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Myrtle

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Myrtle Flights as Low as $459

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$459 Roundtrip, found 6 hours ago
$459
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $459 found 6 hours ago
American Airlines
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$479 Roundtrip, found 6 hours ago
$479
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $479 found 6 hours ago
American Airlines
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$487 Roundtrip, found 6 hours ago
$487
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $487 found 6 hours ago
American Airlines
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$509 Roundtrip, found 6 hours ago
$509
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $509 found 6 hours ago
American Airlines
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$526 Roundtrip, found 6 hours ago
$526
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $526 found 6 hours ago
American Airlines
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$530 Roundtrip, found 6 hours ago
$530
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $530 found 6 hours ago
American Airlines
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$600 Roundtrip, found 6 hours ago
$600
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $600 found 6 hours ago
United
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$636 Roundtrip, found 6 hours ago
$636
Roundtrip
found 6 hours ago
Select United flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $636 found 6 hours ago
United
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$644 Roundtrip, found 6 hours ago
$644
Roundtrip
found 6 hours ago
Select United flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $644 found 6 hours ago
American Airlines
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$658 Roundtrip, found 6 hours ago
$658
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $658 found 6 hours ago
United
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$678 Roundtrip, found 6 hours ago
$678
Roundtrip
found 6 hours ago
Select United flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $678 found 6 hours ago
United
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$701 Roundtrip, found 6 hours ago
$701
Roundtrip
found 6 hours ago
Select United flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $701 found 6 hours ago
American Airlines
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$724 Roundtrip, found 6 hours ago
$724
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $724 found 6 hours ago
American Airlines
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$743 Roundtrip, found 6 hours ago
$743
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $743 found 6 hours ago
United
Tue, Nov 25 - Wed, Dec 3
CVG
Cincinnati - Northern Kentucky Intl.
TUP
Tupelo Regional
$745 Roundtrip, found 6 hours ago
$745
Roundtrip
found 6 hours ago
Select United flight, departing Tue, Nov 25 from Cincinnati - Northern Kentucky Intl. to Tupelo Regional, returning Wed, Dec 3, priced at $745 found 6 hours ago
American Airlines
Wed, Aug 6 - Tue, Aug 12
JAC
Jackson Hole
TUP
Tupelo Regional
$783 Roundtrip, found 14 hours ago
$783
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Wed, Aug 6 from Jackson Hole to Tupelo Regional, returning Tue, Aug 12, priced at $783 found 14 hours ago

Cheap Flights to Myrtle

Fall in love at first flight with your vacation to Myrtle by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Myrtle on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Myrtle, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Myrtle

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Myrtle with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TUP airport.

What is the cheapest month to fly to Myrtle?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Myrtle are in November, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Myrtle?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Myrtle.

What airport is best to fly into Myrtle?

When you’re planning your trip to Myrtle, convenience is the name of the game. Luckily, Myrtle University - Oxford Airport is nearby so you can deplane and get going on checking off everything on your Myrtle must-do list.

How much are flights to Myrtle?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Myrtle on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $459, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Myrtle?

The trick to saving a stack of cash on your flight to Myrtle? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $459 right now, why wait?

Myrtle Flight Information
Destination airport
Tupelo Regional
Destination airport IATA code
TUP
Roundtrip price
$459

Last Minute Hotel Deals in Myrtle

La Quinta Inn & Suites by Wyndham Oxford

La Quinta Inn & Suites by Wyndham Oxford

3 out of 5
1171 Frontage Road, Oxford, MS
Stay at this 3-star business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (788 reviews)
"Friendly staff and clean property."

Reviewed on Jul 24, 2025

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La Quinta Inn & Suites by Wyndham Oxford
Tru by Hilton Oxford

Tru by Hilton Oxford

2.5 out of 5
97 Ed Perry Blvd, Oxford, MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (771 reviews)
Good stay
"It was a good stay. The room was average and well kept."

Reviewed on Jul 27, 2025

Get rates
Tru by Hilton Oxford
Graduate by Hilton Oxford

Graduate by Hilton Oxford

4 out of 5
400 North Lamar Boulevard, Oxford, MS
Stay at this 4-star business-friendly hotel in Oxford. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the bar and the helpful staff ...
8.8/10 Excellent! (1,000 reviews)
"This hotel was suggested by a waitress in Memphis - we were so glad to stay at the Graduate in Oxford! The hotel was cheerful and decorated well. Room was spacious and clean. This is our new favorite spot, and hope to visit more Graduates in the future."

Reviewed on Jul 25, 2025

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Graduate by Hilton Oxford
The Inn at Ole Miss

The Inn at Ole Miss

3 out of 5
120 Alumni Drive, University, MS
Stay at this 3-star business-friendly hotel in University. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
"The lobby, restaurant and location of this hotel cannot be beat. EXTREMELY convenient, and can only imagine it's amazing during Ole Miss sporting events! Our room was modest - a bit dated but fine for our taste. The room's move-in condition was clean (we don't do daily maid service), however the ..."

Reviewed on Jul 29, 2025

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The Inn at Ole Miss
Best Western New Albany

Best Western New Albany

2.5 out of 5
400 State Highway 30 W, New Albany, MS
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,005 reviews)
"Thr best"

Reviewed on Jul 26, 2025

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Best Western New Albany
Hampton Inn New Albany

Hampton Inn New Albany

2.5 out of 5
320 Coulter Cv, New Albany, MS
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
8.4/10 Very Good! (684 reviews)
"The staff was great!"

Reviewed on Jul 27, 2025

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Hampton Inn New Albany
The Oliver Hotel, Oxford

The Oliver Hotel, Oxford

4 out of 5
425 S Lamar Blvd, Oxford, MS
Stay at this 4-star hotel in Oxford. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (275 reviews)
"One of the best hotels we have stayed in. Excellent!"

Reviewed on Jul 23, 2025

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The Oliver Hotel, Oxford
Holiday Inn Express New Albany by IHG

Holiday Inn Express New Albany by IHG

2.5 out of 5
300 Highway 30, New Albany, MS
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (508 reviews)
Family vacation
"Travel this route yearly for vacation. First time to stop here, but will put at top of our list for future. Easy access and food choices around were good. Hotel clean and all staff great. Good breakfast options."

Reviewed on Jul 20, 2025

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Holiday Inn Express New Albany by IHG
See all 549 properties in Myrtle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.