Hotels Near
Medical District

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Featured Medical District Hotels

La Quinta Inn by Wyndham Huntsville Research Park

La Quinta Inn by Wyndham Huntsville Research Park

3 out of 5
4870 University Dr NW Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (284 reviews)
Room was updated. Good rate for the room. Air conditioner unit was very loud. Indian restaurant next door was delicious.

Reviewed on Dec 31, 2025

La Quinta Inn by Wyndham Huntsville Research Park
The Westin Huntsville

The Westin Huntsville

4 out of 5
6800 Governors Dr W Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (1,002 reviews)
Staff location and amenities.

Reviewed on Dec 31, 2025

The Westin Huntsville
Embassy Suites by Hilton Huntsville

Embassy Suites by Hilton Huntsville

3.5 out of 5
800 Monroe Street Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Huntsville. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,005 reviews)
Nice place - will stay again

Reviewed on Jan 4, 2026

Embassy Suites by Hilton Huntsville
La Quinta Inn & Suites by Wyndham Huntsville Airport Madison

La Quinta Inn & Suites by Wyndham Huntsville Airport Madison

3 out of 5
105 Westchester Drive Madison AL
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Book a stay at this business-friendly hotel in Madison. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,002 reviews)
Staff was courteous

Reviewed on Jan 1, 2026

La Quinta Inn & Suites by Wyndham Huntsville Airport Madison
Best Western Plus Madison-Huntsville Hotel

Best Western Plus Madison-Huntsville Hotel

3 out of 5
9035 Madison Boulevard Madison AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Madison. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,001 reviews)
3 night stay to visit family. Clean room. Needs updating. Comfy beds. Breakfast was really good. A little cold but good. Juice was watery. Staff was top notch. Quiet safe area. Keurig in room was great. Microwave and fridge worked well. Overall I give it 4/5 stars.

Reviewed on Jan 2, 2026

Best Western Plus Madison-Huntsville Hotel
Hyatt Place Huntsville/ Research Park/ Redstone

Hyatt Place Huntsville/ Research Park/ Redstone

3 out of 5
6860 Governors West NW Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,009 reviews)
Nice place!

Reviewed on Jan 3, 2026

Hyatt Place Huntsville/ Research Park/ Redstone
WaterWalk Extended Stay by Wyndham Huntsville

WaterWalk Extended Stay by Wyndham Huntsville

2.5 out of 5
1550 Perimeter Pkwy Huntsville AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Huntsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.4/10 Exceptional! (522 reviews)
Clean room and great space. Location was great because it was near numerous restaurants and shopping areas.

Reviewed on Dec 30, 2025

WaterWalk Extended Stay by Wyndham Huntsville
Clarion Pointe Huntsville Research Park

Clarion Pointe Huntsville Research Park

2.5 out of 5
4815 University Dr Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,002 reviews)
Comfortable beds. Lots of choices & hot food choices at breakfast. Staff was friendly & courteous

Reviewed on Dec 30, 2025

Clarion Pointe Huntsville Research Park
Tru By Hilton Huntsville Research Park Area

Tru By Hilton Huntsville Research Park Area

2.5 out of 5
7026 Cabela Dr NW Huntsville AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Huntsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions US Space and Rocket Center and Von Braun Center are ...
8.2/10 Very Good! (8 reviews)
The hotel was immaculate. My room was sparkling! The free breakfast was delicious. And last but not least the front desk was helpful ands courteous! Would stay again.

Reviewed on Dec 24, 2025

Tru By Hilton Huntsville Research Park Area
Drury Inn & Suites Huntsville at the Space & Rocket Center

Drury Inn & Suites Huntsville at the Space & Rocket Center

3 out of 5
93 Wynn Drive NW Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,002 reviews)
Nice staff and enjoyable experience.

Reviewed on Jan 3, 2026

Drury Inn & Suites Huntsville at the Space & Rocket Center
Sonesta Simply Suites Huntsville Research Park

Sonesta Simply Suites Huntsville Research Park

2 out of 5
201 Exchange Place Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (831 reviews)
It had every amenity that I could think of.

Reviewed on Dec 31, 2025

Sonesta Simply Suites Huntsville Research Park
Woodspring Suites Huntsville - Research Park

Woodspring Suites Huntsville - Research Park

2.5 out of 5
5579 Holmes Ave Huntsville AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Huntsville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions US Space and Rocket Center and Von Braun Center ...
8/10 Very Good! (239 reviews)
Front desk was very nice & accommodating

Reviewed on Dec 25, 2025

Woodspring Suites Huntsville - Research Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Medical District

Huntsville is a city that has a lot going on, but you have your sights set on Medical District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Medical District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Medical District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Huntsville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Medical District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Medical District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Medical District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Medical District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $75
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Medical District hotel you want, book it, and never look back. Because your great escape is ahead of you.