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Park Inn by Radisson Florence, SC
"Rooms was clean quiet , A/C was great very nice stay"
Reviewed on Oct 15, 2026
Howard Johnson by Wyndham Florence
"Staff was helpful, Rooms were definitely an upgrade from the Days Inns I had been staying in!! Continental breakfast was okay, would have liked to have bananas and some yogurt!!"
Reviewed on Oct 15, 2026
Comfort Inn & Suites Florence Center Area
"Room was very clean and modern. Price was good. Good breakfast."
Reviewed on Oct 14, 2026
Spark by Hilton Florence North I-95, SC
Hyatt Place Florence Downtown
Days Inn by Wyndham Florence Near Civic Center
SpringHill Suites by Marriott Florence
Hampton Inn & Suites Florence Center
TownePlace Suites by Marriott Florence
Quality Inn & Suites Florence Civic Center
"This is our third stay at this property. We use this as a one night stopover on our to Florida. The staff are all very courteous, friendly, and professional. You couldn’t ask for a more engaging and helpful hotel staff. My issue with this trip was the location of our room. We were in Room 111. Unfortunately, ..."
Reviewed on Oct 14, 2026
Florence Inn and Suites
La Quinta Inn & Suites by Wyndham Florence
Find cheap hotels in Florence
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Florence.
Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Florence’s 424 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $69. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Florence hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Florence. No matter your reason for visiting Florence, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Florence hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Florence for as low as $69.
How many hotels are there in Florence?
With over 424 hotels in Florence, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $69.
How to find cheap car rentals in Florence?
Finding a cheap car rental deal in Florence is as easy as scoring cheap hotels in Florence. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
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