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Choose from 198 Barnesville Hotel Deals

Wingate by Wyndham St. Clairsville/Wheeling

Wingate by Wyndham St. Clairsville/Wheeling

3 out of 5
51130 National Road E St. Clairsville OH
  • 40 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in St. Clairsville. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (1,003 reviews)
"Wether your stay is a couple days to a week this property is the place to stay."

Reviewed on Nov 7, 2026

Wingate by Wyndham St. Clairsville/Wheeling
SureStay by Best Western Cambridge

SureStay by Best Western Cambridge

3 out of 5
2307 Southgate Parkway Cambridge OH
  • 43 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in Cambridge. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
SureStay by Best Western Cambridge
Microtel Inn & Suites by Wyndham Cambridge

Microtel Inn & Suites by Wyndham Cambridge

2 out of 5
8779 Georgetown Rd Cambridge OH
  • 43 min drive from WVU Medicine Barnesville Hospital
Stay at this hotel in Cambridge. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Microtel Inn & Suites by Wyndham Cambridge
Baymont by Wyndham Cambridge

Baymont by Wyndham Cambridge

2.5 out of 5
61595 Southgate Parkway Cambridge OH
  • 43 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in Cambridge. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Baymont by Wyndham Cambridge
Americas Best Value Inn & Suites St. Clairsville Wheeling

Americas Best Value Inn & Suites St. Clairsville Wheeling

2 out of 5
51260 National Road East St. Clairsville OH
  • 40 min drive from WVU Medicine Barnesville Hospital
Stay at this motel in St. Clairsville. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
Americas Best Value Inn & Suites St. Clairsville Wheeling
Fairfield Inn & Suites Cambridge

Fairfield Inn & Suites Cambridge

3 out of 5
8700 Dozer Rd Cambridge OH
  • 44 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in Cambridge. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (931 reviews)
"Fantastic staff and pool"

Reviewed on Nov 6, 2026

Fairfield Inn & Suites Cambridge
Days Inn & Suites by Wyndham Caldwell

Days Inn & Suites by Wyndham Caldwell

2 out of 5
43945 Marietta Rd Caldwell OH
  • 53 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in Caldwell. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Days Inn & Suites by Wyndham Caldwell
Quality Inn Cambridge

Quality Inn Cambridge

2.5 out of 5
1945 Southgate Pkwy Cambridge OH
  • 43 min drive from WVU Medicine Barnesville Hospital
Stay at this hotel in Cambridge. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions The ...
Quality Inn Cambridge
Holiday Inn Express & Suites Moundsville by IHG

Holiday Inn Express & Suites Moundsville by IHG

2.5 out of 5
225 TELETECH DRIVE Moundsville WV
  • 49 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in Moundsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Moundsville by IHG
Red Roof Inn St Clairsville - Wheeling West

Red Roof Inn St Clairsville - Wheeling West

2 out of 5
68301 Red Roof Lane St. Clairsville OH
  • 40 min drive from WVU Medicine Barnesville Hospital
Stay at this hotel in St. Clairsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8.6/10 Excellent! (1,000 reviews)
"Everything I needed for a travel stop at a great price. Easy highway access. Lots of restaurants around."

Reviewed on Nov 2, 2026

Red Roof Inn St Clairsville - Wheeling West
Days Inn by Wyndham Cambridge

Days Inn by Wyndham Cambridge

3 out of 5
2328 Southgate Pkwy Cambridge OH
  • 43 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in Cambridge. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (384 reviews)
"Parking was good. Breakfast was okay. Staff was great."

Reviewed on Nov 7, 2026

Days Inn by Wyndham Cambridge
Microtel Inn & Suites by Wyndham St Clairsville/Wheeling

Microtel Inn & Suites by Wyndham St Clairsville/Wheeling

3 out of 5
51128 National Rd E St. Clairsville OH
  • 40 min drive from WVU Medicine Barnesville Hospital
Book a stay at this business-friendly hotel in St. Clairsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,009 reviews)
"The staff was exceptionally friendly and helpful. Breakfast was available but not that great although coffee was amazing."

Reviewed on Nov 7, 2026

Microtel Inn & Suites by Wyndham St Clairsville/Wheeling
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Barnesville

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Choosing the right hotel in Ohio has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Barnesville’s 198 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $52. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Barnesville hotel deals at the last minute.

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Frequently Asked Questions About Barnesville hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Barnesville?

With over 198 hotels in Barnesville, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $52.

How to find cheap car rentals in Barnesville?

Finding a cheap car rental deal in Barnesville is as easy as scoring cheap hotels in Barnesville. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.