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Central West End Vacation Packages

Central West End Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Baymont Inn and Suites by Wyndham Farmington, MO
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Tiny Houses of French Village
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Microtel Inn & Suites by Wyndham Sainte Genevieve
Comfort Inn Festus - St Louis South
Red Bud Country Inn
Hampton Inn Farmington

3-4 Night Vacations in Central West End

Price found within the past 48 hours. Click for updated prices.
Hilton Pennywell St. Louis at the Arch
The Wildwood Hotel
 The Royal Sonesta Chase Park Plaza St. Louis
Moonrise Hotel

5-7 Night Vacations in Central West End

Price found within the past 48 hours. Click for updated prices.
Microtel Inn & Suites by Wyndham Sainte Genevieve
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Tiny Houses of French Village
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Cheap Hotel Deals in Central West End

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4 out of 5
4550 Forest Park Ave, St. Louis, MO
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
DoubleTree by Hilton St. Louis Forest Park
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway, St. Louis, MO
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
The Royal Sonesta Chase Park Plaza St. Louis
Aloft St. Louis Cortex

Aloft St. Louis Cortex

3 out of 5
4245 Duncan Avenue, St. Louis, MO
Stay at this 3-star hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms ...
Aloft St. Louis Cortex
Save an average of 15% on thousands of hotels when you're signed in
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

4 out of 5
215 YORK AVENUE, St. Louis, MO
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and ...
AC Hotel St. Louis Central West End
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
Hollywood Casino & Hotel St. Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Clayton Plaza Hotel & Extended Stay
The Last Hotel

The Last Hotel

4.5 out of 5
1501 Washington Ave, St. Louis, MO
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
The Last Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines

Find cheap hotels in Central West End

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Central West End hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central West End.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central West End’s 1,888 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $93. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Central West End hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central West End. No matter your reason for visiting Central West End, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central West End hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central West End for as low as $93.

How many hotels are there in Central West End?

With over 1,888 hotels in Central West End, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $93.

How to find cheap car rentals in Central West End?

Finding a cheap car rental deal in St. Louis is as easy as scoring cheap hotels in Central West End. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Central West End now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Central West End right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.