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Hartsville

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Hartsville Flights as Low as $298

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Jul 16 - Tue, Jul 22
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$298 Roundtrip, found 3 days ago
$298
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Jul 16 from Newark Liberty Intl. Airport to Florence Regional, returning Tue, Jul 22, priced at $298 found 3 days ago
American Airlines
Tue, Jul 15 - Wed, Jul 23
LGA
LaGuardia
FLO
Florence Regional
$298 Roundtrip, found 12 hours ago
$298
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Tue, Jul 15 from LaGuardia to Florence Regional, returning Wed, Jul 23, priced at $298 found 12 hours ago
American Airlines
Tue, Jul 1 - Thu, Jul 10
ICT
Wichita Dwight D. Eisenhower National
FLO
Florence Regional
$342 Roundtrip, found 4 days ago
$342
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Jul 1 from Wichita Dwight D. Eisenhower National to Florence Regional, returning Thu, Jul 10, priced at $342 found 4 days ago
American Airlines
Wed, Jul 16 - Mon, Jul 21
LGA
LaGuardia
FLO
Florence Regional
$346 Roundtrip, found 13 hours ago
$346
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Jul 16 from LaGuardia to Florence Regional, returning Mon, Jul 21, priced at $346 found 13 hours ago
American Airlines
Mon, Jun 30 - Thu, Jul 10
ICT
Wichita Dwight D. Eisenhower National
FLO
Florence Regional
$350 Roundtrip, found 4 days ago
$350
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Jun 30 from Wichita Dwight D. Eisenhower National to Florence Regional, returning Thu, Jul 10, priced at $350 found 4 days ago
American Airlines
Tue, Jul 1 - Thu, Jul 10
ICT
Wichita Dwight D. Eisenhower National
FLO
Florence Regional
$352 Roundtrip, found 2 days ago
$352
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jul 1 from Wichita Dwight D. Eisenhower National to Florence Regional, returning Thu, Jul 10, priced at $352 found 2 days ago
American Airlines
Mon, Jun 30 - Mon, Jul 7
ICT
Wichita Dwight D. Eisenhower National
FLO
Florence Regional
$359 Roundtrip, found 12 hours ago
$359
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Mon, Jun 30 from Wichita Dwight D. Eisenhower National to Florence Regional, returning Mon, Jul 7, priced at $359 found 12 hours ago
American Airlines
Tue, Jul 15 - Wed, Jul 23
LGA
LaGuardia
FLO
Florence Regional
$361 Roundtrip, found 12 hours ago
$361
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Tue, Jul 15 from LaGuardia to Florence Regional, returning Wed, Jul 23, priced at $361 found 12 hours ago
American Airlines
Tue, Oct 7 - Sat, Oct 11
PHL
Philadelphia Intl.
FLO
Florence Regional
$363 Roundtrip, found 3 days ago
$363
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Oct 7 from Philadelphia Intl. to Florence Regional, returning Sat, Oct 11, priced at $363 found 3 days ago
American Airlines
Tue, Jul 15 - Wed, Jul 23
LGA
LaGuardia
FLO
Florence Regional
$370 Roundtrip, found 12 hours ago
$370
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Tue, Jul 15 from LaGuardia to Florence Regional, returning Wed, Jul 23, priced at $370 found 12 hours ago
American Airlines
Tue, Jul 1 - Thu, Jul 10
ICT
Wichita Dwight D. Eisenhower National
FLO
Florence Regional
$372 Roundtrip, found 2 days ago
$372
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jul 1 from Wichita Dwight D. Eisenhower National to Florence Regional, returning Thu, Jul 10, priced at $372 found 2 days ago
American Airlines
Mon, Jun 30 - Mon, Jul 7
ICT
Wichita Dwight D. Eisenhower National
FLO
Florence Regional
$379 Roundtrip, found 12 hours ago
$379
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Mon, Jun 30 from Wichita Dwight D. Eisenhower National to Florence Regional, returning Mon, Jul 7, priced at $379 found 12 hours ago
American Airlines
Mon, Jun 30 - Thu, Jul 10
ICT
Wichita Dwight D. Eisenhower National
FLO
Florence Regional
$381 Roundtrip, found 3 days ago
$381
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jun 30 from Wichita Dwight D. Eisenhower National to Florence Regional, returning Thu, Jul 10, priced at $381 found 3 days ago
American Airlines
Tue, Jul 15 - Tue, Jul 22
DFW
Dallas-Fort Worth Intl.
FLO
Florence Regional
$419 Roundtrip, found 1 day ago
$419
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jul 15 from Dallas-Fort Worth Intl. to Florence Regional, returning Tue, Jul 22, priced at $419 found 1 day ago
American Airlines
Sun, Jul 13 - Sun, Jul 20
SHV
Shreveport Regional
FLO
Florence Regional
$470 Roundtrip, found 1 day ago
$470
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Jul 13 from Shreveport Regional to Florence Regional, returning Sun, Jul 20, priced at $470 found 1 day ago
American Airlines
Mon, Jun 16 - Sat, Jun 21
TPA
Tampa Intl.
FLO
Florence Regional
$472 Roundtrip, found 13 hours ago
$472
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Mon, Jun 16 from Tampa Intl. to Florence Regional, returning Sat, Jun 21, priced at $472 found 13 hours ago

