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Hartsville

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Hartsville Flights as Low as $324

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Cheap Flights to Hartsville

Fall in love at first flight with your vacation to Hartsville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Hartsville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Hartsville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Hartsville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Hartsville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the FLO airport.

What is the cheapest month to fly to Hartsville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Hartsville are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Hartsville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Hartsville.

What airport is best to fly into Hartsville?

When you’re planning your trip to Hartsville, convenience is the name of the game. Luckily, Hartsville Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Hartsville must-do list.

How much are flights to Hartsville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Hartsville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $324, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Hartsville?

The trick to saving a stack of cash on your flight to Hartsville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $324 right now, why wait?

Hartsville Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$323

Last Minute Hotel Deals in Hartsville

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

2.5 out of 5
200 S 4th St Hartsville SC
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (689 reviews)
Amanda at the front desk was super friendly and I enjoyed talking to her and her recommendations! Room was very clean and quiet. Will stay again if in the area!

Reviewed on Jan 14, 2026

Fairfield Inn by Marriott Hartsville
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

2.5 out of 5
203 East Carolina Ave. Hartsville SC
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (487 reviews)
Breakfast options are always great. My daughter has a lot of allergies but she is aways excited to good eat breakfast.

Reviewed on Jan 23, 2026

Hampton Inn & Suites Hartsville
The Landmark Inn

The Landmark Inn

2.5 out of 5
1301 South 4th Street Hartsville SC
Book a stay at this business-friendly motel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (315 reviews)
Had a late check in @11pm. Front desk rep was friendly and professional. Check in was quick. Room was very clean. Bathroom was very clean. Sheets and pillows were clean and bed was very comfortable. No hassle about late checkout. Cleaning staff were very respectful and courteous. Excellent stay. ...

Reviewed on Dec 7, 2025

The Landmark Inn
The Mantissa Hotel

The Mantissa Hotel

3 out of 5
130 East Carolina Ave Hartsville SC
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (272 reviews)
This was an outstanding hotel We will stay again when in town

Reviewed on Jan 18, 2026

The Mantissa Hotel
Quality Inn

Quality Inn

2.5 out of 5
903 S 5th Street Hartsville SC
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Hartsville Museum and Hartsville ...
6/10 (332 reviews)
The place is good for visiting and relaxing when coming to town.

Reviewed on Jan 2, 2026

Quality Inn
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,250 reviews)
Clean room. Hard to adjust temperature in the room. Conveniently located

Reviewed on Jan 23, 2026

Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,191 reviews)
Most comfortable bed I’ve ever slept in .

Reviewed on Jan 21, 2026

Comfort Inn & Suites Florence Center Area
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,550 reviews)
Clean room, friendly staff, nice parking facility and most importantly the price is very reasonable for a small family to stay there! HIGHLY RECOMMENDED!!

Reviewed on Jan 23, 2026

Howard Johnson by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.