Hotels Near
Texas Medical Center

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Featured Texas Medical Center Hotels

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (3,551 reviews)
Room and hotel was fantastic. Be careful ordering door dash. Someone stole my food before I could get down to grab it. But other then that would stay here again.

Reviewed on Nov 8, 2025

Blossom Hotel Houston, Curio Collection by Hilton
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,117 reviews)
I wish there were more options in the breakfast.

Reviewed on Nov 11, 2025

Hyatt Place Houston Medical Center
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
8.2/10 Very Good! (1,655 reviews)
This property is centrally located and amazing to stay at. We had to visit for Medical Reasons so it is walking distance to Methodist Medical Center and also Texas Children’s Hospital. The staff was amazing and very welcoming. The room was very clean and comfortable.

Reviewed on Nov 7, 2025

Hilton Houston Plaza/Medical Center
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,005 reviews)
Needed a place to stay close to our home for a night due to some repair work being done. This fit the bill wonderfully. Very nice hotel with a comfortable and clean room.

Reviewed on Nov 14, 2025

InterContinental Houston by IHG
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
9/10 Wonderful! (1,007 reviews)
Everything about my stay was great and everything went smoothly. Valet was efficient and careful, check-in was easy and the concierge kindly granted my request for a quiet room away from traffic and noise. Room was clean, so nice, and EVERYTHING WORKED (a rarity these days). Terrace 54 Restaurant ...

Reviewed on Nov 10, 2025

The Westin Houston Medical Center/Museum District
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET Houston TX
Fully refundableReserve now, pay when you stay
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular ...
9/10 Wonderful! (1,155 reviews)
Very clean and quiet room. The hospital shuttle service as great!

Reviewed on Nov 9, 2025

Hyatt House Houston Medical Center
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

3 out of 5
6840 Almeda Rd, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,001 reviews)
Clean

Reviewed on Nov 5, 2025

Hilton Garden Inn Houston Medical Center, TX
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (2,855 reviews)
Staff was amazing, friendly and helpful. Some strange housekeeping practices where trash (wrappers, cotton swabs, etc.) were removed from the bins and placed neatly on the bathroom counter instead of removed. Also, there was

Reviewed on Nov 8, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.4/10 Very Good! (3,886 reviews)
Good handicapped room, with space but needs bars to hold onto in shower, toilet has a bar but shower does not. Like the Nespresso machine in the room.

Reviewed on Nov 8, 2025

Club Quarters Hotel Downtown, Houston
Heritage Place Houston Brookhollow

Heritage Place Houston Brookhollow

3 out of 5
2504 North Loop West Houston TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (526 reviews)
位置很便利,以前应该是万豪旗下,现在自营了

Reviewed on Nov 9, 2025

Heritage Place Houston Brookhollow
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4 out of 5
Houston TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.2/10 Very Good! (1,301 reviews)
Fix the escalator coming for the garage.

Reviewed on Nov 7, 2025

DoubleTree by Hilton Hotel Houston - Greenway Plaza
Holiday Inn Houston Downtown by IHG

Holiday Inn Houston Downtown by IHG

3 out of 5
1616 Main St Houston TX
Fully refundable
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,522 reviews)
The coffee machine was broke

Reviewed on Nov 11, 2025

Holiday Inn Houston Downtown by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Texas Medical Center

Houston is a city that has a lot going on, but you have your sights set on Texas Medical Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Texas Medical Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Texas Medical Center hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Houston so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Texas Medical Center underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Texas Medical Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Texas Medical Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Texas Medical Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $100
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Texas Medical Center hotel you want, book it, and never look back. Because your great escape is ahead of you.