Search Cheap Flights to
Pamplico

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Pamplico Flights as Low as $436

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Tue, May 27 - Tue, Jun 3
ORD
O'Hare Intl.
FLO
Florence Regional
$436 Roundtrip, found 4 days ago
$436
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, May 27 from O'Hare Intl. to Florence Regional, returning Tue, Jun 3, priced at $436 found 4 days ago
American Airlines
Mon, May 26 - Tue, Jun 3
ORD
O'Hare Intl.
FLO
Florence Regional
$478 Roundtrip, found 11 hours ago
$478
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Mon, May 26 from O'Hare Intl. to Florence Regional, returning Tue, Jun 3, priced at $478 found 11 hours ago
American Airlines
Sun, May 25 - Fri, Jun 6
ORD
O'Hare Intl.
FLO
Florence Regional
$482 Roundtrip, found 4 days ago
$482
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sun, May 25 from O'Hare Intl. to Florence Regional, returning Fri, Jun 6, priced at $482 found 4 days ago
American Airlines
Fri, May 30 - Fri, Jun 6
ORD
O'Hare Intl.
FLO
Florence Regional
$482 Roundtrip, found 4 days ago
$482
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, May 30 from O'Hare Intl. to Florence Regional, returning Fri, Jun 6, priced at $482 found 4 days ago
American Airlines
Wed, May 28 - Fri, Jun 6
ORD
O'Hare Intl.
FLO
Florence Regional
$488 Roundtrip, found 4 days ago
$488
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, May 28 from O'Hare Intl. to Florence Regional, returning Fri, Jun 6, priced at $488 found 4 days ago
American Airlines
Sun, May 25 - Thu, Jun 5
ORD
O'Hare Intl.
FLO
Florence Regional
$493 Roundtrip, found 4 days ago
$493
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sun, May 25 from O'Hare Intl. to Florence Regional, returning Thu, Jun 5, priced at $493 found 4 days ago
American Airlines
Fri, May 30 - Thu, Jun 5
ORD
O'Hare Intl.
FLO
Florence Regional
$493 Roundtrip, found 4 days ago
$493
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, May 30 from O'Hare Intl. to Florence Regional, returning Thu, Jun 5, priced at $493 found 4 days ago
American Airlines
Tue, May 27 - Fri, Jun 6
ORD
O'Hare Intl.
FLO
Florence Regional
$495 Roundtrip, found 4 days ago
$495
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, May 27 from O'Hare Intl. to Florence Regional, returning Fri, Jun 6, priced at $495 found 4 days ago
American Airlines
Wed, May 28 - Thu, Jun 5
ORD
O'Hare Intl.
FLO
Florence Regional
$499 Roundtrip, found 4 days ago
$499
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, May 28 from O'Hare Intl. to Florence Regional, returning Thu, Jun 5, priced at $499 found 4 days ago
American Airlines
Tue, May 27 - Thu, Jun 5
ORD
O'Hare Intl.
FLO
Florence Regional
$507 Roundtrip, found 4 days ago
$507
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, May 27 from O'Hare Intl. to Florence Regional, returning Thu, Jun 5, priced at $507 found 4 days ago
American Airlines
Mon, May 26 - Fri, Jun 6
ORD
O'Hare Intl.
FLO
Florence Regional
$539 Roundtrip, found 4 days ago
$539
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, May 26 from O'Hare Intl. to Florence Regional, returning Fri, Jun 6, priced at $539 found 4 days ago
American Airlines
Mon, May 26 - Tue, Jun 3
ORD
O'Hare Intl.
FLO
Florence Regional
$549 Roundtrip, found 11 hours ago
$549
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Mon, May 26 from O'Hare Intl. to Florence Regional, returning Tue, Jun 3, priced at $549 found 11 hours ago
American Airlines
Mon, May 26 - Thu, Jun 5
ORD
O'Hare Intl.
FLO
Florence Regional
$550 Roundtrip, found 4 days ago
$550
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, May 26 from O'Hare Intl. to Florence Regional, returning Thu, Jun 5, priced at $550 found 4 days ago
American Airlines
Fri, May 23 - Tue, May 27
SFO
San Francisco Intl.
FLO
Florence Regional
$568 Roundtrip, found 19 hours ago
$568
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Fri, May 23 from San Francisco Intl. to Florence Regional, returning Tue, May 27, priced at $568 found 19 hours ago
American Airlines
Sat, May 24 - Sun, May 25
SFO
San Francisco Intl.
FLO
Florence Regional
$572 Roundtrip, found 19 hours ago
$572
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, May 24 from San Francisco Intl. to Florence Regional, returning Sun, May 25, priced at $572 found 19 hours ago
American Airlines
Sat, May 24 - Tue, May 27
SFO
San Francisco Intl.
FLO
Florence Regional
$599 Roundtrip, found 19 hours ago
$599
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, May 24 from San Francisco Intl. to Florence Regional, returning Tue, May 27, priced at $599 found 19 hours ago

