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Florence Flights as Low as $430

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Cheap Flights to Florence

Fall in love at first flight with your vacation to Florence by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Florence on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Florence, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Florence

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Florence with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DLL airport.

What is the cheapest month to fly to Florence?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Florence are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Florence?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 10 to choose from for your flight to Florence.

What airport is best to fly into Florence?

When you’re planning your trip to Florence, convenience is the name of the game. Luckily, Florence Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Florence must-do list.

How much are flights to Florence?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Florence on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $430, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Florence?

The trick to saving a stack of cash on your flight to Florence? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $430 right now, why wait?

Florence Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$268

Last Minute Hotel Deals in Florence

Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 out of 5
1729 Mandeville Road, Florence, SC
The price is $118 per night from Mar 30 to Mar 31
$118
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,976 reviews)
"It was all good! Stafff"

Reviewed on Mar 23, 2025

Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
The price is $73 per night from Mar 26 to Mar 27
$73
includes taxes & fees
Mar 26 - Mar 27
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,146 reviews)
"Great hotel for the price. Only complaint I have is the shower head. There was either a wide low pressure option or jet stream, nothing in between."

Reviewed on Mar 23, 2025

Howard Johnson by Wyndham Florence
Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center
2.5 out of 5
150 Dunbarton Dr, Florence, SC
The price is $101 per night from Apr 1 to Apr 2
$101
includes taxes & fees
Apr 1 - Apr 2
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,156 reviews)
"It was safe, clean, and quiet,"

Reviewed on Mar 24, 2025

Quality Inn & Suites Florence Civic Center
Comfort Inn & Suites
Comfort Inn & Suites
2.5 out of 5
527 Woody Jones Blvd, Florence, SC
The price is $113 per night from Apr 13 to Apr 14
$113
includes taxes & fees
Apr 13 - Apr 14
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,007 reviews)
Very clean hotel with friendly staff.
"Room was very clean and staff was welcoming."

Reviewed on Mar 23, 2025

Comfort Inn & Suites
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 out of 5
3440 W Radio Dr, Florence, SC
The price is $137 per night from Apr 20 to Apr 21
$137
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,009 reviews)
Decent
"Room was clean. We had a pull out sofa bed but had to go back downstairs to ask for bedding for the sofa bed & extra towels because we had 5 people in the room."

Reviewed on Mar 23, 2025

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
3 out of 5
100 East Evans Street Florence, Florence, SC
The price is $133 per night from Apr 13 to Apr 14
$133
includes taxes & fees
Apr 13 - Apr 14
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,004 reviews)
"Good"

Reviewed on Mar 21, 2025

Hyatt Place Florence Downtown
Days Inn by Wyndham Florence/I-95 North
Days Inn by Wyndham Florence/I-95 North
2 out of 5
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
The price is $70 per night from Apr 24 to Apr 25
$70
includes taxes & fees
Apr 24 - Apr 25
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,004 reviews)
"The floors were dirty. My daughters feet were black after 30 mins of walking on the floor. Everything else was ok."

Reviewed on Mar 20, 2025

Days Inn by Wyndham Florence/I-95 North
Microtel Inn & Suites by Wyndham Florence
Microtel Inn & Suites by Wyndham Florence
2 out of 5
1912 Enterprise Dr, Florence, SC
The price is $59 per night from Mar 30 to Mar 31
$59
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.6/10 (1,002 reviews)
"Nice connecting rooms check in was easy"

Reviewed on Mar 19, 2025

Microtel Inn & Suites by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.