La Quinta Inn & Suites by Wyndham Houston Galleria Area
2.5 out of 5
1625 West Loop S, Houston, TX
  • 7 min drive from MD Anderson Cancer Center
The price is $95 per night from Nov 21 to Nov 22
$95
includes taxes & fees
Nov 21 - Nov 22
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.6/10 Good! (1,221 reviews)
"I liked this place"

Reviewed on Nov 15, 2024

La Quinta Inn & Suites by Wyndham Houston Galleria Area
C. Baldwin, Curio Collection by Hilton
C. Baldwin, Curio Collection by Hilton
4 out of 5
400 Dallas St, Houston, TX
  • 9 min drive from MD Anderson Cancer Center
The price is $214 per night from Dec 1 to Dec 2
$214
includes taxes & fees
Dec 1 - Dec 2
Stay at this hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (922 reviews)
"This property was great. Rooms are very spacious and the views are also nice. They are also pet friendly."

Reviewed on Nov 16, 2024

C. Baldwin, Curio Collection by Hilton
DoubleTree by Hilton Houston Brookhollow
DoubleTree by Hilton Houston Brookhollow
4 out of 5
12801 Northwest Fwy, Houston, TX
  • 23 min drive from MD Anderson Cancer Center
Stay at this hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the breakfast and the pool in our reviews. Popular ...
8/10 Very Good! (2,296 reviews)
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Reviewed on Jun 17, 2024

DoubleTree by Hilton Houston Brookhollow
Hyatt Regency Houston West
Hyatt Regency Houston West
3.5 out of 5
13210 Katy Fwy, Houston, TX
  • 14 min drive from MD Anderson Cancer Center
The price is $111 per night from Nov 24 to Nov 25
$111
includes taxes & fees
Nov 24 - Nov 25
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
8.4/10 Very Good! (1,007 reviews)
"Great hotel except the toilet only flushed once every 10 mins so that was frustrating but really nice hotel"

Reviewed on Nov 11, 2024

Hyatt Regency Houston West
Hilton Houston Westchase
Hilton Houston Westchase
4 out of 5
9999 Westheimer Rd, Houston, TX
  • 6 min drive from MD Anderson Cancer Center
Stay at this 4-star business-friendly hotel in Houston. Enjoy free parking, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
7.8/10 Good! (1,008 reviews)
"The area seems good, and the hotel was all good for most of the stay, but on the last night of my stay, it seems something had gotten into the bathroom sink and made a mess that seemed to be smelly. I was in a hurry on the way out and didn't report it to the staff though."

Reviewed on Nov 11, 2024

Hilton Houston Westchase
SpringHill Suites by Marriott Houston Intercontinental Arprt
SpringHill Suites by Marriott Houston Intercontinental Arprt
3 out of 5
15840 John F Kennedy Blvd, Houston, TX
  • 40 min drive from MD Anderson Cancer Center
The price is $121 per night from Dec 16 to Dec 17
$121
includes taxes & fees
Dec 16 - Dec 17
Stay at this 3-star business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,198 reviews)
"Very clean, great staff, great property for the price."

Reviewed on Nov 16, 2024

SpringHill Suites by Marriott Houston Intercontinental Arprt
Hilton Americas-Houston
Hilton Americas-Houston
4 out of 5
1600 Lamar Street, Houston, TX
  • 7 min drive from MD Anderson Cancer Center
The price is $180 per night from Nov 26 to Nov 27
$180
includes taxes & fees
Nov 26 - Nov 27
Stay at this 4-star spa hotel in Houston. Enjoy a full-service spa, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,115 reviews)
"The stay was great, rooms were clean and the staff was amazing."

Reviewed on Nov 14, 2024

Hilton Americas-Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Book Last Minute Hotel Deals in Houston

Space shuttles aren’t the only thing to take off in Houston. This is a city meant for explorers, adventures, and the ones who say “no thank you” to conventional travel plans. It’s a place where you can rocket yourself as far as space and as deep as hidden art installations below the ground.

Ready to leave the others in the dust? Good. Whether you’re hitting up one of the hotels near Johnson Space Center or somewhere downtown, it’s time to plant your flag in this Texas town.

Make Your Own Mission

  • Uncover the Underground Scene: Literally. Go below the surface to the Buffalo Bayou Park Cistern, a former underground drinking water reservoir. The massive space has since turned into a trippy art installation with a 17-second echo. Prefer a more traditional underground scene? Knock twice on the red door for access into Last Concert Café, a quirky space for live jams, or unlock the oddities at Notsouh (but can you guess the bar’s namesake?).

  • Breakfast of Champions: Expect some funny looks if you’re not shoving breakfast tacos down your gullet every morning. Different day? Different taco joint. Bring those dolla’ bills to Tacos Tierra Caliente, where the breakfast tacos are a $1 a pop, or hit up the drive-thru at El Rey Taqueria, which gets bonus points for letting you order in your PJs. Make your home base one of the hotels in Downtown Houston and map out your taco hop from there.

  • Burp the Bayou: See that red button at Buffalo Bayou Park? Go on, push it. Just do it! We dare you. Under the Preston Street bridge, there’s an art installation known as the Big Bubble. We can’t tell you where exactly the button is—finding it is half the fun. What is it about mysterious red buttons that make them so irresistible? Find out for yourself and discover what the heck it means to burp the bayou.

  • Full of Bull: You can’t do Houston right without a rodeo. And the Houston Livestock Show and Rodeo isn’t just any ol’ rodeo; it’s the largest rodeo in the world. No bull. It’s three weeks of country music, barbecue contests, livestock shows, and a whole lot of cowboy boots.

It’s hard not to go big in a place like Houston, which means you’re definitely not going home yet. You can choose from hotels near Minute Maid Park—watch for fly balls!—or Houston hotels near the airport. Pick a Hotwire Hot Rate, it’s like clicking your own red button, and you’ll score the biggest last-minute hotel deals in Houston.