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Featured Luxury Florence
![The Mantissa Hotel](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/5583982a_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
The Mantissa Hotel
130 East Carolina Ave, Hartsville, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
![Days Inn by Wyndham Dillon](https://images.trvl-media.com/lodging/1000000/110000/105100/105003/4fc62706_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Days Inn by Wyndham Dillon
823 Radford Blvd, Dillon, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
![Hotel Florence, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/bedd4b68_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/3ba2ede7_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
![Baymont Inn & Suites Florence by Wyndham](https://images.trvl-media.com/lodging/1000000/10000/500/460/7cc7addd_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Beaver Creek Golf Club and Palmetto ...
![Clarion Inn & Suites](https://images.trvl-media.com/lodging/1000000/20000/13400/13359/fce1208f_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Clarion Inn & Suites
1819 West Lucas Street, Building A, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Beaver Creek Golf Club and Palmetto Shores Lake are located ...
![Red Roof Inn Florence - Civic Center](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/ada13811_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
![Days Inn by Wyndham Florence Near Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/8ec127ac_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
![Quality Inn & Suites](https://images.trvl-media.com/lodging/1000000/10000/2100/2009/5ae762d4_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Quality Inn & Suites
817 Radford Blvd, Dillon, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/a20ba9f2_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
![Red Roof Inn Dillon, SC](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/2b946657_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Red Roof Inn Dillon, SC
810 Radford Boulevard, Dillon, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
![Super 8 by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/870000/861500/861452/dd4c54c1_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Super 8 by Wyndham Florence
1832 1/2 Lucas Street, I95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels by Star Rating
More Hotel Options in Florence
- Hotels with Free Parking in Florence
- Family Hotels in Florence
- Hotels with a Pool in Florence
- Pet-friendly Hotels in Florence
- Beach Hotels in Florence
- Hotels with an Indoor Pool in Florence
- Hotels with Hot Tubs in Florence
- Resorts & Hotels with Spas in Florence
- Apartment Hotel in Florence
- Hotels with smoking rooms in Florence
Other Accommodation Types
Top Points of Interests in Florence
- Hotels near Florence Civic Center
- Hotels near Magnolia Mall
- Hotels near Mcleod Regional Medical Center
- Hotels near Francis Marion University
- Hotels near Eastern Carolina Agricultural Fairgrounds
- Hotels near Florence Museum
- Hotels near Florence National Cemetery
- Hotels near Florence Veterans Park
- Hotels near The Traces Golf Club
- Hotels near Oakdale Country Club
- Hotels near Columns Plantation
- Hotels near Darlington Raceway
- Hotels near Florence Motor Speedway
- Hotels near Coker College
- Hotels near Dillon Motor Speedway
- Hotels near Neptune Island Waterpark
- Hotels near Lions Park
- Hotels near Beaver Creek Golf Club
- Hotels near The Country Club at Lake City
Cities near Florence
- Southeastern United States Hotels (264.9 mi)
- Hartsville Hotels (21.27 mi)
- The Carolinas Hotels (50.37 mi)
- Dillon Hotels (27.21 mi)
- Darlington Hotels (9.59 mi)
- Cheraw Hotels (35.17 mi)
- Lake City Hotels (22.42 mi)
- Latta Hotels (21.48 mi)
- Marion Hotels (21.04 mi)
- Bennettsville Hotels (29.4 mi)
- Hemingway Hotels (35.7 mi)
- The South Hotels (584.78 mi)
- Mullins Hotels (29.34 mi)
- Timmonsville Hotels (10.89 mi)
- Mayesville Hotels (29.02 mi)
- Bishopville Hotels (27.46 mi)
- Aynor Hotels (35.18 mi)
- Hamer Hotels (31.63 mi)
- Galivants Ferry Hotels (31.37 mi)
- Lynchburg Hotels (19.91 mi)
Car Rentals Near Florence
- Car rentals in Southeastern United States
- Car rentals in Hartsville
- Car rentals in The Carolinas
- Car rentals in Dillon
- Car rentals in Darlington
- Car rentals in Cheraw
- Car rentals in Lake City
- Car rentals in Latta
- Car rentals in Marion
- Car rentals in Bennettsville
- Car rentals in Hemingway
- Car rentals in The South
- Car rentals in Mullins
- Car rentals in Timmonsville
- Car rentals in Mayesville
- Car rentals in Bishopville
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- Shreveport Luxury Hotels
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Top Booked Hotels in Florence
- Quality Inn & Suites Florence Civic Center
- Hyatt Place Florence Downtown
- Howard Johnson by Wyndham Florence
- Microtel Inn & Suites by Wyndham Florence
- Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel
- Days Inn by Wyndham Florence/I-95 North
- Staybridge Suites Florence - Civic Center, an IHG Hotel
- Tru by Hilton Florence I-95
- La Quinta Inn & Suites by Wyndham Florence