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Hotels in Pamplico

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Choose from 145 Pamplico Hotel Deals

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
  • 7 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,228 reviews)
Great spot friendly staff clean rooms five stars

Reviewed on Feb 15, 2026

Comfort Inn & Suites Florence Center Area
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
  • 9 min drive from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,244 reviews)
Absolutely fabulous staff. The room was clean and well stocked.

Reviewed on Feb 16, 2026

Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
  • 9 min drive from Florence Civic Center
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,571 reviews)
The room was very clean but the bathroom toilet seemed to be missing a bolt on one side that made it loose and wobbly. Other than that great. Th front desk staff was extremely nice and helpful.

Reviewed on Feb 15, 2026

Howard Johnson by Wyndham Florence
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
  • 11 min drive from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,005 reviews)
Excellent location

Reviewed on Feb 16, 2026

Hyatt Place Florence Downtown
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St Florence SC
  • 10 min drive from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,678 reviews)
Room was spotless, Staff upon checking in was great. Hotel seemed a bit old we probably needs remodeling at some point. We were there for a quick night on our way to Florida. It was perfect for what we needed.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Florence
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3 out of 5
2650 Hospitality Boulevard Florence SC
  • 7 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.8/10 Excellent! (760 reviews)
Standard hotel with standard amenities in a standard location by the highway. Pretty much exactly as I expected. No complaints

Reviewed on Feb 14, 2026

TownePlace Suites by Marriott Florence
Residence Inn Marriott Florence

Residence Inn Marriott Florence

3 out of 5
2660 Hospitality Blvd Florence SC
  • 4 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (513 reviews)
The room was large and clean. New. The breakfast was great. I've stayed at Residence Inns a few times and have always had excellent experiences.

Reviewed on Feb 5, 2026

Residence Inn Marriott Florence
Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

2 out of 5
1912 Enterprise Dr Florence SC
  • 10 min drive from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.8/10 (1,000 reviews)
Yes

Reviewed on Feb 14, 2026

Microtel Inn & Suites by Wyndham Florence
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

2.5 out of 5
2101 Florence Harllee Blvd Florence SC
  • 25 min drive from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,009 reviews)
Clean room

Reviewed on Feb 16, 2026

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

2.5 out of 5
3000 W Radio Dr Florence SC
  • 8 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (855 reviews)
Staff was courteous and accommodating. The room was vleaned to satisfaction. Wasnt aware that i needed to request frsh towels daily but the overall visit was good. The contential breakfadt was okay.

Reviewed on Feb 8, 2026

Hampton Inn & Suites Florence Center
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
  • 9 min walk from Florence Civic Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,266 reviews)
Clean room excellent staff

Reviewed on Feb 15, 2026

Quality Inn & Suites Florence Civic Center
Best Western Inn

Best Western Inn

2.5 out of 5
1808 W Lucas Street Florence SC
  • 10 min drive from Florence Civic Center
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Dr. ...
7.6/10 Good! (1,004 reviews)
It was a pleasure. Everything was great.

Reviewed on Feb 18, 2026

Best Western Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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