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Pamplico

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Pamplico Flights as Low as $410

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Sep 30 - Sun, Oct 4
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$410 Roundtrip, found 11 hours ago
$410
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Sep 30 from Newark Liberty Intl. Airport to Florence Regional, returning Sun, Oct 4, priced at $410 found 11 hours ago
American Airlines
Wed, Jul 29 - Sat, Aug 1
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$443 Roundtrip, found 23 hours ago
$443
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Wed, Jul 29 from Newark Liberty Intl. Airport to Florence Regional, returning Sat, Aug 1, priced at $443 found 23 hours ago
American Airlines
Tue, Jul 14 - Sat, Jul 25
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$472 Roundtrip, found 1 day ago
$472
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jul 14 from John F. Kennedy Intl. to Florence Regional, returning Sat, Jul 25, priced at $472 found 1 day ago
American Airlines
Wed, Sep 30 - Sun, Oct 4
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$490 Roundtrip, found 11 hours ago
$490
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Sep 30 from Newark Liberty Intl. Airport to Florence Regional, returning Sun, Oct 4, priced at $490 found 11 hours ago
American Airlines
Tue, Jul 28 - Sat, Aug 1
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$498 Roundtrip, found 23 hours ago
$498
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Tue, Jul 28 from Newark Liberty Intl. Airport to Florence Regional, returning Sat, Aug 1, priced at $498 found 23 hours ago
American Airlines
Thu, Jul 30 - Sat, Aug 1
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$501 Roundtrip, found 23 hours ago
$501
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Thu, Jul 30 from Newark Liberty Intl. Airport to Florence Regional, returning Sat, Aug 1, priced at $501 found 23 hours ago
American Airlines
Wed, Aug 12 - Tue, Sep 1
BWI
Baltimore Washington Intl. Thurgood Marshall
FLO
Florence Regional
$504 Roundtrip, found 21 hours ago
$504
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Wed, Aug 12 from Baltimore Washington Intl. Thurgood Marshall to Florence Regional, returning Tue, Sep 1, priced at $504 found 21 hours ago
American Airlines
Wed, Sep 30 - Sun, Oct 4
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$524 Roundtrip, found 11 hours ago
$524
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Sep 30 from Newark Liberty Intl. Airport to Florence Regional, returning Sun, Oct 4, priced at $524 found 11 hours ago
American Airlines
Mon, Jul 27 - Sat, Aug 1
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$534 Roundtrip, found 23 hours ago
$534
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Mon, Jul 27 from Newark Liberty Intl. Airport to Florence Regional, returning Sat, Aug 1, priced at $534 found 23 hours ago
American Airlines
Tue, Jul 14 - Sat, Jul 25
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$554 Roundtrip, found 1 day ago
$554
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jul 14 from John F. Kennedy Intl. to Florence Regional, returning Sat, Jul 25, priced at $554 found 1 day ago
American Airlines
Tue, Jul 28 - Sun, Aug 2
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$556 Roundtrip, found 23 hours ago
$556
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Tue, Jul 28 from Newark Liberty Intl. Airport to Florence Regional, returning Sun, Aug 2, priced at $556 found 23 hours ago
American Airlines
Thu, Jul 30 - Sun, Aug 2
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$559 Roundtrip, found 23 hours ago
$559
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Thu, Jul 30 from Newark Liberty Intl. Airport to Florence Regional, returning Sun, Aug 2, priced at $559 found 23 hours ago
American Airlines
Wed, Aug 12 - Tue, Sep 1
BWI
Baltimore Washington Intl. Thurgood Marshall
FLO
Florence Regional
$566 Roundtrip, found 21 hours ago
$566
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Wed, Aug 12 from Baltimore Washington Intl. Thurgood Marshall to Florence Regional, returning Tue, Sep 1, priced at $566 found 21 hours ago
American Airlines
Mon, Jul 27 - Sun, Aug 2
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$592 Roundtrip, found 23 hours ago
$592
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Mon, Jul 27 from Newark Liberty Intl. Airport to Florence Regional, returning Sun, Aug 2, priced at $592 found 23 hours ago
American Airlines
Wed, Aug 12 - Tue, Sep 1
BWI
Baltimore Washington Intl. Thurgood Marshall
FLO
Florence Regional
$596 Roundtrip, found 21 hours ago
$596
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Wed, Aug 12 from Baltimore Washington Intl. Thurgood Marshall to Florence Regional, returning Tue, Sep 1, priced at $596 found 21 hours ago
American Airlines
Wed, Sep 30 - Sun, Oct 4
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$616 Roundtrip, found 11 hours ago
$616
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Sep 30 from Newark Liberty Intl. Airport to Florence Regional, returning Sun, Oct 4, priced at $616 found 11 hours ago

