Search for Cheap Deals onLuxury & Trendy Hotels in Florence
Check Last Minute Florence Hotel Deals
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Hotels in Florence

Hotel Florence, Tapestry Collection by Hilton
Fully refundableReserve now, pay when you stay
The price is $157 per night from Apr 20 to Apr 21
$157
includes taxes & fees
Apr 20 - Apr 21
Stay at this 3-star spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...

The Inn at the Crossroads
Fully refundableReserve now, pay when you stay
The price is $156 per night from Mar 30 to Mar 31
$156
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

The Mantissa Hotel
Fully refundableReserve now, pay when you stay
The price is $201 per night from Mar 30 to Mar 31
$201
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
- Top Hotels by Star Rating
- More Hotel Types
- Other Accommodation Options
- Popular Attractions
- Nearby Cities
Hotels by Star Rating
More Hotel Options in Florence
- Hotels with Free Parking in Florence
- Family Hotels in Florence
- Hotels with a Pool in Florence
- Pet-friendly Hotels in Florence
- Beach Hotels in Florence
- Hotels with an Indoor Pool in Florence
- Luxury Hotels in Florence
- Hotels with Hot Tubs in Florence
- Resorts & Hotels with Spas in Florence
- Apartment Hotel in Florence
More Accommodation Options in Florence
Top Attractions in Florence
- Hotels near Florence Civic Center
- Hotels near Magnolia Mall
- Hotels near Mcleod Regional Medical Center
- Hotels near Francis Marion University
- Hotels near Eastern Carolina Agricultural Fairgrounds
- Hotels near Florence Museum
- Hotels near Florence National Cemetery
- Hotels near Oakdale Country Club
- Hotels near Florence Veterans Park
- Hotels near The Traces Golf Club
- Hotels near Columns Plantation
- Hotels near Darlington Raceway
- Hotels near Florence Motor Speedway
- Hotels near Coker College
- Hotels near Neptune Island Waterpark
- Hotels near Dillon Motor Speedway
- Hotels near Beaver Creek Golf Club
- Hotels near Lions Park
- Hotels near Moore Farms Botanical Garden
- Hartsville Hotels (21.27 mi)
- Darlington Hotels (9.59 mi)
- Dillon Hotels (27.21 mi)
- The Carolinas Hotels (50.37 mi)
- Southeastern United States Hotels (264.9 mi)
- Cheraw Hotels (35.17 mi)
- Lake City Hotels (22.42 mi)
- Latta Hotels (21.48 mi)
- Marion Hotels (21.04 mi)
- Hemingway Hotels (35.7 mi)
- Bennettsville Hotels (29.4 mi)
- Timmonsville Hotels (10.89 mi)
Top Booked Hotels in Florence
- Howard Johnson by Wyndham Florence
- Quality Inn & Suites Florence Civic Center
- Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
- Hyatt Place Florence Downtown
- Days Inn by Wyndham Florence/I-95 North
- Microtel Inn & Suites by Wyndham Florence
- Days Inn by Wyndham Florence Near Civic Center
- La Quinta Inn & Suites by Wyndham Florence
- Staybridge Suites Florence - Civic Center by IHG
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Top Boutique Hotel Destinations
- Des Moines Boutique Hotel
- Knoxville Boutique Hotel
- Flagstaff Boutique Hotel
- Rochester Boutique Hotel
- Reno Boutique Hotel
- Raleigh Boutique Hotel
- Anchorage Boutique Hotel
- Fort Myers Boutique Hotel
- Grand Rapids Boutique Hotel
- Zion National Park Boutique Hotel
- Palm Beach Boutique Hotel
- Niagara Falls Boutique Hotel
- Spokane Boutique Hotel
- Springfield Boutique Hotel
- Orlando Boutique Hotel
- Mammoth Lakes Boutique Hotel
- Tallahassee Boutique Hotel
- Oakland Boutique Hotel
- Atlantic City Boutique Hotel
- Shenandoah Valley Boutique Hotel
Car Rentals Near Florence
- Car rentals in Hartsville
- Car rentals in Darlington
- Car rentals in Dillon
- Car rentals in The Carolinas
- Car rentals in Southeastern United States
- Car rentals in Cheraw
- Car rentals in Lake City
- Car rentals in Latta
- Car rentals in Marion
- Car rentals in Hemingway
- Car rentals in Bennettsville
- Car rentals in Timmonsville
- Car rentals in Bishopville
- Car rentals in Mayesville
- Car rentals in Mullins
- Car rentals in Aynor