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Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
  • 45 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,343 reviews)
"Small rooms but convenient stay"

Reviewed on Jul 12, 2026

Club Quarters Hotel Downtown, Houston
Grand Tuscany Hotel

Grand Tuscany Hotel

4 out of 5
12801 Northwest Fwy Houston TX
  • 58 min drive from Sienna
Book a stay at this family-friendly hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the pool and the helpful ...
7.8/10 Good! (160 reviews)
"Pool was way too small."

Reviewed on Jul 9, 2026

Grand Tuscany Hotel
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
  • 41 min drive from Sienna
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (4,263 reviews)
"The hotel was clean and vey accommodating. Parking can be a little tricky in and out of the hotel but manageable. Male hostess was vey nice and welcoming."

Reviewed on Jul 12, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Marriott Marquis Houston

Marriott Marquis Houston

4 out of 5
1777 Walker Street Houston TX
  • 44 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,171 reviews)
"N/a"

Reviewed on Jul 12, 2026

Marriott Marquis Houston
The Moran CITYCENTRE

The Moran CITYCENTRE

4 out of 5
800 Sorella Court Houston TX
  • 48 min drive from Sienna
Book a stay at this boutique hotel in Houston. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,110 reviews)
"The property is nice. A few things are starting to age and need a little maintenance, but still a very nice place. Only disappointment this time we stayed here was that none of the staff seemed like they wanted to be there. No one was particularly rude, but no one had a smile and every interaction ..."

Reviewed on Jul 11, 2026

The Moran CITYCENTRE
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
  • 35 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy a full-service spa, 2 bars/lounges, and a rooftop terrace. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (3,851 reviews)
"Great hotel! Very luxurious and beautiful— parking is convenient however it is only valet and a hefty price for that."

Reviewed on Jul 12, 2026

Blossom Hotel Houston, Curio Collection by Hilton
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
  • 42 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
8.6/10 Excellent! (2,106 reviews)
"This property had issues. Elevators took forever and made so much banging noise; the water in my room would not get hot until maintenance came; the air condition was not steady—air was colder at 77 than it was at 69. This is my last stay at a Sonesta"

Reviewed on Jul 11, 2026

The Royal Sonesta Houston Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
  • 39 min drive from Sienna
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,017 reviews)
"Everything on the property was very great ... we really like the way valet had our car on time when we needed it... we will come again... Thanks for the stay"

Reviewed on Jul 12, 2026

Hotel Zaza Houston Museum District
Hilton Americas-Houston

Hilton Americas-Houston

4 out of 5
1600 Lamar Street Houston TX
  • 43 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy 2 restaurants, 2 bars/lounges, and a rooftop terrace. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,789 reviews)
"The hotel was near walking distance of many attractions (or at least the ones we wanted to visit)!"

Reviewed on Jul 7, 2026

Hilton Americas-Houston
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham

Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham

3 out of 5
13770 Southwest Fwy Sugar Land TX
  • 22 min drive from Sienna
Book a stay at this business-friendly hotel in Sugar Land. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,273 reviews)
"AC doesn’t work every time I’ve gone there (3-4 times ac is always out)"

Reviewed on Jul 12, 2026

Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
  • 37 min drive from Sienna
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
8.4/10 Very Good! (2,029 reviews)
"Great room. No ice machine on our floor. Friendly staff. Beautiful pool."

Reviewed on Jul 12, 2026

Hilton Houston Plaza/Medical Center
Thompson Houston, by Hyatt

Thompson Houston, by Hyatt

4 out of 5
1717 ALLEN PARKWAY Houston TX
  • 45 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (292 reviews)
"The pool area was the best part, and the bartenders"

Reviewed on Jul 9, 2026

Thompson Houston, by Hyatt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Missouri City

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Missouri City.

Choosing the right hotel in Texas has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Missouri City’s 7,150 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $97. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Missouri City hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Missouri City. No matter your reason for visiting Missouri City, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Missouri City hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Missouri City for as low as $97.

How many hotels are there in Missouri City?

With over 7,150 hotels in Missouri City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $97.

How to find cheap car rentals in Missouri City?

Finding a cheap car rental deal in Missouri City is as easy as scoring cheap hotels in Missouri City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.