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Florence

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Florence Flights as Low as $289

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Cheap Flights to Florence

Fall in love at first flight with your vacation to Florence by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Florence on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Florence, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Florence

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Florence with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DLL airport.

What is the cheapest month to fly to Florence?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Florence are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Florence?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Florence.

What airport is best to fly into Florence?

When you’re planning your trip to Florence, convenience is the name of the game. Luckily, Florence Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Florence must-do list.

How much are flights to Florence?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Florence on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $289, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Florence?

The trick to saving a stack of cash on your flight to Florence? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $289 right now, why wait?

Florence Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$288

Last Minute Hotel Deals in Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,647 reviews)
Not a bad stop if you’re looking for a cheap overnight during a road trip. Check in was quick. Room clean. Overall the building is a little run- down, but we didn’t care since we were just there to sleep.

Reviewed on Apr 25, 2026

Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,259 reviews)
Very impressed. New, clean, well managed. Loved it.

Reviewed on Apr 25, 2026

Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,263 reviews)
The breakfast barely had any food. No fruits(no banana, apples oranges forget the berries) no milk for cereals ,no milk at the coffee station. My first room -the water wasn’t turning on so had to ask for a different room that was located next to the air conditioning unit for the entire hotel. The ...

Reviewed on Apr 25, 2026

Comfort Inn & Suites Florence Center Area
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (106 reviews)
Overnight - traveling… great place, clean and updated! Very attentive , caring staff. Location is wonderful , in walking distance to restaurants and plenty of shops. I will stay again!

Reviewed on Apr 23, 2026

Quality Inn & Suites Florence Civic Center
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,004 reviews)
The hotel was very clean, the staff was nice and helpful, the free breakfast was nice. The only downside was the distance of the parking lot from the hotel.

Reviewed on Apr 24, 2026

Hyatt Place Florence Downtown
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (81 reviews)
Excellent place to stay ,clean rooms and very respectful staff.

Reviewed on Apr 25, 2026

Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2 out of 5
2111 West Lucas St/I-95 Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,005 reviews)
It was nice

Reviewed on Apr 24, 2026

Days Inn by Wyndham Florence/I-95 North
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3 out of 5
2650 Hospitality Boulevard Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
9/10 Wonderful! (809 reviews)
The overall appearance of the property is ok. However you can tell there are several maintenance issues that need to be addressed. Such as painting, replacement of furniture and fixtures. The wear and tear is definitely showing on the furniture, cabinets, tub, caulking and other areas. The auto screen ...

Reviewed on Apr 20, 2026

TownePlace Suites by Marriott Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.