Cheap Flights to Hartsville

Fall in love at first flight with your vacation to Hartsville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Hartsville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Hartsville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Hartsville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Hartsville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the FLO airport.

What is the cheapest month to fly to Hartsville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Hartsville are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Hartsville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Hartsville.

What airport is best to fly into Hartsville?

When you’re planning your trip to Hartsville, convenience is the name of the game. Luckily, Hartsville Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Hartsville must-do list.

How much are flights to Hartsville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Hartsville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $298, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Hartsville?

The trick to saving a stack of cash on your flight to Hartsville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $298 right now, why wait?

Hartsville Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$298

Last Minute Hotel Deals in Hartsville

Fairfield Inn by Marriott Hartsville
Fairfield Inn by Marriott Hartsville
2.5 out of 5
200 S 4th St, Hartsville, SC
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (629 reviews)
"Very quiet and clean. My only complaint is the few options available for breakfest compared to other hotels."

Reviewed on May 29, 2025

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Fairfield Inn by Marriott Hartsville
Quality Inn
Quality Inn
2.5 out of 5
903 S 5th Street, Hartsville, SC
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Hartsville Museum and Hartsville ...
6/10 (289 reviews)
"Everything was amazing"

Reviewed on Jun 6, 2025

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Quality Inn
The Landmark Inn
The Landmark Inn
2.5 out of 5
1301 South 4th Street, Hartsville, SC
Book a stay at this business-friendly motel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (286 reviews)
One nighter
"Room was clean but needed a better comforter."

Reviewed on Apr 21, 2025

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The Landmark Inn
Hampton Inn & Suites Hartsville
Hampton Inn & Suites Hartsville
2.5 out of 5
203 East Carolina Ave., Hartsville, SC
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (445 reviews)
"currently undergoing some renovations but the staff are handling it well"

Reviewed on May 4, 2025

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Hampton Inn & Suites Hartsville
The Mantissa Hotel
The Mantissa Hotel
3 out of 5
130 East Carolina Ave, Hartsville, SC
Stay at this 3-star hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (238 reviews)
"Our Stay was excellent. Staff was friendly and very professional. Will be back"

Reviewed on Jun 1, 2025

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The Mantissa Hotel
Oak Manor Inn
Oak Manor Inn
3 out of 5
314 EAST HOME AVE, Hartsville, SC
Stay at this 3-star golf B&B in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions East Home Avenue Historic District and Center ...
"The south at it’s very best. Beautiful, comfortable and welcoming. I only wish that we’d had longer to stay. David was very friendly and accommodating. I can’t recommend this beautiful home strongly enough. Stay here……you’ll love it."

Reviewed on Sep 16, 2024

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Oak Manor Inn
Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,218 reviews)
"All good. Bathroom could use some wall hooks to hang hand and bath towels. Room is good."

Reviewed on Jun 14, 2025

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Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 out of 5
1729 Mandeville Road, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,062 reviews)
"."

Reviewed on Jun 14, 2025

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Park Inn by Radisson Florence, SC
See all 162 properties in Hartsville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.