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Featured Florence Family Hotels
Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Dr. Eddie Floyd Tennis Center ...
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr, Florence, SC
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Fairfield Inn by Marriott Hartsville
200 S 4th St, Hartsville, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Dillon
823 Radford Blvd, Dillon, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
The Landmark Inn
1301 South 4th Street, Hartsville, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Comfort Suites Florence I-95
2120 West Lucas Street, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Florence
Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Dr. Eddie Floyd Tennis Center ...
"Still in Renovation mode"
Reviewed on Sep 3, 2024
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2101 Florence Harllee Blvd, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,003 reviews)
"We stayed at the same place last year and booked again at the same hotel. We absolutely loved our 1st stay and had to come back. Friendly staff and clean rooms."
Reviewed on Jul 1, 2025
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,001 reviews)
"The staff were friendly. Breakfast was satisfying. Great for a family."
Reviewed on Jul 5, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Florence
Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Dr. Eddie Floyd Tennis Center ...
Comfort Suites Florence I-95
2120 West Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with Free Parking in Florence
- Hotels with a Pool in Florence
- Pet-friendly Hotels in Florence
- Beach Hotels in Florence
- Hotels with an Indoor Pool in Florence
- Luxury Hotels in Florence
- Hotels with Hot Tubs in Florence
- Resorts & Hotels with Spas in Florence
- Apartment Hotel in Florence
- Hotels with smoking rooms in Florence
Other Accommodation Types
Top Points of Interests in Florence
- Hotels near Florence Civic Center
- Hotels near Magnolia Mall
- Hotels near Mcleod Regional Medical Center
- Hotels near Francis Marion University
- Hotels near Eastern Carolina Agricultural Fairgrounds
- Hotels near Florence National Cemetery
- Hotels near Florence Museum
- Hotels near Florence Veterans Park
- Hotels near The Traces Golf Club
- Hotels near Oakdale Country Club
- Hotels near Columns Plantation
Cities near Florence
- Dillon Hotels (27.21 mi)
- Hartsville Hotels (21.27 mi)
- Southeastern United States Hotels (264.9 mi)
- The Carolinas Hotels (50.37 mi)
- Latta Hotels (21.48 mi)
- Cheraw Hotels (35.17 mi)
- Lake City Hotels (22.42 mi)
- Darlington Hotels (9.59 mi)
- Marion Hotels (21.04 mi)
- Hemingway Hotels (35.7 mi)
- Bennettsville Hotels (29.4 mi)
- Mayesville Hotels (29.02 mi)
- Aynor Hotels (35.18 mi)
- Mullins Hotels (29.34 mi)
- Bishopville Hotels (27.46 mi)
- Timmonsville Hotels (10.89 mi)
- Hamer Hotels (31.63 mi)
- Galivants Ferry Hotels (31.37 mi)
- Lynchburg Hotels (19.91 mi)
- Blenheim Hotels (22.62 mi)
Car Rentals Near Florence
- Car rentals in Dillon
- Car rentals in Hartsville
- Car rentals in Southeastern United States
- Car rentals in The Carolinas
- Car rentals in Latta
- Car rentals in Cheraw
- Car rentals in Lake City
- Car rentals in Darlington
- Car rentals in Marion
- Car rentals in Hemingway
- Car rentals in Bennettsville
- Car rentals in Mayesville
- Car rentals in Aynor
- Car rentals in Mullins
- Car rentals in Bishopville
- Car rentals in Timmonsville
Top Family Hotel Destinations
- Las Vegas Family Hotels
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- Colorado Springs Family Hotels
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- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in Florence
- Howard Johnson by Wyndham Florence
- Hyatt Place Florence Downtown
- La Quinta Inn & Suites by Wyndham Florence
- Days Inn by Wyndham Florence/I-95 North
- Quality Inn & Suites Florence Civic Center
- TownePlace Suites by Marriott Florence
- Days Inn by Wyndham Florence Near Civic Center
- Microtel Inn & Suites by Wyndham Florence
- Staybridge Suites Florence - Civic Center by IHG
- SpringHill Suites by Marriott Florence
- Tru by Hilton Florence I-95
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
- Comfort Suites Florence I-95