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Featured Florence Resorts & Hotels with Spas
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr, Florence, SC
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Courtyard by Marriott Florence
2680 Hospitality Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Hampton Inn & Suites Florence Center
3000 W Radio Dr, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hampton Inn & Suites Florence-North-I-95
1735 Stokes Road, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hilton Garden Inn Florence
2671 Hospitality Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in Florence. Enjoy room service, a fitness center, and a garden. Our guests praise the helpful staff in our reviews. ...
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Residence Inn Marriott Florence
2660 Hospitality Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
SpringHill Suites by Marriott Florence
2670 Hospitality Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
The Mantissa Hotel
130 East Carolina Ave, Hartsville, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels by Star Rating
More Hotel Options in Florence
- Hotels with Free Parking in Florence
- Family Hotels in Florence
- Hotels with a Pool in Florence
- Pet-friendly Hotels in Florence
- Beach Hotels in Florence
- Hotels with an Indoor Pool in Florence
- Luxury Hotels in Florence
- Hotels with Hot Tubs in Florence
- Apartment Hotel in Florence
- Hotels with smoking rooms in Florence
Other Accommodation Types
Top Points of Interests in Florence
- Hotels near Florence Civic Center
- Hotels near Magnolia Mall
- Hotels near Francis Marion University
- Hotels near Mcleod Regional Medical Center
- Hotels near Florence Museum
- Hotels near Eastern Carolina Agricultural Fairgrounds
- Hotels near Florence National Cemetery
- Hotels near Oakdale Country Club
- Hotels near The Traces Golf Club
- Hotels near Florence Veterans Park
- Hotels near Columns Plantation
Cities near Florence
- Hartsville Hotels (21.27 mi)
- Dillon Hotels (27.21 mi)
- Cheraw Hotels (35.17 mi)
- Southeastern United States Hotels (264.9 mi)
- Lake City Hotels (22.42 mi)
- The Carolinas Hotels (50.37 mi)
- Latta Hotels (21.48 mi)
- Darlington Hotels (9.59 mi)
- Marion Hotels (21.04 mi)
- Hemingway Hotels (35.7 mi)
- Bennettsville Hotels (29.4 mi)
- Mayesville Hotels (29.02 mi)
- Mullins Hotels (29.34 mi)
- Bishopville Hotels (27.46 mi)
- Aynor Hotels (35.18 mi)
- Timmonsville Hotels (10.89 mi)
- Hamer Hotels (31.63 mi)
- Blenheim Hotels (22.62 mi)
- Lynchburg Hotels (19.91 mi)
- The South Hotels (584.78 mi)
Car Rentals Near Florence
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- Car rentals in Dillon
- Car rentals in Cheraw
- Car rentals in Southeastern United States
- Car rentals in Lake City
- Car rentals in The Carolinas
- Car rentals in Latta
- Car rentals in Darlington
- Car rentals in Marion
- Car rentals in Hemingway
- Car rentals in Bennettsville
- Car rentals in Mayesville
- Car rentals in Mullins
- Car rentals in Bishopville
- Car rentals in Aynor
- Car rentals in Timmonsville
Top Spa Resort Destinations
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Top Booked Hotels in Florence
- Howard Johnson by Wyndham Florence
- Quality Inn & Suites Florence Civic Center
- Hyatt Place Florence Downtown
- La Quinta Inn & Suites by Wyndham Florence
- Microtel Inn & Suites by Wyndham Florence
- Sleep Inn Florence North
- Days Inn by Wyndham Florence Near Civic Center
- Days Inn by Wyndham Florence/I-95 North
- Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG