Search for Cheap Deals on
5 Star Hotels in Texas Medical Center

Check Last Minute Texas Medical Center Hotel Deals

Tonight Mar 6 - Mar 7This weekend Mar 7 - Mar 9Next weekend Mar 14 - Mar 16

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!

Featured 5 Star Texas Medical Center Hotels

The Post Oak Hotel at Uptown Houston
5 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min drive from MD Anderson Cancer Center
The price is $632 per night from Apr 6 to Apr 7
$632
includes taxes & fees
Apr 6 - Apr 7
Stay at this 5-star luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the room service ...
The Post Oak Hotel at Uptown Houston
ACP Hotel Houston Westchase, MOD Collection by Sonesta
5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min drive from MD Anderson Cancer Center
The price is $99 per night from Mar 9 to Mar 10
$99
includes taxes & fees
Mar 9 - Mar 10
Stay at this 5-star luxury aparthotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
ACP Hotel Houston Westchase, MOD Collection by Sonesta
Four Seasons Hotel Houston
5 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min drive from MD Anderson Cancer Center
The price is $672 per night from Apr 5 to Apr 6
$672
includes taxes & fees
Apr 5 - Apr 6
Stay at this 5-star luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 restaurants. Popular attractions NRG Stadium and Toyota Center are located ...
Four Seasons Hotel Houston
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
JW Marriott Houston Downtown
5 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from MD Anderson Cancer Center
The price is $266 per night from Apr 4 to Apr 5
$266
includes taxes & fees
Apr 4 - Apr 5
Stay at this 5-star luxury hotel in Houston. Enjoy a full-service spa, 24-hour room service, and a health club. Our guests praise the helpful staff and the clean ...
JW Marriott Houston Downtown
The St. Regis Houston
5 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from MD Anderson Cancer Center
The price is $455 per night from Mar 30 to Mar 31
$455
includes taxes & fees
Mar 30 - Mar 31
Stay at this 5-star luxury hotel in Houston. Enjoy a full-service spa, breakfast (surcharge), and 24-hour room service. Popular attractions Houston Zoo and Westheimer ...
The St. Regis Houston
La Colombe d'Or Hotel
5 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from MD Anderson Cancer Center
The price is $546 per night from Mar 12 to Mar 13
$546
includes taxes & fees
Mar 12 - Mar 13
Stay at this 5-star luxury hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions NRG Stadium and Toyota Center ...
La Colombe d'Or Hotel
7550 Kirby Dr
5 out of 5
  • 13 min walk from MD Anderson Cancer Center
The price is $225 per night from Mar 9 to Mar 10
$225
includes taxes & fees
Mar 9 - Mar 10
Stay at this 5-star luxury apartment in Houston. Enjoy free WiFi, free parking, and private pools. Popular attractions NRG Stadium and Houston Zoo are located ...
7550 Kirby Dr
TUSCAN VILLA
5 out of 5
  • 5 min drive from MD Anderson Cancer Center
Stay at this 5-star luxury villa in Houston. Enjoy free WiFi, free parking, and in-room massages. Popular attractions Houston Zoo and NRG Stadium are located ...
Get rates
TUSCAN VILLA
Don't see what you're looking for?
See all available properties in Texas Medical Center
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.