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Featured Florence Resorts & Hotels with Spas
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel
3440 W Radio Dr, Florence, SC
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Courtyard by Marriott Florence
2680 Hospitality Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Hampton Inn & Suites Florence Center
3000 W Radio Dr, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hampton Inn & Suites Florence-North-I-95
1735 Stokes Road, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hilton Garden Inn Florence
2671 Hospitality Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in Florence. Enjoy room service, a fitness center, and a garden. Our guests praise the helpful staff in our reviews. ...
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Residence Inn Marriott Florence
2660 Hospitality Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
SpringHill Suites by Marriott Florence
2670 Hospitality Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
The Mantissa Hotel
130 East Carolina Ave, Hartsville, SC
Stay at this 3-star hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels by Star Rating
More Hotel Options in Florence
- Hotels with Free Parking in Florence
- Family Hotels in Florence
- Hotels with a Pool in Florence
- Pet-friendly Hotels in Florence
- Beach Hotels in Florence
- Hotels with an Indoor Pool in Florence
- Luxury Hotels in Florence
- Hotels with Hot Tubs in Florence
- Apartment Hotel in Florence
- Hotels with smoking rooms in Florence
Other Accommodation Types
Top Points of Interests in Florence
- Hotels near Florence Civic Center
- Hotels near Magnolia Mall
- Hotels near Mcleod Regional Medical Center
- Hotels near Francis Marion University
- Hotels near Eastern Carolina Agricultural Fairgrounds
- Hotels near Florence National Cemetery
- Hotels near Florence Museum
- Hotels near Florence Veterans Park
- Hotels near Columns Plantation
- Hotels near The Traces Golf Club
- Hotels near Oakdale Country Club
- Hotels near Darlington Raceway
- Hotels near Dillon Motor Speedway
- Hotels near Florence Motor Speedway
- Hotels near Coker College
- Hotels near Lions Park
- Hotels near Beaver Creek Golf Club
- Hotels near Ronald E. McNair Life History Center
Cities near Florence
- Dillon Hotels (27.21 mi)
- Southeastern United States Hotels (264.9 mi)
- Hartsville Hotels (21.27 mi)
- The Carolinas Hotels (50.37 mi)
- Bennettsville Hotels (29.4 mi)
- Latta Hotels (21.48 mi)
- Lake City Hotels (22.42 mi)
- Darlington Hotels (9.59 mi)
- Cheraw Hotels (35.17 mi)
- Marion Hotels (21.04 mi)
- The South Hotels (584.78 mi)
- Timmonsville Hotels (10.89 mi)
- Hemingway Hotels (35.7 mi)
- Mullins Hotels (29.34 mi)
- Hamer Hotels (31.63 mi)
- Bishopville Hotels (27.46 mi)
- Aynor Hotels (35.18 mi)
- Lynchburg Hotels (19.91 mi)
- Turbeville Hotels (25.46 mi)
- Mayesville Hotels (29.02 mi)
Car Rentals Near Florence
- Car rentals in Dillon
- Car rentals in Southeastern United States
- Car rentals in Hartsville
- Car rentals in The Carolinas
- Car rentals in Bennettsville
- Car rentals in Latta
- Car rentals in Lake City
- Car rentals in Darlington
- Car rentals in Cheraw
- Car rentals in Marion
- Car rentals in The South
- Car rentals in Timmonsville
- Car rentals in Hemingway
- Car rentals in Mullins
- Car rentals in Hamer
- Car rentals in Bishopville
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in Florence
- Hyatt Place Florence Downtown
- Howard Johnson by Wyndham Florence
- Quality Inn & Suites Florence Civic Center
- La Quinta Inn & Suites by Wyndham Florence
- Microtel Inn & Suites by Wyndham Florence
- Days Inn by Wyndham Florence/I-95 North
- Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel
- Days Inn by Wyndham Florence Near Civic Center
- Super 8 by Wyndham Florence
- Tru by Hilton Florence I-95