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DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
  • 41 min drive from Sienna
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (3,698 reviews)
Great

Reviewed on Apr 5, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
  • 39 min drive from Sienna
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,001 reviews)
Great b

Reviewed on Apr 4, 2026

Hotel Zaza Houston Museum District
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
  • 42 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,762 reviews)
Clean beautiful room

Reviewed on Apr 5, 2026

The Royal Sonesta Houston Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
  • 45 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,061 reviews)
Staff was dismissive to my fiancée at check in, he didn’t like that but everyone I encountered was friendly. Pet friendly but NO places for a dog to go the bathroom. Lots of homeless people around with drugs and many areas that smelled terrible with dumpsters.

Reviewed on Apr 5, 2026

Club Quarters Hotel Downtown, Houston
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
  • 35 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy a full-service spa, 2 bars/lounges, and a rooftop terrace. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (3,753 reviews)
Stayed in Houston to visit some family. Clean and spacious room. It’s an odd location, however, and appears to just be close to hospitals (my fault as I didn’t really look into this). Not a great spot if you want to do any sightseeing or something touristy so would keep that in mind. Was a bit blindsided ...

Reviewed on Apr 5, 2026

Blossom Hotel Houston, Curio Collection by Hilton
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
  • 44 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.6/10 Excellent! (2,085 reviews)
Clean rooms amazing staff the valet guys are so friendly and very helpful !! The restaurants inside the hotel are very good and prices are reasonable. Def our favorite hotel in Houston for short get aways.

Reviewed on Apr 5, 2026

The Whitehall Houston
Heritage Place Houston Brookhollow

Heritage Place Houston Brookhollow

3 out of 5
2504 North Loop West Houston TX
  • 53 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (867 reviews)
Yes

Reviewed on Apr 5, 2026

Heritage Place Houston Brookhollow
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
  • 37 min drive from Sienna
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
8.4/10 Very Good! (1,876 reviews)
Was given the option to upgrade to a suite and breakfast voucher. Excellent service at the front desk. Good staff at breakfast. Food was exceptional. Loved the Self-park option with room key in and out access. Would HIGHLY recommend this location. Also, decor in the lobby is nice with a small but ...

Reviewed on Apr 5, 2026

Hilton Houston Plaza/Medical Center
Omni Houston Hotel

Omni Houston Hotel

4 out of 5
4 Riverway Houston TX
  • 45 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,011 reviews)
N/a

Reviewed on Apr 4, 2026

Omni Houston Hotel
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4 out of 5
Houston TX
  • 40 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.4/10 Very Good! (1,534 reviews)
Good location

Reviewed on Apr 5, 2026

DoubleTree by Hilton Hotel Houston - Greenway Plaza
Hyatt Regency Houston West

Hyatt Regency Houston West

3.5 out of 5
13210 Katy Fwy Houston TX
  • 49 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (1,378 reviews)
Microwave in room

Reviewed on Apr 4, 2026

Hyatt Regency Houston West
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham

Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham

3 out of 5
13770 Southwest Fwy Sugar Land TX
  • 22 min drive from Sienna
Book a stay at this business-friendly hotel in Sugar Land. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,136 reviews)
Good for the price

Reviewed on Apr 5, 2026

Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Missouri City

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Missouri City.

Choosing the right hotel in Texas has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Missouri City’s 6,514 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $97. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Missouri City hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Missouri City. No matter your reason for visiting Missouri City, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Missouri City hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Missouri City for as low as $97.

How many hotels are there in Missouri City?

With over 6,514 hotels in Missouri City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $97.

How to find cheap car rentals in Missouri City?

Finding a cheap car rental deal in Missouri City is as easy as scoring cheap hotels in Missouri City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.