Search for Cheap Deals on
Hotels in Florence

Check Last Minute Florence Hotel Deals

Tonight May 16 - May 17Next weekend May 22 - May 24

Choose from 392 Florence Hotel Deals

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
  • 9 min drive from Florence Civic Center
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,658 reviews)
Clean comfortable and convenient. The staff was friendly, I could walk to the Starbucks and restaurants. The room was very clean. The bed was very comfortable. Great for this weary traveler.

Reviewed on May 14, 2026

Howard Johnson by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
  • 9 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (142 reviews)
Best night’s sleep I’ve had in forever!! Very pleasant staff! Clean! Will definitely be making this our go to for our trips to Florida and back!!!

Reviewed on May 14, 2026

Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
  • 9 min drive from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,259 reviews)
Carpets are dirty broken picture frame in the room. Breakfast was just ok needs updating

Reviewed on May 15, 2026

Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
  • 7 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,277 reviews)
The property was very nice and in a quiet location while being close to many restaurants and amenities. There is a nice walking trail across from the property. The front desk employee who checked us in was very sweet. The young lady that checked us out was less than friendly and didn't even say thank ...

Reviewed on May 16, 2026

Comfort Inn & Suites Florence Center Area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
  • 9 min drive from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (110 reviews)
We were pleasantly surprised by how comfortable the beds were and how clean everything was considering the price! It’s a great deal for how much we paid!

Reviewed on May 15, 2026

Spark by Hilton Florence North I-95, SC
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
  • 12 min drive from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,004 reviews)
.

Reviewed on May 15, 2026

Hyatt Place Florence Downtown
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

2.5 out of 5
1735 Stokes Road Florence SC
  • 9 min drive from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (909 reviews)
Good basic Hampton Inn. Front desk was very attentive and helpful. The breakfast area and food was the best I’ve had at a Hampton Inn.

Reviewed on May 15, 2026

Hampton Inn & Suites Florence-North-I-95
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

3 out of 5
2670 Hospitality Blvd Florence SC
  • 4 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,006 reviews)
Friendly. Breafast great

Reviewed on May 15, 2026

SpringHill Suites by Marriott Florence
Aloft Florence

Aloft Florence

3 out of 5
820 WOODY JONES BOULEVARD Florence SC
  • 3 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Regal Swamp Fox and Florence ...
8.6/10 Excellent! (328 reviews)
Booked a suite and given a standard room, really messed up our stay as we had multiple kids . Bathroom not clean, no extra toilet paper and only started with half a roll. The modern design of this hotel was silly. No place to hang your towels getting out of the shower, very few amenities in the room ...

Reviewed on May 10, 2026

Aloft Florence
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
  • 8 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,005 reviews)
Front desk was very polite Answered all our questions Quick check in Rooms were very clean Bathroom was very clean

Reviewed on May 15, 2026

Days Inn by Wyndham Florence Near Civic Center
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3 out of 5
2650 Hospitality Boulevard Florence SC
  • 7 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
9/10 Wonderful! (820 reviews)
When I went to take a shower my first day there where towels left behind the door from the last people that stayed in the room. I told the front desk about when I left for the day and asked if they would come and get them and they did not

Reviewed on May 14, 2026

TownePlace Suites by Marriott Florence
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

3 out of 5
150 Westpark Drive Florence SC
  • 9 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (993 reviews)
Clean room

Reviewed on May 15, 2026

Staybridge Suites Florence - Civic Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Florence

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Florence hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Florence.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Florence’s 392 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $74. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Florence hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Florence. No matter your reason for visiting Florence, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Florence hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Florence for as low as $74.

How many hotels are there in Florence?

With over 392 hotels in Florence, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $74.

How to find cheap car rentals in Florence?

Finding a cheap car rental deal in Florence is as easy as scoring cheap hotels in Florence. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.