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Hartsville

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Hartsville Flights as Low as $461

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Cheap Flights to Hartsville

Fall in love at first flight with your vacation to Hartsville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Hartsville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Hartsville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Hartsville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Hartsville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the FLO airport.

What is the cheapest month to fly to Hartsville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Hartsville are in January, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Hartsville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Hartsville.

What airport is best to fly into Hartsville?

When you’re planning your trip to Hartsville, convenience is the name of the game. Luckily, Hartsville Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Hartsville must-do list.

How much are flights to Hartsville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Hartsville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $461, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Hartsville?

The trick to saving a stack of cash on your flight to Hartsville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $461 right now, why wait?

Hartsville Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$460

Last Minute Hotel Deals in Hartsville

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

3 out of 5
200 S 4th St Hartsville SC
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Fairfield Inn by Marriott Hartsville
The Mantissa Hotel

The Mantissa Hotel

3 out of 5
130 East Carolina Ave Hartsville SC
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (318 reviews)
"We stayed for a wedding. The location is close to restaurants and local shops. Our room was spacious and the staff is friendly. We really enjoyed the rooftop bar!"

Reviewed on Nov 8, 2026

The Mantissa Hotel
The Landmark Inn

The Landmark Inn

2.5 out of 5
1301 South 4th Street Hartsville SC
Book a stay at this business-friendly motel in Hartsville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (350 reviews)
"Very unclean."

Reviewed on Oct 25, 2026

The Landmark Inn
Quality Inn Hartsville

Quality Inn Hartsville

2.5 out of 5
903 S 5th Street Hartsville SC
Stay at this hotel in Hartsville. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Coker Farms National Historic Landmark and Hartsville ...
Quality Inn Hartsville
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

2.5 out of 5
203 East Carolina Ave. Hartsville SC
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (528 reviews)
"K"

Reviewed on Nov 9, 2026

Hampton Inn & Suites Hartsville
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,761 reviews)
"2 night stay. Two separate occasions, hotel staff tried to enter the room without knocking. Without prior notice or complaint by us, 3 hotel staff, a female and 2 males unexpectedly came to the room to check on the tv that working without an issue raised by us. The female staff left the room leaving ..."

Reviewed on Nov 9, 2026

Howard Johnson by Wyndham Florence
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,399 reviews)
"I was not impressed. The room is outdated. Smelt old. Two significant tears in the rug. The mattress was comfortable.👍 I didn’t find anything I’d consider eating for Breakfast. not even the coffee. The staff was friendly"

Reviewed on Nov 10, 2026

Comfort Inn & Suites Florence Center Area
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,504 reviews)
"A clean, comfortable room with a helpful staff and nice breakfast."

Reviewed on Nov 10, 2026

Park Inn by Radisson Florence, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.