Cheap Flights to Pamplico

Fall in love at first flight with your vacation to Pamplico by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Pamplico on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Pamplico, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Pamplico

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Pamplico with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the ADR airport.

What is the cheapest month to fly to Pamplico?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Pamplico are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Pamplico?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Pamplico.

What airport is best to fly into Pamplico?

When you’re planning your trip to Pamplico, convenience is the name of the game. Luckily, Pamplico Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Pamplico must-do list.

How much are flights to Pamplico?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Pamplico on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $410, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Pamplico?

The trick to saving a stack of cash on your flight to Pamplico? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $410 right now, why wait?

Pamplico Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$409

Last Minute Hotel Deals in Pamplico

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,322 reviews)
"Nice place to stay well worth it"

Reviewed on Jun 28, 2026

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Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,671 reviews)
"The breakfast was nothing to write home about. There was black spots on our bed that when we went to wipe it off it smeared. The TV did work. We were only there for like 9 hours but I had reserved a room again for in a week and I canceled that reservation to stay somewhere else for just $45 more ..."

Reviewed on Jun 30, 2026

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Howard Johnson by Wyndham Florence
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,310 reviews)
"Great place to stay. Quiet. Great location. Janice at the front desk was so sweet and very helpful. She is an asset to the staff there for sure."

Reviewed on Jun 30, 2026

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Comfort Inn & Suites Florence Center Area
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (217 reviews)
"Upon arrival I found that the room was attractive, clean, and smelled fresh, no chemical smells or sticky surfaces. I love the colors and simple modern furnishings, comfy bed and fresh, clean bed clothes. I enjoyed being in the room! There was a nice size mini-fridge (with freezer area for ice packs), ..."

Reviewed on Jun 29, 2026

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Quality Inn & Suites Florence Civic Center
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,007 reviews)
"The overall appearance was okay; however, the carpet needs to be replaced or cleaned. The air circulation in the was poor which gave the room a musty smell and the lighting was very dim. The breakfast area was well maintained, the food and the staff (in the breakfast area) were great!"

Reviewed on Jun 29, 2026

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Hyatt Place Florence Downtown
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (188 reviews)
"The toilet of our first room was nasty. I showed splashes of doo doo under the seat and in the bowl. The lady on the front desk was awesome. She changed is to another room. Then we found that the sheets between the comforter and the fitted was missing. Not to mention that the body wash bottle was ..."

Reviewed on Jun 29, 2026

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Spark by Hilton Florence North I-95, SC
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,569 reviews)
"Very rude night staff. Stains and hair on bed sheets, the floors were greasy, furniture was beat up, chair in room had paint stain. The pictures of the room showed two queen size beds and a sofa bed. Front staff said the pictures are wrong and it’s a room with two queen size beds only. I booked it ..."

Reviewed on Jun 30, 2026

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La Quinta Inn & Suites by Wyndham Florence
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2 out of 5
2111 West Lucas St/I-95 Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,004 reviews)
"Half size pillows. Literally half the size of a regular size pillow. 2 towels in a room reserved for 4. TV sound was so bad we couldn't watch. No water in vending. Breakfast closed up at 9am on a Saturday."

Reviewed on Jun 27, 2026

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Days Inn by Wyndham Florence/I-95 North
See all 167 properties in Pamplico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.