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Hotels in Hartsville

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Choose from 160 Hartsville Hotel Deals

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

2.5 out of 5
200 S 4th St, Hartsville, SC
  • 5 min drive from Neptune Island Waterpark
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Fairfield Inn by Marriott Hartsville
Quality Inn

Quality Inn

2.5 out of 5
903 S 5th Street, Hartsville, SC
  • 4 min drive from Neptune Island Waterpark
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Hartsville Museum and Hartsville ...
Quality Inn
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

2.5 out of 5
203 East Carolina Ave., Hartsville, SC
  • 5 min drive from Neptune Island Waterpark
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hampton Inn & Suites Hartsville
The Mantissa Hotel

The Mantissa Hotel

3 out of 5
130 East Carolina Ave, Hartsville, SC
  • 5 min drive from Neptune Island Waterpark
Stay at this 3-star hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
The Mantissa Hotel
The Landmark Inn

The Landmark Inn

2.5 out of 5
1301 South 4th Street, Hartsville, SC
  • 6 min drive from Neptune Island Waterpark
Book a stay at this business-friendly motel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
The Landmark Inn
Oak Manor Inn

Oak Manor Inn

3 out of 5
314 EAST HOME AVE, Hartsville, SC
  • 6 min drive from Neptune Island Waterpark
Stay at this 3-star golf B&B in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions East Home Avenue Historic District and Center ...
Oak Manor Inn
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road, Florence, SC
  • 51 min drive from Neptune Island Waterpark
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
  • 51 min drive from Neptune Island Waterpark
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Howard Johnson by Wyndham Florence
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence, Florence, SC
  • 58 min drive from Neptune Island Waterpark
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
Hyatt Place Florence Downtown
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2 out of 5
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
  • 50 min drive from Neptune Island Waterpark
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Florence/I-95 North
Comfort Inn & Suites

Comfort Inn & Suites

2.5 out of 5
527 Woody Jones Blvd, Florence, SC
  • 49 min drive from Neptune Island Waterpark
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
Comfort Inn & Suites
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St, Florence, SC
  • 50 min drive from Neptune Island Waterpark
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
La Quinta Inn & Suites by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Hartsville

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Hartsville.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Hartsville’s 160 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $69. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Hartsville hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Hartsville. No matter your reason for visiting Hartsville, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Hartsville hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Hartsville for as low as $69.

How many hotels are there in Hartsville?

With over 160 hotels in Hartsville, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $69.

How to find cheap car rentals in Hartsville?

Finding a cheap car rental deal in Hartsville is as easy as scoring cheap hotels in Hartsville. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.