Search for Cheap Deals on
4 Star Hotels in Texas Medical Center

Check Last Minute Texas Medical Center Hotel Deals

Tonight Mar 6 - Mar 7This weekend Mar 7 - Mar 9Next weekend Mar 14 - Mar 16

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!

Featured 4 Star Texas Medical Center Hotels

Club Quarters Hotel Downtown, Houston
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from MD Anderson Cancer Center
The price is $125 per night from Apr 6 to Apr 7
$125
includes taxes & fees
Apr 6 - Apr 7
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from MD Anderson Cancer Center
The price is $143 per night from Apr 4 to Apr 5
$143
includes taxes & fees
Apr 4 - Apr 5
Stay at this hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Whitehall Houston
4 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min drive from MD Anderson Cancer Center
The price is $167 per night from Mar 16 to Mar 17
$167
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
The Whitehall Houston
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Blossom Hotel Houston
4 out of 5
Fully refundableReserve now, pay when you stay
  • 12 min walk from MD Anderson Cancer Center
The price is $192 per night from Mar 23 to Mar 24
$192
includes taxes & fees
Mar 23 - Mar 24
Stay at this 4-star spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
Blossom Hotel Houston
The Royal Sonesta Houston Galleria
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from MD Anderson Cancer Center
The price is $212 per night from Mar 20 to Mar 21
$212
includes taxes & fees
Mar 20 - Mar 21
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
The Royal Sonesta Houston Galleria
Hotel Zaza Houston Museum District
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 23 min walk from MD Anderson Cancer Center
The price is $309 per night from Mar 9 to Mar 10
$309
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4.5-star luxury aparthotel in Houston. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
Hotel Zaza Houston Museum District
The Westin Galleria Houston
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from MD Anderson Cancer Center
The price is $327 per night from Mar 23 to Mar 24
$327
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this eco-certified hotel in Houston. Enjoy free parking, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
The Westin Galleria Houston
DoubleTree by Hilton Hotel Houston - Greenway Plaza
4 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min drive from MD Anderson Cancer Center
The price is $140 per night from Apr 5 to Apr 6
$140
includes taxes & fees
Apr 5 - Apr 6
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
DoubleTree by Hilton Hotel Houston - Greenway Plaza
C. Baldwin, Curio Collection by Hilton
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from MD Anderson Cancer Center
The price is $205 per night from Apr 4 to Apr 5
$205
includes taxes & fees
Apr 4 - Apr 5
Stay at this 4-star hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and a 24-hour fitness center. Our guests praise the helpful staff and ...
C. Baldwin, Curio Collection by Hilton
Hilton Americas-Houston
4 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from MD Anderson Cancer Center
The price is $234 per night from Apr 4 to Apr 5
$234
includes taxes & fees
Apr 4 - Apr 5
Stay at this 4-star spa hotel in Houston. Enjoy a full-service spa, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Hilton Americas-Houston
Hyatt Regency Houston/Galleria
4 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from MD Anderson Cancer Center
The price is $225 per night from Mar 23 to Mar 24
$225
includes taxes & fees
Mar 23 - Mar 24
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Hyatt Regency Houston/Galleria
Houston Marriott Westchase
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from MD Anderson Cancer Center
The price is $121 per night from Apr 5 to Apr 6
$121
includes taxes & fees
Apr 5 - Apr 6
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Houston Marriott Westchase
Don't see what you're looking for?
See all available properties in Texas Medical Center
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.