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Hotels in Hartsville

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Choose from 160 Hartsville Hotel Deals

Fairfield Inn by Marriott Hartsville
Fairfield Inn by Marriott Hartsville
2.5 out of 5
200 S 4th St, Hartsville, SC
  • 5 min drive from Neptune Island Waterpark
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (629 reviews)
"Very quiet and clean. My only complaint is the few options available for breakfest compared to other hotels."

Reviewed on May 29, 2025

Fairfield Inn by Marriott Hartsville
The Landmark Inn
The Landmark Inn
2.5 out of 5
1301 South 4th Street, Hartsville, SC
  • 6 min drive from Neptune Island Waterpark
Book a stay at this business-friendly motel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (285 reviews)
One nighter
"Room was clean but needed a better comforter."

Reviewed on Apr 21, 2025

The Landmark Inn
Quality Inn
Quality Inn
2.5 out of 5
903 S 5th Street, Hartsville, SC
  • 4 min drive from Neptune Island Waterpark
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Hartsville Museum and Hartsville ...
6/10 (286 reviews)
"It was fine, we were not there much."

Reviewed on May 5, 2025

Quality Inn
Hampton Inn & Suites Hartsville
Hampton Inn & Suites Hartsville
2.5 out of 5
203 East Carolina Ave., Hartsville, SC
  • 5 min drive from Neptune Island Waterpark
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (443 reviews)
"currently undergoing some renovations but the staff are handling it well"

Reviewed on May 4, 2025

Hampton Inn & Suites Hartsville
The Mantissa Hotel
The Mantissa Hotel
3 out of 5
130 East Carolina Ave, Hartsville, SC
  • 5 min drive from Neptune Island Waterpark
Stay at this 3-star hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (238 reviews)
"Our Stay was excellent. Staff was friendly and very professional. Will be back"

Reviewed on Jun 1, 2025

The Mantissa Hotel
Oak Manor Inn
Oak Manor Inn
3 out of 5
314 EAST HOME AVE, Hartsville, SC
  • 6 min drive from Neptune Island Waterpark
Stay at this 3-star golf B&B in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions East Home Avenue Historic District and Center ...
"The south at it’s very best. Beautiful, comfortable and welcoming. I only wish that we’d had longer to stay. David was very friendly and accommodating. I can’t recommend this beautiful home strongly enough. Stay here……you’ll love it."

Reviewed on Sep 16, 2024

Oak Manor Inn
Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
  • 51 min drive from Neptune Island Waterpark
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,213 reviews)
"Good for the 24 hours we needed it"

Reviewed on May 31, 2025

Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 out of 5
1729 Mandeville Road, Florence, SC
  • 51 min drive from Neptune Island Waterpark
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,058 reviews)
"My goto hotel everytime I come to Florence, SC to stay. Highly recommend to anyone. Baby and pet friendly."

Reviewed on Jun 1, 2025

Park Inn by Radisson Florence, SC
Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center
2.5 out of 5
150 Dunbarton Dr, Florence, SC
  • 48 min drive from Neptune Island Waterpark
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,215 reviews)
"Remodelled. Good parking. Quiet."

Reviewed on May 29, 2025

Quality Inn & Suites Florence Civic Center
Comfort Inn & Suites
Comfort Inn & Suites
2.5 out of 5
527 Woody Jones Blvd, Florence, SC
  • 49 min drive from Neptune Island Waterpark
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,008 reviews)
"Room was nice and clean. But the shower only had a shampoo dispenser, the soap dispenser was broken and there was no soap. The exhaust fan in the shower was broken or very weak, so there was no extraction of air or steam. The breakfast was just ok: coffee was warm not hot, eggs tasted ..."

Reviewed on May 31, 2025

Comfort Inn & Suites
Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
3 out of 5
100 East Evans Street Florence, Florence, SC
  • 58 min drive from Neptune Island Waterpark
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,003 reviews)
"Nicely done with the renovation of the property."

Reviewed on May 31, 2025

Hyatt Place Florence Downtown
La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence
3 out of 5
2123 W Lucas St, Florence, SC
  • 50 min drive from Neptune Island Waterpark
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,645 reviews)
"Venus was very helpful and gracious… She greeted us every time we entered or exited the lobby making us feel welcome."

Reviewed on May 30, 2025

La Quinta Inn & Suites by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Hartsville

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $63. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Hartsville hotel deals at the last minute.

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Frequently Asked Questions About Hartsville hotels

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How many hotels are there in Hartsville?

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