Hotels Near
Texas Medical Center

Check Last Minute Texas Medical Center Hotel Deals

Tonight Jun 29 - Jun 30Next weekend Jul 4 - Jul 6

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured Texas Medical Center Hotels

Blossom Hotel Houston
Blossom Hotel Houston
4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (3,360 reviews)
"Parking prices are high for location. Reims were great, staff was great."

Reviewed on Jun 25, 2025

Blossom Hotel Houston
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,399 reviews)
"I would recommend this property."

Reviewed on Jun 26, 2025

Hilton Houston Plaza/Medical Center
Hyatt Place Houston Medical Center
Hyatt Place Houston Medical Center
3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,741 reviews)
"Stayed 2 nights, the staff was outstanding, and the breakfast was awesome with so many choices having both hot and cold choices. Each morning, there was different hot choices to choose from."

Reviewed on Jun 26, 2025

Hyatt Place Houston Medical Center
The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum District
4 out of 5
1709 DRYDEN ROAD, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
9/10 Wonderful! (1,004 reviews)
"Staff friendliness and cleanliness"

Reviewed on Jun 26, 2025

The Westin Houston Medical Center/Museum District
InterContinental Houston by IHG
InterContinental Houston by IHG
4 out of 5
6750 Main St, Houston, TX
Fully refundable
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,000 reviews)
"Great overall experience, The room 1101, at the end of the hall was great, strange barn door slider on the bathroom, not much for privacy. Other than that, everything else was great."

Reviewed on Jun 17, 2025

InterContinental Houston by IHG
DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & Suites
4 out of 5
6800 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (367 reviews)
Worth a good nights stay
"More counter space would have been better in the bathroom. Otherwise very comfortable room and very dark to sleep I"

Reviewed on Jun 23, 2025

DoubleTree by Hilton Houston Medical Center Hotel & Suites
Hyatt House Houston Medical Center
Hyatt House Houston Medical Center
3 out of 5
7329 FANNIN STREET, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (1,010 reviews)
"Amazing staff and clean room. We will be back"

Reviewed on Jun 18, 2025

Hyatt House Houston Medical Center
Hilton Garden Inn Houston Medical Center, TX
Hilton Garden Inn Houston Medical Center, TX
3 out of 5
6840 Almeda Rd, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
9.2/10 Wonderful! (870 reviews)
"Very clean and the staff was always helpful. The breakfast buffet was a good deal!"

Reviewed on Jun 28, 2025

Hilton Garden Inn Houston Medical Center, TX
Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,467 reviews)
"Great staff... hotel is close to a lot of food options."

Reviewed on Jun 27, 2025

Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
5353 Westheimer Rd, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (2,136 reviews)
"The property is in a great location near restaurants and shopping areas. I was on the 25th floor with a city view. The staff were super nice and helpful with my stay.. my issue was the room was outdated and not the cleanest. I had high expectations because it’s in the galleria but it was overall ..."

Reviewed on Jun 26, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hilton Americas-Houston
Hilton Americas-Houston
4 out of 5
1600 Lamar Street, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Houston. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,333 reviews)
"Close to several restaurants and Discovery Green. Hotel was a great stay for my business trip!"

Reviewed on Jun 26, 2025

Hilton Americas-Houston
The Whitehall Houston
The Whitehall Houston
4 out of 5
1700 Smith St, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,535 reviews)
"Which one is that it's a great staff?Beautiful city easy to get around"

Reviewed on Jun 25, 2025

The Whitehall Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Texas Medical Center

Houston is a city that has a lot going on, but you have your sights set on Texas Medical Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Texas Medical Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Texas Medical Center hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Houston so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Texas Medical Center underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Texas Medical Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Texas Medical Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Texas Medical Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Texas Medical Center hotel you want, book it, and never look back. Because your great escape is ahead of you.