Search for Cheap Deals on
Hotels in Myrtle

Check Last Minute Myrtle Hotel Deals

Tonight Feb 15 - Feb 16Next weekend Feb 20 - Feb 22

Choose from 605 Myrtle Hotel Deals

La Quinta Inn & Suites by Wyndham Oxford

La Quinta Inn & Suites by Wyndham Oxford

3 out of 5
1171 Frontage Road Oxford MS
  • 25 min walk from University of Mississippi
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (951 reviews)
Awesome place close to downtown

Reviewed on Feb 7, 2026

La Quinta Inn & Suites by Wyndham Oxford
The Inn at Ole Miss

The Inn at Ole Miss

3 out of 5
120 Alumni Drive University MS
  • 7 min walk from University of Mississippi
Book a stay at this business-friendly hotel in University. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
Always the very best!

Reviewed on Jan 20, 2026

The Inn at Ole Miss
Tru by Hilton Oxford

Tru by Hilton Oxford

2.5 out of 5
97 Ed Perry Blvd Oxford MS
  • 6 min drive from University of Mississippi
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (904 reviews)
clean room

Reviewed on Feb 11, 2026

Tru by Hilton Oxford
Graduate by Hilton Oxford

Graduate by Hilton Oxford

4 out of 5
400 North Lamar Boulevard Oxford MS
  • 22 min walk from University of Mississippi
Book a stay at this business-friendly hotel in Oxford. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,000 reviews)
Room was clean. Mattress uncomfortable, hotel features not conducive to having products. Shower very outdated. Staff was very friendly.

Reviewed on Jan 23, 2026

Graduate by Hilton Oxford
 The Oliver Hotel, Oxford

The Oliver Hotel, Oxford

4 out of 5
425 S Lamar Blvd Oxford MS
  • 21 min walk from University of Mississippi
Stay at this hotel in Oxford. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (330 reviews)
Great

Reviewed on Feb 10, 2026

The Oliver Hotel, Oxford
Best Western New Albany

Best Western New Albany

2.5 out of 5
400 State Highway 30 W New Albany MS
  • 1 hour drive from University of Mississippi
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,001 reviews)
Clean, Friendly Staff

Reviewed on Feb 10, 2026

Best Western New Albany
Courtyard by Marriott Oxford

Courtyard by Marriott Oxford

3 out of 5
305 Jackson Avenue East Oxford MS
  • 11 min walk from University of Mississippi
Book a stay at this business-friendly hotel in Oxford. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (537 reviews)
5stars

Reviewed on Jan 31, 2026

Courtyard by Marriott Oxford
Hampton Inn Oxford/Conference Center

Hampton Inn Oxford/Conference Center

2.5 out of 5
103 Ed Perry Blvd Oxford MS
  • 6 min drive from University of Mississippi
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (499 reviews)
Rooms were clean and staff was super friendly.

Reviewed on Jan 24, 2026

Hampton Inn Oxford/Conference Center
Hampton Inn New Albany

Hampton Inn New Albany

2.5 out of 5
320 Coulter Cv New Albany MS
  • 1 hour drive from University of Mississippi
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (746 reviews)
The room was clean

Reviewed on Jan 26, 2026

Hampton Inn New Albany
Holiday Inn Express New Albany by IHG

Holiday Inn Express New Albany by IHG

2.5 out of 5
300 Highway 30 New Albany MS
  • 1 hour drive from University of Mississippi
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (560 reviews)
Great breakfast. Eleanor was so friendly and helpful. Location of hotel was easy on and off interstate. Close to many things.

Reviewed on Jan 18, 2026

Holiday Inn Express New Albany by IHG
American Inn  - Pontotoc

American Inn - Pontotoc

2 out of 5
217 Highway 15 N Pontotoc MS
  • 1 hour drive from University of Mississippi
Stay at this hotel in Pontotoc. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. Popular attraction ...
7.8/10 Good! (331 reviews)
From the moment we rolled through the clean, well-kept parking lot and walkways of this little motel I knew we were going to be ok. The staff was friendly. The rooms were immaculate. There's clean in a motel of this age then there's the kind of pristine clean I saw. Every surface, every nook and ...

Reviewed on Jan 11, 2026

American Inn - Pontotoc
TownePlace Suites Oxford

TownePlace Suites Oxford

3 out of 5
105 Ed Perry Blvd Oxford MS
  • 6 min drive from University of Mississippi
Stay at this hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions The ...
9.2/10 Wonderful! (468 reviews)
Only thing I would change would be a table with USB and/or electric plugs between the 2 beds. Otherwise, it was wonderful.

Reviewed on Jan 4, 2026

TownePlace Suites Oxford
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Myrtle

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Myrtle hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Myrtle.

Choosing the right hotel in Mississippi has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Myrtle’s 605 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $82. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Myrtle hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Myrtle. No matter your reason for visiting Myrtle, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Myrtle hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Myrtle for as low as $82.

How many hotels are there in Myrtle?

With over 605 hotels in Myrtle, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $82.

How to find cheap car rentals in Myrtle?

Finding a cheap car rental deal in Myrtle is as easy as scoring cheap hotels in Myrtle. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.