Hotels Near
Texas Medical Center

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Featured Texas Medical Center Hotels

Blossom Hotel Houston
Blossom Hotel Houston
4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (3,213 reviews)
"Excellent location, quick checkin and friendly staff, valet guys were top tier professional and gentlemen."

Reviewed on Apr 2, 2025

Blossom Hotel Houston
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
3.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,248 reviews)
"Very close to Texas Children's hospital, you can just walk when visiting someone, they have a parking garage, you do have to pay 20.00 a night and they charge you 50.00 for accidental fee,"

Reviewed on Apr 2, 2025

Hilton Houston Plaza/Medical Center
Hyatt Place Houston Medical Center
Hyatt Place Houston Medical Center
3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,537 reviews)
"Great property to stay great service"

Reviewed on Apr 5, 2025

Hyatt Place Houston Medical Center
InterContinental Houston by IHG
InterContinental Houston by IHG
4 out of 5
6750 Main St, Houston, TX
Fully refundable
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,001 reviews)
"Great very very clean"

Reviewed on Mar 31, 2025

InterContinental Houston by IHG
Hilton Garden Inn Houston Medical Center, TX
Hilton Garden Inn Houston Medical Center, TX
3 out of 5
6840 Almeda Rd, Houston, TX
Stay at this 3-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
9.2/10 Wonderful! (774 reviews)
"The hotel was great and very nice, clean. I will definitely stay again any time I go down to Houston again."

Reviewed on Apr 1, 2025

Hilton Garden Inn Houston Medical Center, TX
The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum District
4 out of 5
1709 DRYDEN ROAD, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
9/10 Wonderful! (1,000 reviews)
"Clean accommodations and friendly staff!!"

Reviewed on Mar 24, 2025

The Westin Houston Medical Center/Museum District
Hyatt House Houston Medical Center
Hyatt House Houston Medical Center
3 out of 5
7329 FANNIN STREET, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (929 reviews)
"Staff was Great, Breakfast was Good, and we loved our room !"

Reviewed on Apr 1, 2025

Hyatt House Houston Medical Center
Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,204 reviews)
"Nice spacious room."

Reviewed on Apr 4, 2025

Club Quarters Hotel Downtown, Houston
Sonesta Hotel Houston IAH Airport
Sonesta Hotel Houston IAH Airport
4 out of 5
425 North Sam Houston Parkway East, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
7.4/10 Good! (1,012 reviews)
"Pretty good hotel to stay at, it's comfortable quiet and clean."

Reviewed on Apr 5, 2025

Sonesta Hotel Houston IAH Airport
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
5353 Westheimer Rd, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,928 reviews)
"Fantastic Hotel this is where I stay when I go to Houston"

Reviewed on Apr 3, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Whitehall Houston
The Whitehall Houston
4 out of 5
1700 Smith St, Houston, TX
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,327 reviews)
"Just would recommend that the valley people would be nicer staff"

Reviewed on Apr 2, 2025

The Whitehall Houston
Hyatt Place Houston-North
Hyatt Place Houston-North
3.5 out of 5
300 Ronan Park Place, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
6.6/10 (948 reviews)
"I like cleaning our room. Thank you so much whoever cleans our room we really appreciate you! Also thank you to the lady at night shift she's very approachable. I love those people!"

Reviewed on Apr 4, 2025

Hyatt Place Houston-North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Texas Medical Center

Houston is a city that has a lot going on, but you have your sights set on Texas Medical Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Texas Medical Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Texas Medical Center hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Houston so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Texas Medical Center underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Texas Medical Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Texas Medical Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Texas Medical Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $80
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Texas Medical Center hotel you want, book it, and never look back. Because your great escape is ahead of you.