Search for Cheap Deals on
Hotels in Barnesville

Check Last Minute Barnesville Hotel Deals

Tonight Apr 25 - Apr 26Next weekend May 1 - May 3

Choose from 189 Barnesville Hotel Deals

Wingate by Wyndham St. Clairsville/Wheeling

Wingate by Wyndham St. Clairsville/Wheeling

2.5 out of 5
51130 National Road E St. Clairsville OH
  • 40 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in St. Clairsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
9.2/10 Wonderful! (1,001 reviews)
pool and hot tub closed. lights in room were not all working. less than optimal number of towels. floors in bathroom had crud built up around the toilet. air vent in bathroom was filthy. staff was friendly. the rooms are well insulated for sound from hallways and neighbors. stay was convenient to ...

Reviewed on Apr 22, 2026

Wingate by Wyndham St. Clairsville/Wheeling
Baymont by Wyndham Cambridge

Baymont by Wyndham Cambridge

2.5 out of 5
61595 Southgate Parkway Cambridge OH
  • 43 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in Cambridge. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,002 reviews)
It's a very friendly and clean hotel

Reviewed on Apr 20, 2026

Baymont by Wyndham Cambridge
Americas Best Value Inn & Suites St. Clairsville Wheeling

Americas Best Value Inn & Suites St. Clairsville Wheeling

2 out of 5
51260 National Road East St. Clairsville OH
  • 40 min drive from WVU Medicine Barnesville Hospital
Stay at this motel in St. Clairsville. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
8.6/10 Excellent! (1,000 reviews)
Plumbing

Reviewed on Apr 21, 2026

Americas Best Value Inn & Suites St. Clairsville Wheeling
Best Western St. Clairsville Inn & Suites

Best Western St. Clairsville Inn & Suites

2.5 out of 5
51654 National Road E St. Clairsville OH
  • 41 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in St. Clairsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
9/10 Wonderful! (856 reviews)
Room was clean and staff was super helpful and polite

Reviewed on Apr 24, 2026

Best Western St. Clairsville Inn & Suites
Holiday Inn Express & Suites Moundsville by IHG

Holiday Inn Express & Suites Moundsville by IHG

2.5 out of 5
225 TELETECH DRIVE Moundsville WV
  • 49 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in Moundsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (465 reviews)
This was the absolute cleanest and quietest hotel I have ever stayed in. The breakfast was hot and delicious. The staff was extremely friendly and helpful.

Reviewed on Apr 22, 2026

Holiday Inn Express & Suites Moundsville by IHG
Microtel Inn & Suites by Wyndham Cambridge

Microtel Inn & Suites by Wyndham Cambridge

2 out of 5
8779 Georgetown Rd Cambridge OH
  • 43 min drive from WVU Medicine Barnesville Hospital
Stay at this hotel in Cambridge. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.4/10 Very Good! (1,000 reviews)
Staff was very nice parking good

Reviewed on Apr 20, 2026

Microtel Inn & Suites by Wyndham Cambridge
Sleep Inn & Suites Moundsville - Wheeling

Sleep Inn & Suites Moundsville - Wheeling

2.5 out of 5
8 Walmart Dr Moundsville WV
  • 48 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in Moundsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (470 reviews)
I was disappointed in the room which was suppose to have walk-in shower. Ran out of hot water in the evening. Was supposed to be for handicap yet the toilet was low Staff was friendly and helpful. Breakfast was nice variety but don’t know that I will stay there again.

Reviewed on Apr 17, 2026

Sleep Inn & Suites Moundsville - Wheeling
Hampton Inn Cambridge

Hampton Inn Cambridge

2.5 out of 5
8775 Georgetown Road Cambridge OH
  • 44 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in Cambridge. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (687 reviews)
This property is wonderful. The staff is very friendly and extra accommodating. The breakfast is great and very pet friendly. I can not say enough about a wonderful stay and experience. Thank you. 😃😃😃

Reviewed on Apr 24, 2026

Hampton Inn Cambridge
Quality Inn Cambridge

Quality Inn Cambridge

2.5 out of 5
1945 Southgate Pkwy Cambridge OH
  • 43 min drive from WVU Medicine Barnesville Hospital
Stay at this hotel in Cambridge. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions The ...
7.8/10 Good! (666 reviews)
The room was out dated and had stains everywhere and had a weird smell. The floor was nasty. My clean feet turned black after a couple steps in the room. The bathroom is extremely small. The bed wasn’t comfortable.

Reviewed on Apr 11, 2026

Quality Inn Cambridge
Microtel Inn & Suites by Wyndham St Clairsville/Wheeling

Microtel Inn & Suites by Wyndham St Clairsville/Wheeling

2 out of 5
51128 National Rd E St. Clairsville OH
  • 40 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in St. Clairsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (965 reviews)
The property was nice and everyone was very helpful. Everything was super clean and the breakfast was yummy. I even worked out in the gym that they had and it did the job.

Reviewed on Apr 21, 2026

Microtel Inn & Suites by Wyndham St Clairsville/Wheeling
Comfort Inn St. Clairsville

Comfort Inn St. Clairsville

2.5 out of 5
52509 National Rd E St. Clairsville OH
  • 42 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in St. Clairsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Comfort Inn St. Clairsville
Red Roof Inn St Clairsville - Wheeling West

Red Roof Inn St Clairsville - Wheeling West

2 out of 5
68301 Red Roof Lane St. Clairsville OH
  • 40 min drive from WVU Medicine Barnesville Hospital
Stay at this hotel in St. Clairsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8.6/10 Excellent! (1,001 reviews)
It's always a nice clean place to stay close to everything. The only thing i didn't like was our smoke free room smelled like cigarettes.

Reviewed on Apr 23, 2026

Red Roof Inn St Clairsville - Wheeling West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Barnesville

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Barnesville hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Barnesville.

Choosing the right hotel in Ohio has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Barnesville’s 189 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $62. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Barnesville hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Barnesville. No matter your reason for visiting Barnesville, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Barnesville hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Barnesville for as low as $62.

How many hotels are there in Barnesville?

With over 189 hotels in Barnesville, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $62.

How to find cheap car rentals in Barnesville?

Finding a cheap car rental deal in Barnesville is as easy as scoring cheap hotels in Barnesville. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.