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DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
  • 41 min drive from Sienna
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (3,897 reviews)
The staff were very friendly and nice!! My suite did not have any hand soap or towels. House Keeping was there in two minutes. I customer service was on point.

Reviewed on Apr 27, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
  • 45 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,111 reviews)
Restaurant food in the libby was very.

Reviewed on Apr 27, 2026

Club Quarters Hotel Downtown, Houston
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
  • 35 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy a full-service spa, 2 bars/lounges, and a rooftop terrace. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (3,819 reviews)
Petreese was the absolute best and made sure my stay was enjoyable and amazing

Reviewed on Apr 27, 2026

Blossom Hotel Houston, Curio Collection by Hilton
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
  • 44 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.6/10 Excellent! (2,161 reviews)
Booked hotel to take shuttle to George Brown convention center for three adults and one child. Unable to ride shuttle due to the five-year-old. Cars were in valet to avoid parking by convention center. We had to take Uber to and from for three days. Very disappointed with restaurant on property food ...

Reviewed on Apr 27, 2026

The Whitehall Houston
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
  • 42 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,859 reviews)
Hotel needs updating. Years ago hotel was e exceptional, hotel has excellent location but should provide discounted breakfast and free or greatly reduced parking. The hotel has lost the power to enforce parking privileges to customers. Touch ups needs around the edges all over the hotel. Furniture ...

Reviewed on Apr 27, 2026

The Royal Sonesta Houston Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
  • 39 min drive from Sienna
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,011 reviews)
Very cool redesign of the old Warwick Hotel. Room was very nice with great bedding. Staff was friendly and helpful. Really enjoyed the stay

Reviewed on Apr 27, 2026

Hotel Zaza Houston Museum District
Hyatt Regency Houston West

Hyatt Regency Houston West

3.5 out of 5
13210 Katy Fwy Houston TX
  • 49 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (1,419 reviews)
Koi Pond at the lobby is a wonderful touch and makes this hotel unique. But there are no microwaves in the room and the refrigerator has a note plastered on the front reading: "Caution this cooler is set 55 degrees and will not keep perishable items from spoiling. Please contact the front desk if ...

Reviewed on Apr 27, 2026

Hyatt Regency Houston West
Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel

4 out of 5
1100 Texas St Houston TX
  • 45 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9.2/10 Wonderful! (1,491 reviews)
Everything was awesome. From the vallet parking guys to front desk ladies. Everyone was so sweet and helpful. Not one problem. Everything was clean and easily accessible. Definitely will stay again

Reviewed on Apr 26, 2026

Magnolia Hotel Houston, A Tribute Portfolio Hotel
Marriott Marquis Houston

Marriott Marquis Houston

4 out of 5
1777 Walker Street Houston TX
  • 44 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,104 reviews)
Room was clean

Reviewed on Apr 27, 2026

Marriott Marquis Houston
Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria

4 out of 5
2626 Sage Road Houston TX
  • 41 min drive from Sienna
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,325 reviews)
We really enjoyed our stay here, I think this will be our go to spot when we just want to get away from the house for the weekend.

Reviewed on Apr 23, 2026

Hyatt Regency Houston/Galleria
Omni Houston Hotel

Omni Houston Hotel

4 out of 5
4 Riverway Houston TX
  • 45 min drive from Sienna
Book a stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,004 reviews)
Amazing stay

Reviewed on Apr 27, 2026

Omni Houston Hotel
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
  • 37 min drive from Sienna
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
8.4/10 Very Good! (1,892 reviews)
Good stay for price and location. The room was fairly clean except shower, which was an easy fix. AC worked well and was turned on for check in. The staff were excellent.

Reviewed on Apr 25, 2026

Hilton Houston Plaza/Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Missouri City

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Missouri City.

Choosing the right hotel in Texas has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Missouri City’s 6,827 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $117. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Missouri City hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Missouri City. No matter your reason for visiting Missouri City, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Missouri City hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Missouri City?

With over 6,827 hotels in Missouri City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $117.

How to find cheap car rentals in Missouri City?

Finding a cheap car rental deal in Missouri City is as easy as scoring cheap hotels in Missouri City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.