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DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
  • 41 min drive from Sienna
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (3,686 reviews)
Was a very nice hotel and great location

Reviewed on Apr 3, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
  • 39 min drive from Sienna
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,001 reviews)
Great property!

Reviewed on Apr 2, 2026

Hotel Zaza Houston Museum District
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
  • 42 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,749 reviews)
Room was not that clean .

Reviewed on Apr 3, 2026

The Royal Sonesta Houston Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
  • 45 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,054 reviews)
Front desk had an insane attitude , when we asked for a safe she said there isn’t one safe in the whole hotel, when we asked if we could upgrade she said no you can get another room exactly the same price and condition as your current room. We asked if she was sure ask there were better rooms and ...

Reviewed on Apr 3, 2026

Club Quarters Hotel Downtown, Houston
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
  • 35 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy a full-service spa, 2 bars/lounges, and a rooftop terrace. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (3,746 reviews)
The room was gorgeous and all staff was very friendly

Reviewed on Apr 3, 2026

Blossom Hotel Houston, Curio Collection by Hilton
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
  • 44 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.6/10 Excellent! (2,077 reviews)
Staff very nice. An extra blanket in closet would be great.

Reviewed on Apr 2, 2026

The Whitehall Houston
Heritage Place Houston Brookhollow

Heritage Place Houston Brookhollow

3 out of 5
2504 North Loop West Houston TX
  • 53 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (862 reviews)
The sink was stained and leaking the shower was leaking but the room was spacious and generally clean

Reviewed on Apr 4, 2026

Heritage Place Houston Brookhollow
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
  • 37 min drive from Sienna
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
Hilton Houston Plaza/Medical Center
Omni Houston Hotel

Omni Houston Hotel

4 out of 5
4 Riverway Houston TX
  • 45 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,007 reviews)
N/a

Reviewed on Apr 4, 2026

Omni Houston Hotel
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4 out of 5
Houston TX
  • 40 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.4/10 Very Good! (1,534 reviews)
We didn’t have breakfast or bar the room was clean and staff very nice

Reviewed on Mar 30, 2026

DoubleTree by Hilton Hotel Houston - Greenway Plaza
Hyatt Regency Houston West

Hyatt Regency Houston West

3.5 out of 5
13210 Katy Fwy Houston TX
  • 49 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (1,374 reviews)
I was very annoyed that common sense didn’t take precedence over technicality. My name was misspelled by expedia but, I presented proof of reservation, showed the transaction from my checking account, photo id and they finally needed to see an email with the mispelled/shortened name to honor my reservation. ...

Reviewed on Apr 4, 2026

Hyatt Regency Houston West
Holiday Inn Houston Downtown by IHG

Holiday Inn Houston Downtown by IHG

3 out of 5
1616 Main St Houston TX
  • 43 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,779 reviews)
Ac worked good clean room great staff

Reviewed on Apr 3, 2026

Holiday Inn Houston Downtown by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Missouri City

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Missouri City.

Choosing the right hotel in Texas has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Missouri City’s 6,514 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $112. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Missouri City hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Missouri City. No matter your reason for visiting Missouri City, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Missouri City hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Missouri City for as low as $112.

How many hotels are there in Missouri City?

With over 6,514 hotels in Missouri City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $112.

How to find cheap car rentals in Missouri City?

Finding a cheap car rental deal in Missouri City is as easy as scoring cheap hotels in Missouri City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.