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Murphysboro

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Cheap Flights to Murphysboro

Fall in love at first flight with your vacation to Murphysboro by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Murphysboro on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Murphysboro, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Murphysboro

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Murphysboro with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MDH airport.

What is the cheapest month to fly to Murphysboro?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Murphysboro are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Murphysboro?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Murphysboro.

What airport is best to fly into Murphysboro?

When you’re planning your trip to Murphysboro, convenience is the name of the game. Luckily, Murphysboro Williamson County Regional Airport is nearby so you can deplane and get going on checking off everything on your Murphysboro must-do list.

How much are flights to Murphysboro?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Murphysboro on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Murphysboro?

The trick to saving a stack of cash on your flight to Murphysboro? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Murphysboro Flight Information
Destination airport
Murphysboro
Destination airport IATA code
MDH

Last Minute Hotel Deals in Murphysboro

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
120 MUDDY MONSTER ROAD Murphysboro IL
Book a stay at this business-friendly hotel in Murphysboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (519 reviews)
Yes, very clean and service was great.

Reviewed on Jan 27, 2026

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St Marion IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,014 reviews)
The hotel was one of the cleanest I have been in! We enjoyed the breakfast and the evening meal.

Reviewed on Jan 25, 2026

Drury Inn & Suites Marion
Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 out of 5
777 Walkers Bluff Way Carterville IL
Book a stay at this luxury resort in Carterville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (405 reviews)
The room was clean. Staff was amazing. Bed was comfy.

Reviewed on Jan 30, 2026

Walker's Bluff Casino Resort
Baymont by Wyndham Marion

Baymont by Wyndham Marion

2.5 out of 5
2608 W Main St Marion IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,079 reviews)
Room was clean and shower was excellent.

Reviewed on Jan 28, 2026

Baymont by Wyndham Marion
Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale

2 out of 5
1180 E Main St Carbondale IL
Book a stay at this business-friendly motel in Carbondale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,013 reviews)
Clean room, friendly staff

Reviewed on Jan 25, 2026

Super 8 by Wyndham Carbondale
University Inn of Carbondale

University Inn of Carbondale

2.5 out of 5
2400 W Main St Carbondale IL
Book a stay at this business-friendly hotel in Carbondale. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff ...
6/10 (335 reviews)
The room was alright, it needed cleaned a litter better..... The staff on the kiosk, was nice, however, the woman was not very kind at all

Reviewed on Jan 22, 2026

University Inn of Carbondale
Quality Inn And Suites

Quality Inn And Suites

2.5 out of 5
2600 W Main St Marion IL
Stay at this hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy beds in our reviews. Popular ...
7.2/10 Good! (1,001 reviews)
Everyone was nice

Reviewed on Jan 28, 2026

Quality Inn And Suites
Best Western Marion Hotel

Best Western Marion Hotel

2.5 out of 5
400 Comfort Dr Marion IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,004 reviews)
The front desk staff was very friendly and helpful.

Reviewed on Jan 26, 2026

Best Western Marion Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.