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Hotels in Odessa

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Tonight Apr 12 - Apr 13Next weekend Apr 18 - Apr 20

Choose from 341 Odessa Hotel Deals

MCM Grande Hotel FunDome Odessa
MCM Grande Hotel FunDome Odessa
3 out of 5
6201 E Business I-20, Odessa, TX
  • 10 min drive from Odessa Regional Medical Center
The price is $114 per night from Apr 13 to Apr 14
$114
includes taxes & fees
Apr 13 - Apr 14
Stay at this 3-star business-friendly hotel in Odessa. Enjoy free breakfast, free parking, and room service. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,054 reviews)
"Love the play area for kids. The food is great!"

Reviewed on Apr 9, 2025

MCM Grande Hotel FunDome Odessa
Baymont by Wyndham Odessa
Baymont by Wyndham Odessa
2.5 out of 5
4101 Parks Legado Rd, Odessa, TX
  • 14 min drive from Odessa Regional Medical Center
The price is $92 per night from May 4 to May 5
$92
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Odessa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,125 reviews)
"Great"

Reviewed on Apr 11, 2025

Baymont by Wyndham Odessa
MCM Elegante Hotel and Conference Center Odessa
MCM Elegante Hotel and Conference Center Odessa
3.5 out of 5
5200 E. University Blvd., Odessa, TX
  • 10 min drive from Odessa Regional Medical Center
The price is $128 per night from Apr 13 to Apr 14
$128
includes taxes & fees
Apr 13 - Apr 14
Stay at this 3.5-star spa hotel in Odessa. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
8.8/10 Excellent! (1,004 reviews)
"Decent hotel."

Reviewed on Apr 5, 2025

MCM Elegante Hotel and Conference Center Odessa
Ramada by Wyndham Odessa Near University of Texas Permian
Ramada by Wyndham Odessa Near University of Texas Permian
2.5 out of 5
3001 E Business Loop 20, Odessa, TX
  • 8 min drive from Odessa Regional Medical Center
The price is $62 per night from May 11 to May 12
$62
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Odessa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.6/10 (1,000 reviews)
"Good price. Fresh renovation"

Reviewed on Apr 9, 2025

Ramada by Wyndham Odessa Near University of Texas Permian
Howard Johnson by Wyndham Odessa TX
Howard Johnson by Wyndham Odessa TX
2 out of 5
2925 E. Business Loop 20, Odessa, TX
  • 7 min drive from Odessa Regional Medical Center
The price is $65 per night from May 11 to May 12
$65
includes taxes & fees
May 11 - May 12
Stay at this motel in Odessa. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Ellen Noel Art Museum and Presidential Museum and Leadership ...
6/10 (1,003 reviews)
"Good"

Reviewed on Apr 8, 2025

Howard Johnson by Wyndham Odessa TX
La Quinta Inn & Suites by Wyndham Odessa North
La Quinta Inn & Suites by Wyndham Odessa North
2.5 out of 5
4122 Faudree Rd, Odessa, TX
  • 16 min drive from Odessa Regional Medical Center
The price is $102 per night from Apr 18 to Apr 19
$102
includes taxes & fees
Apr 18 - Apr 19
Book a stay at this business-friendly hotel in Odessa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (438 reviews)
"Is was a nice and comfortable stay"

Reviewed on Apr 11, 2025

La Quinta Inn & Suites by Wyndham Odessa North
Odessa Marriott Hotel & Conference Center
Odessa Marriott Hotel & Conference Center
4 out of 5
305 East 5th Street, Odessa, TX
  • 3 min walk from Odessa Regional Medical Center
The price is $194 per night from Apr 25 to Apr 26
$194
includes taxes & fees
Apr 25 - Apr 26
Stay at this 4-star business-friendly hotel in Odessa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (390 reviews)
"Good clean friendly"

Reviewed on Mar 16, 2025

Odessa Marriott Hotel & Conference Center
Super 8 by Wyndham Odessa TX
Super 8 by Wyndham Odessa TX
2 out of 5
2833 E I 20, Odessa, TX
  • 7 min drive from Odessa Regional Medical Center
The price is $82 per night from Apr 20 to Apr 21
$82
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Odessa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (647 reviews)
"Get what you paid for"

Reviewed on Apr 5, 2025

Super 8 by Wyndham Odessa TX
Extended Stay America Select Suites - Odessa
Extended Stay America Select Suites - Odessa
2 out of 5
3031 E Highway 80, I-20 at exit #12, Odessa, TX
  • 8 min drive from Odessa Regional Medical Center
The price is $106 per night from Apr 19 to Apr 20
$106
includes taxes & fees
Apr 19 - Apr 20
Stay at this hotel in Odessa. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Ellen Noel Art Museum and Presidential Museum and Leadership ...
7.2/10 Good! (69 reviews)
"Everything was great"

Reviewed on Apr 1, 2025

Extended Stay America Select Suites - Odessa
WoodSpring Suites Odessa
WoodSpring Suites Odessa
2.5 out of 5
7051 Tres Hermanas Blvd, Odessa, TX
  • 14 min drive from Odessa Regional Medical Center
The price is $75 per night from Apr 13 to Apr 14
$75
includes taxes & fees
Apr 13 - Apr 14
Stay at this hotel in Odessa. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Stonehenge Replica and Altitude Trampoline Park are ...
6.8/10 (482 reviews)
"The check in was quick and uneventful, clean room but most importantly it was quiet."

Reviewed on Apr 9, 2025

WoodSpring Suites Odessa
Holiday Inn Express & Suites Odessa I-20 by IHG
Holiday Inn Express & Suites Odessa I-20 by IHG
2.5 out of 5
1800 S HWY 385, Odessa, TX
  • 5 min drive from Odessa Regional Medical Center
The price is $107 per night from May 2 to May 3
$107
includes taxes & fees
May 2 - May 3
Book a stay at this business-friendly hotel in Odessa. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff in ...
8.6/10 Excellent! (395 reviews)
"Close to where we were going. Was quiet and beds are comfortable."

Reviewed on Apr 3, 2025

Holiday Inn Express & Suites Odessa I-20 by IHG
La Quinta Inn by Wyndham Odessa
La Quinta Inn by Wyndham Odessa
2.5 out of 5
5001 E Bus I 20, Odessa, TX
  • 9 min drive from Odessa Regional Medical Center
The price is $75 per night from Apr 20 to Apr 21
$75
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly motel in Odessa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7/10 Good! (1,002 reviews)
"Every thing was hood"

Reviewed on Apr 6, 2025

La Quinta Inn by Wyndham Odessa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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