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Choose from 96 Lake City Hotel Deals

The Inn at the Crossroads

The Inn at the Crossroads

2 out of 5
128 West Main Street Lake City SC
  • 9 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (908 reviews)
"Super bel hôtel ! Une belle découverte."

Reviewed on Jun 27, 2026

The Inn at the Crossroads
Quality Inn & Suites Lake City

Quality Inn & Suites Lake City

2.5 out of 5
202 N Ron Mcnair Blvd Lake City SC
  • 8 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (187 reviews)
"No comments"

Reviewed on Jun 26, 2026

Quality Inn & Suites Lake City
Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City

2 out of 5
170 S Ron Mcnair Blvd Lake City SC
  • 8 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Lynches Lake Historical Society ...
6.4/10 (259 reviews)
"The room was great. Very clean. The staff needs lessons in etiquette."

Reviewed on May 17, 2026

Days Inn by Wyndham Lake City
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
  • 54 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (214 reviews)
"This is my 3rd year in a row stay at this establishment and the staff and everything is wonderful I’m looking forward to staying there in 2027 thank Quality Inn Florence ."

Reviewed on Jun 27, 2026

Quality Inn & Suites Florence Civic Center
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
  • 53 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,305 reviews)
"Clean room, staffs were nice, breakfast was so-so. No cream cheese for bagels. Overall I would stay again"

Reviewed on Jun 26, 2026

Comfort Inn & Suites Florence Center Area
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
  • 54 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,002 reviews)
"Clean and great staff. Would definitely return"

Reviewed on Jun 25, 2026

Days Inn by Wyndham Florence Near Civic Center
Courtyard by Marriott Florence

Courtyard by Marriott Florence

3 out of 5
2680 Hospitality Blvd Florence SC
  • 53 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and ...
7.8/10 Good! (752 reviews)
"We went onto the balcony to enjoy the view, and we were locked out for about 20 minutes. The lock fell off the door, and my child was left inside. My daughter is 16 but it could have easily been a minor or toddler left in the room or worse locked outside on the balcony. We were unable to use the ..."

Reviewed on Jun 22, 2026

Courtyard by Marriott Florence
Aloft by Marriott Florence

Aloft by Marriott Florence

3 out of 5
820 WOODY JONES BOULEVARD Florence SC
  • 52 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Popular attractions Regal Swamp ...
8.6/10 Excellent! (356 reviews)
"The property was clean and the room was clean and comfortable."

Reviewed on Jun 28, 2026

Aloft by Marriott Florence
Florence Inn and Suites

Florence Inn and Suites

2.5 out of 5
3821 Bancroft Rd Florence SC
  • 48 min drive from Moore Farms Botanical Garden
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Regal Swamp Fox and Florence Veterans Park are located ...
6.6/10 (378 reviews)
"Nice rooms decent staffs."

Reviewed on Jun 26, 2026

Florence Inn and Suites
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

2.5 out of 5
3000 W Radio Dr Florence SC
  • 54 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (909 reviews)
"Just another McDonalds type hotel. Breakfast was very poor, bacon was a joke, charged 81. 00 for a Frenchie to stay. Was okay not worth $ 300.00"

Reviewed on Jun 24, 2026

Hampton Inn & Suites Florence Center
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

3 out of 5
150 Westpark Drive Florence SC
  • 53 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,002 reviews)
"The room was spacious and cozy. It is close to lots of restaurants and a Target which is a great convenience."

Reviewed on Jun 22, 2026

Staybridge Suites Florence - Civic Center by IHG
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 out of 5
3440 W Radio Dr Florence SC
  • 53 min drive from Moore Farms Botanical Garden
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,002 reviews)
"Our room was extremely clean and comfortable. Will stay here again."

Reviewed on Jun 25, 2026

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Lake City

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How many hotels are there in Lake City?

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