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5 Star Hotels in South Region

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Featured 5 Star South Region Hotels

Sanma Hotel
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $169 per night from Apr 2 to Apr 3
$169
includes taxes & fees
Apr 2 - Apr 3
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
Sanma Hotel
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $743 per night from Apr 22 to Apr 23
$743
includes taxes & fees
Apr 22 - Apr 23
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ...
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Radisson Hotel Curitiba
5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 hours drive from Beto Carrero World
The price is $116 per night from Apr 13 to Apr 14
$116
includes taxes & fees
Apr 13 - Apr 14
Stay at this 5-star luxury hotel in Curitiba. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
Radisson Hotel Curitiba
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DoubleTree by Hilton - Resort - Foz do Iguaçu
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $136 per night from Apr 1 to Apr 2
$136
includes taxes & fees
Apr 1 - Apr 2
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our ...
DoubleTree by Hilton - Resort - Foz do Iguaçu
QOYA Hotel Curitiba, Curio Collection by Hilton
5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 hours drive from Beto Carrero World
The price is $155 per night from Apr 13 to Apr 14
$155
includes taxes & fees
Apr 13 - Apr 14
Stay at this 5-star luxury hotel in Curitiba. Enjoy free WiFi, a full-service spa, and 24-hour room service. Our guests praise the helpful staff in our reviews. ...
QOYA Hotel Curitiba, Curio Collection by Hilton
Wish Foz do Iguaçu
The price is $166 per night from Mar 27 to Mar 28
$166
includes taxes & fees
Mar 27 - Mar 28
Stay at this 5-star luxury resort in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Wish Foz do Iguaçu
Bourbon Hotel & Suítes Curitiba
5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 hours drive from Beto Carrero World
The price is $91 per night from Apr 5 to Apr 6
$91
includes taxes & fees
Apr 5 - Apr 6
Stay at this 5-star luxury hotel in Curitiba. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff and the property ...
Bourbon Hotel & Suítes Curitiba
Wish Serrano Resort
5 out of 5
Fully refundableReserve now, pay when you stay
  • 7 hours drive from Beto Carrero World
The price is $79 per night from Mar 30 to Mar 31
$79
includes taxes & fees
Mar 30 - Mar 31
Stay at this 5-star luxury hotel in Gramado. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Wish Serrano Resort
Bourbon Thermas Eco Resort Cataratas do Iguaçu
The price is $123 per night from Mar 31 to Apr 1
$123
includes taxes & fees
Mar 31 - Apr 1
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cataratas Avenue and Friendship Bridge ...
Bourbon Thermas Eco Resort Cataratas do Iguaçu
Nomaa Hotel
5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 hours drive from Beto Carrero World
The price is $263 per night from Apr 6 to Apr 7
$263
includes taxes & fees
Apr 6 - Apr 7
Stay at this 5-star luxury hotel in Curitiba. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions 24 Hours Street and Japan Square are ...
Nomaa Hotel
Suryaa Hotel Pinhais, Curio Collection by Hilton
5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 hours drive from Beto Carrero World
The price is $178 per night from Apr 21 to Apr 22
$178
includes taxes & fees
Apr 21 - Apr 22
Stay at this 5-star luxury hotel in Pinhais. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Crystal Palace and Botanical Garden ...
Suryaa Hotel Pinhais, Curio Collection by Hilton
Hotel Boutique Quinta das Videiras
5 out of 5
Fully refundableReserve now, pay when you stay
  • 2 hours drive from Beto Carrero World
The price is $231 per night from Mar 31 to Apr 1
$231
includes taxes & fees
Mar 31 - Apr 1
Stay at this 5-star luxury hotel in Florianópolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Hotel Boutique Quinta das Videiras
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5-Star Hotel in South Region

It’s time. No more meh motels and so-so stays. This vacation it’s all about living it up, and that starts with a great hotel. You want first-class service and award-winning restaurants. Well, let us introduce you to a 5-star hotel in South Region.

So nice you’ll blink twice

What makes a hotel worthy of supreme star-age? For starters, the service has to be top-notch and personalized. These hotels often have 24-hour room service, a welcome gift upon your arrival, and help you with your bags—even if you travel light.

Are they nicer? Heck yeah, they are! Most 5-star hotels have jaw-dropping aesthetics that give an authentic feel of class. And we’re not talking about that faux-gold soap dish your Aunt Tilda puts out for the guests—it’s the real deal.

Stars in your eyes

Are 5-stars hotels worth it? If you like the finer things in life, then yes, they sure are. But we also know you’re the type that likes to get your caviar on a fish stick budget. We’re right there with you, and that is why we make it easy to find the best 5-star hotel in South Region for you. Sort by:

  • Price: Want to live large, but keep that budget balanced? We got you. We have 5-star hotels starting at $79.

  • Amenities: South Region skyline view? Maybe a heated indoor pool? Looking for a Michelin-star restaurant? Search for the hotels that have the amenities you desire.

  • Hotwire Hot Rate: We’ll tell you the name of the hotel after you book, and you might just save a ton.

When you’re looking for the top 5-star hotels in South Region—but don’t want to pay top dollar—let us help you out. You can get that posh palace of your dreams, and have money left to take on South Region your way.