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Florence

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Florence Flights as Low as $336

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Cheap Flights to Florence

Fall in love at first flight with your vacation to Florence by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Florence on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Florence, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Florence

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Florence with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DLL airport.

What is the cheapest month to fly to Florence?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Florence are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Florence?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Florence.

What airport is best to fly into Florence?

When you’re planning your trip to Florence, convenience is the name of the game. Luckily, Florence Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Florence must-do list.

How much are flights to Florence?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Florence on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $336, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Florence?

The trick to saving a stack of cash on your flight to Florence? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $336 right now, why wait?

Florence Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$328

Last Minute Hotel Deals in Florence

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,315 reviews)
"Clean room ,good breakfast"

Reviewed on Jun 26, 2026

Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,682 reviews)
"The property is older and a little outdated. The design looks like military barracks with green grass in the middle. The was furnished alright, however there was hair on 3 of the 4 pillows on the bed, along with red nail polish on obe one of the pillows, and a red dot on the toilet paper that looked ..."

Reviewed on Jun 26, 2026

Howard Johnson by Wyndham Florence
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,304 reviews)
"Clean room, staffs were nice, breakfast was so-so. No cream cheese for bagels. Overall I would stay again"

Reviewed on Jun 26, 2026

Comfort Inn & Suites Florence Center Area
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (210 reviews)
"Staff seemed a bid uncaring Coffee machine didn’t pump properly and I’ve never seen a long line waiting to get coffee before. Staff was notified but didn’t seem to try and correct the problem."

Reviewed on Jun 26, 2026

Quality Inn & Suites Florence Civic Center
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (183 reviews)
"Hotel was clean and well maintained. Staff was helpful, but spent a great deal of time talking to friends and was constantly telling customers "to wait a few minutes". Breakfast was very bad, no eggs in the egg container, "enhanced water' was really water downed juice instead of real juice, meat ..."

Reviewed on Jun 25, 2026

Spark by Hilton Florence North I-95, SC
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,003 reviews)
"I stay here often. I only spent a night this time. I’m glad that the breakfast selection is better! Staff very helpful as always. The condition of the room and property in general, excellent!"

Reviewed on Jun 26, 2026

Hyatt Place Florence Downtown
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
La Quinta Inn & Suites by Wyndham Florence
Comfort Suites Florence I-95

Comfort Suites Florence I-95

2.5 out of 5
2120 West Lucas Street Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,002 reviews)
"Great area and nice hotel!"

Reviewed on Jun 26, 2026

Comfort Suites Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.