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Cheap Flights to Florence

Fall in love at first flight with your vacation to Florence by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Florence on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Florence, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Florence

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Florence with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DLL airport.

What is the cheapest month to fly to Florence?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Florence are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Florence?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Florence.

What airport is best to fly into Florence?

When you’re planning your trip to Florence, convenience is the name of the game. Luckily, Florence Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Florence must-do list.

How much are flights to Florence?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Florence on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Florence?

The trick to saving a stack of cash on your flight to Florence? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Florence Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$456

Last Minute Hotel Deals in Florence

Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 out of 5
1729 Mandeville Road, Florence, SC
The price is $95 per night from Mar 2 to Mar 3
$95
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,936 reviews)
"Nice experience!"

Reviewed on Feb 19, 2025

Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
The price is $68 per night from Feb 24 to Feb 25
$68
includes taxes & fees
Feb 24 - Feb 25
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,088 reviews)
"I stay there frequently, and it is always pleasant, quiet and the staff are very nice and attentive."

Reviewed on Feb 19, 2025

Howard Johnson by Wyndham Florence
Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center
2.5 out of 5
150 Dunbarton Dr, Florence, SC
The price is $98 per night from Mar 9 to Mar 10
$98
includes taxes & fees
Mar 9 - Mar 10
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,104 reviews)
"Met our needs"

Reviewed on Feb 19, 2025

Quality Inn & Suites Florence Civic Center
Comfort Inn & Suites
Comfort Inn & Suites
2.5 out of 5
527 Woody Jones Blvd, Florence, SC
The price is $109 per night from Mar 9 to Mar 10
$109
includes taxes & fees
Mar 9 - Mar 10
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
"I have been doing a lot of traveling lately and this hotel was by far, the most excellent hotel I have stayed in. The breakfast was amazing; the hotel is extremely clean; the staff was friendly and accommodating and caring; the hotel was very pet friendly. Everything about it was wonderful. I can’t ..."

Reviewed on Feb 16, 2025

Comfort Inn & Suites
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel
2.5 out of 5
3440 W Radio Dr, Florence, SC
The price is $111 per night from Mar 9 to Mar 10
$111
includes taxes & fees
Mar 9 - Mar 10
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,003 reviews)
"Totally enjoyed our stay very relaxing, great breakfast,great staff"

Reviewed on Feb 21, 2025

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel
Microtel Inn & Suites by Wyndham Florence
Microtel Inn & Suites by Wyndham Florence
2 out of 5
1912 Enterprise Dr, Florence, SC
The price is $53 per night from Mar 2 to Mar 3
$53
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.6/10 (1,001 reviews)
"Elevator out of order....wake up call ditto breakfast was decent"

Reviewed on Feb 11, 2025

Microtel Inn & Suites by Wyndham Florence
Days Inn by Wyndham Florence/I-95 North
Days Inn by Wyndham Florence/I-95 North
2 out of 5
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
The price is $68 per night from Mar 23 to Mar 24
$68
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,000 reviews)
"Smelled like someone 's cigarette smoke lingering in room only negative for me."

Reviewed on Feb 12, 2025

Days Inn by Wyndham Florence/I-95 North
Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
3 out of 5
100 East Evans Street Florence, Florence, SC
The price is $124 per night from Mar 2 to Mar 3
$124
includes taxes & fees
Mar 2 - Mar 3
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
Only one flaw
"Everything about it was very good. Except the parking. It's a minor inconvenience - and I get the limited options downtown - but it was the only negative to our stay. A hike like that could be a challenge to the elderly, infirmed, or even to everybody in extreme weather. Precipitation, sub-freezing ..."

Reviewed on Feb 19, 2025

Hyatt Place Florence Downtown
See all 303 properties in Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.