Search for Cheap Deals onHotels in Lake City
Choose from 95 Lake City Hotel Deals
The Inn at the Crossroads
Quality Inn & Suites Lake City
Days Inn by Wyndham Lake City
"Clean, updated furniture and decorations. Friendly staff."
Reviewed on Oct 26, 2026
Comfort Inn & Suites Florence Center Area
Hampton Inn & Suites Florence Center
SpringHill Suites by Marriott Florence
"The hotel pool amd rooms were nice, and there was a big variety for breakfast. Our toilet didn't work well, and the tub slanted inward to the middle but otherwise enjoyable."
Reviewed on Nov 3, 2026
Days Inn by Wyndham Florence Near Civic Center
"The room smelled awful. Water stains, ind bashroom. Roaches under the air conditioner crawning under the baseboard trim. The shower drain ,backed up. The beding did not smell fresh. It was not a restful stay. Room 112"
Reviewed on Nov 6, 2026
TownePlace Suites by Marriott Florence
"My stay was awesome! The entire staff was friendly and extremely helpful on all the small things that can make travel stressful. From the moment I walked in they provided gold star service. Jenine, Kamesha (sp?), Hanna, and the rest of the staff were spectacular. I opening the spellings correct, ..."
Reviewed on Oct 31, 2026
Quality Inn & Suites Florence Civic Center
Aloft by Marriott Florence
Staybridge Suites Florence - Civic Center by IHG
Florence Inn and Suites
Find cheap hotels in Lake City
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Lake City.
Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Lake City’s 95 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Lake City hotel deals at the last minute.
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Frequently Asked Questions About Lake City hotels
Where can I find the best last-minute travel deals?
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How many hotels are there in Lake City?
With over 95 hotels in Lake City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $59.
How to find cheap car rentals in Lake City?
Finding a cheap car rental deal in Lake City is as easy as scoring cheap hotels in Lake City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
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