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Hotels in Missouri City

Choose from 6328 Missouri City Hotel Deals

The Whitehall Houston
The Whitehall Houston
4 out of 5
1700 Smith St, Houston, TX
  • 44 min drive from Sienna
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,582 reviews)
"The staff was superb. We dined at the restaurant several times and the bartender James was especially friendly and thoughtful."

Reviewed on Jul 11, 2025

The Whitehall Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
5353 Westheimer Rd, Houston, TX
  • 41 min drive from Sienna
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (2,201 reviews)
"Expensive"

Reviewed on Jul 11, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
  • 45 min drive from Sienna
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,490 reviews)
Eh..could of been better
"Toilet backed up after only using once to pee. Maintenance was called. Used again the next morning..toilet water overflowed."

Reviewed on Jul 12, 2025

Club Quarters Hotel Downtown, Houston
Hilton Americas-Houston
Hilton Americas-Houston
4 out of 5
1600 Lamar Street, Houston, TX
  • 43 min drive from Sienna
Stay at this 4-star spa hotel in Houston. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,373 reviews)
"Great"

Reviewed on Jul 6, 2025

Hilton Americas-Houston
Cambria Hotel Houston Downtown Convention Center
Cambria Hotel Houston Downtown Convention Center
3 out of 5
1314 Texas Avenue, Houston, TX
  • 44 min drive from Sienna
Stay at this 3-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,555 reviews)
"Grate service"

Reviewed on Jul 13, 2025

Cambria Hotel Houston Downtown Convention Center
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
3 out of 5
13770 Southwest Fwy, Sugar Land, TX
  • 22 min drive from Sienna
Book a stay at this business-friendly hotel in Sugar Land. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,015 reviews)
Heritage Wyndam
"Check in and out process was easy. Breakfast included needed more options like hard boiled eggs. Room was extremely dusty which made it difficult to sleep on my last night."

Reviewed on Jul 10, 2025

Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
Blossom Hotel Houston
Blossom Hotel Houston
4 out of 5
7118 Bertner Ave, Houston, TX
  • 35 min drive from Sienna
Stay at this 4-star spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (3,398 reviews)
Business trip
"I love the hotel. It's very nice, clean and accessible. Front desk was great. Valet parking attendants were great. Central good location for food shopping and partying"

Reviewed on Jul 11, 2025

Blossom Hotel Houston
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Magnolia Hotel Houston, A Tribute Portfolio Hotel
4 out of 5
1100 Texas St, Houston, TX
  • 45 min drive from Sienna
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,016 reviews)
"Great location. Very clean!"

Reviewed on Jul 10, 2025

Magnolia Hotel Houston, A Tribute Portfolio Hotel
Holiday Inn Houston Downtown by IHG
Holiday Inn Houston Downtown by IHG
3 out of 5
1616 Main St, Houston, TX
  • 44 min drive from Sienna
Stay at this 3-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,360 reviews)
"Nice clean rooms"

Reviewed on Jul 11, 2025

Holiday Inn Houston Downtown by IHG
The Laura Hotel, Houston Downtown, Autograph Collection
The Laura Hotel, Houston Downtown, Autograph Collection
4.5 out of 5
1070 Dallas St, Houston, TX
  • 44 min drive from Sienna
Stay at this 4.5-star luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,002 reviews)
"It was great I will say the rooms are quite small and I felt as though for the price I paid it could’ve been way better! Parking there’s rlly no other option other than valet and that cost a pretty penny!"

Reviewed on Jul 10, 2025

The Laura Hotel, Houston Downtown, Autograph Collection
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
4.5 out of 5
6633 Travis St, Houston, TX
  • 37 min drive from Sienna
Stay at this 4.5-star luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,433 reviews)
"Close to MD Anderson Cancer Center. Friendly front desk staff and restaurant staff."

Reviewed on Jul 11, 2025

Hilton Houston Plaza/Medical Center
Hyatt Regency Houston Downtown
Hyatt Regency Houston Downtown
4 out of 5
1200 Louisiana St, Houston, TX
  • 44 min drive from Sienna
Stay at this 4-star eco-certified hotel in Houston. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,040 reviews)
"The city views are amazing"

Reviewed on Jul 13, 2025

Hyatt Regency Houston Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Missouri City

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Missouri City.

Choosing the right hotel in Texas has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Missouri City’s 6,328 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $97. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Missouri City hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Missouri City. No matter your reason for visiting Missouri City, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Missouri City hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Missouri City for as low as $97.

How many hotels are there in Missouri City?

With over 6,328 hotels in Missouri City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $97.

How to find cheap car rentals in Missouri City?

Finding a cheap car rental deal in Missouri City is as easy as scoring cheap hotels in Missouri City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.