Cheap Flights to Pamplico

Fall in love at first flight with your vacation to Pamplico by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Pamplico on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Pamplico, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Pamplico

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Pamplico with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the ADR airport.

What is the cheapest month to fly to Pamplico?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Pamplico are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Pamplico?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Pamplico.

What airport is best to fly into Pamplico?

When you’re planning your trip to Pamplico, convenience is the name of the game. Luckily, Pamplico Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Pamplico must-do list.

How much are flights to Pamplico?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Pamplico on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $436, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Pamplico?

The trick to saving a stack of cash on your flight to Pamplico? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $436 right now, why wait?

Pamplico Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$435

Last Minute Hotel Deals in Pamplico

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,191 reviews)
"Served it's purpose of a much needed stop off highway to sleep."

Reviewed on May 19, 2025

Get rates
Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 out of 5
1729 Mandeville Road, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,081 reviews)
"Came in after midnight. It’s clean, safe and staff is friendly"

Reviewed on May 19, 2025

Get rates
Park Inn by Radisson Florence, SC
Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center
2.5 out of 5
150 Dunbarton Dr, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,204 reviews)
"Very nice and great help"

Reviewed on May 16, 2025

Get rates
Quality Inn & Suites Florence Civic Center
Comfort Inn & Suites
Comfort Inn & Suites
2.5 out of 5
527 Woody Jones Blvd, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,020 reviews)
"The hotel was convenient for traveling on I95, clean and comfortable. The problem we had was with payment. I booked prior to arrival through Expedia, using both Expedia credit on our account and paying the balance with my credit card. When we checked in we showed the Expedia receipt and booking, ..."

Reviewed on May 20, 2025

Get rates
Comfort Inn & Suites
Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
3 out of 5
100 East Evans Street Florence, Florence, SC
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,007 reviews)
"Hotel was beautiful. Staff was amazing. Enjoyed our stay."

Reviewed on May 19, 2025

Get rates
Hyatt Place Florence Downtown
La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence
2.5 out of 5
2123 W Lucas St, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,653 reviews)
"Well worth the money!"

Reviewed on May 16, 2025

Get rates
La Quinta Inn & Suites by Wyndham Florence
Microtel Inn & Suites by Wyndham Florence
Microtel Inn & Suites by Wyndham Florence
2 out of 5
1912 Enterprise Dr, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.6/10 (1,007 reviews)
Overall good value
"Loud trains in the middle of the night"

Reviewed on May 11, 2025

Get rates
Microtel Inn & Suites by Wyndham Florence
Sleep Inn Florence North
Sleep Inn Florence North
2.5 out of 5
1833 Florence Park Dr, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (616 reviews)
"Great for a overnight"

Reviewed on May 14, 2025

Get rates
Sleep Inn Florence North
See all 133 properties in Pamplico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.