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Hotels in Missouri City

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DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
  • 41 min drive from Sienna
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (4,039 reviews)
"Nice hotel but there are some room for improvements the carpet was torn by the threshold's, drywall repairs and the ac went out in our room they upgraded us same night with o issues but just a few updates would have this a great place. Mike at the front desk, the bartender can’t remember her name ..."

Reviewed on May 20, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
  • 39 min drive from Sienna
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,000 reviews)
"Hotel is beautiful. Room was huge with balcony. Bathroom was clean and big too. Pool area is very attractive. Restaurant which we love provides good food and cocktails. Was nice stay. Thanks we are always love to stay in Zaza hotel."

Reviewed on May 19, 2026

Hotel Zaza Houston Museum District
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
  • 45 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,182 reviews)
"The location is great. Our floor was being painted but this didn’t interrupt the stay. My only issue is the air conditioner. It’s an old central AC system with 3 options: off, extremely loud, and very loud. It is also aimed directly at the bed. Barely slept. If you can “sleep through anything”, then ..."

Reviewed on May 20, 2026

Club Quarters Hotel Downtown, Houston
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
  • 44 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.6/10 Excellent! (2,197 reviews)
"great area staff was very friendly and nice"

Reviewed on May 19, 2026

The Whitehall Houston
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
  • 35 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy a full-service spa, 2 bars/lounges, and a rooftop terrace. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (3,834 reviews)
"Hotel is aesthetically pleasing and very clean. Free wash, average gym that provides water and cold towels but they charge $50 per night for parking, $100 per night for incidentals and $25 for a microwave as they do not come in the room. Valet provides exceptional service and staff is kind. However, ..."

Reviewed on May 20, 2026

Blossom Hotel Houston, Curio Collection by Hilton
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
  • 42 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,922 reviews)
"Great Staff clean rooms"

Reviewed on May 19, 2026

The Royal Sonesta Houston Galleria
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
  • 37 min drive from Sienna
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
8.4/10 Very Good! (1,921 reviews)
"Close to the museum. It’s sooo quiet there it was a bit spooky but I got a really good night sleep after a long day. It’s a clean, standard hotel in a safe place."

Reviewed on May 20, 2026

Hilton Houston Plaza/Medical Center
Grand Tuscany Hotel

Grand Tuscany Hotel

4 out of 5
12801 Northwest Fwy Houston TX
  • 58 min drive from Sienna
Book a stay at this family-friendly hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the pool and the helpful ...
7.6/10 Good! (50 reviews)
"Room smelt like fee. It was very disturbing. Stains on the sheets, glad I always bring my own. The building itself is nice but it needs a lot of improvement"

Reviewed on May 16, 2026

Grand Tuscany Hotel
Hyatt Regency Houston West

Hyatt Regency Houston West

3.5 out of 5
13210 Katy Fwy Houston TX
  • 49 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (1,483 reviews)
"Check in was easy along with friendly staff. They offer fish food to feed the fish in the lobby."

Reviewed on May 18, 2026

Hyatt Regency Houston West
Marriott Marquis Houston

Marriott Marquis Houston

4 out of 5
1777 Walker Street Houston TX
  • 44 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,099 reviews)
"Great and easy check in and check out! The bell hop are great and very convenient"

Reviewed on May 17, 2026

Marriott Marquis Houston
Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel

4 out of 5
1100 Texas St Houston TX
  • 45 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9.2/10 Wonderful! (1,526 reviews)
"There was breakfast buffet and menu options available. The breakfast had great quality!"

Reviewed on May 19, 2026

Magnolia Hotel Houston, A Tribute Portfolio Hotel
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4 out of 5
Houston TX
  • 40 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.4/10 Very Good! (1,602 reviews)
"Compared to the first hotel, Sonesta Essential Houston Hobby Airport that was closed for renovations way after I was booked and they sent us to the second one that wasn’t suitable. The stay at DoubleTree by Hilton Hotel Houston - Greenway Plaza was very suitable, warm, friendly and clean"

Reviewed on May 20, 2026

DoubleTree by Hilton Hotel Houston - Greenway Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Missouri City

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $104. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Missouri City hotel deals at the last minute.

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Frequently Asked Questions About Missouri City hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Missouri City?

With over 6,951 hotels in Missouri City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $104.

How to find cheap car rentals in Missouri City?

Finding a cheap car rental deal in Missouri City is as easy as scoring cheap hotels in Missouri City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.