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Port Wine Route

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Port Wine Route Flights as Low as $122

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Wizz Air Malta
Tue, Jul 14 - Tue, Jul 28
FCO
Fiumicino - Leonardo da Vinci Intl.
OPO
Dr. Francisco de Sa Carneiro
$122 Roundtrip, found 3 hours ago
$122
Roundtrip
found 3 hours ago
Select Wizz Air Malta flight, departing Tue, Jul 14 from Fiumicino - Leonardo da Vinci Intl. to Dr. Francisco de Sa Carneiro, returning Tue, Jul 28, priced at $122 found 3 hours ago
Iberia
Mon, Jul 13 - Tue, Jul 28
FCO
Fiumicino - Leonardo da Vinci Intl.
OPO
Dr. Francisco de Sa Carneiro
$163 Roundtrip, found 4 hours ago
$163
Roundtrip
found 4 hours ago
Select Iberia flight, departing Mon, Jul 13 from Fiumicino - Leonardo da Vinci Intl. to Dr. Francisco de Sa Carneiro, returning Tue, Jul 28, priced at $163 found 4 hours ago
Vueling Airlines
Tue, Jul 14 - Tue, Jul 28
FCO
Fiumicino - Leonardo da Vinci Intl.
OPO
Dr. Francisco de Sa Carneiro
$220 Roundtrip, found 3 hours ago
$220
Roundtrip
found 3 hours ago
Select Vueling Airlines flight, departing Tue, Jul 14 from Fiumicino - Leonardo da Vinci Intl. to Dr. Francisco de Sa Carneiro, returning Tue, Jul 28, priced at $220 found 3 hours ago
TAP Portugal
Tue, Sep 1 - Wed, Sep 16
DUS
Düsseldorf Intl.
OPO
Dr. Francisco de Sa Carneiro
$257 Roundtrip, found 4 hours ago
$257
Roundtrip
found 4 hours ago
Select TAP Portugal flight, departing Tue, Sep 1 from Düsseldorf Intl. to Dr. Francisco de Sa Carneiro, returning Wed, Sep 16, priced at $257 found 4 hours ago
Scandinavian Airlines
Fri, Aug 14 - Thu, Sep 3
DUS
Düsseldorf Intl.
OPO
Dr. Francisco de Sa Carneiro
$277 Roundtrip, found 5 hours ago
$277
Roundtrip
found 5 hours ago
Select Scandinavian Airlines flight, departing Fri, Aug 14 from Düsseldorf Intl. to Dr. Francisco de Sa Carneiro, returning Thu, Sep 3, priced at $277 found 5 hours ago
KLM
Fri, Aug 14 - Thu, Sep 3
DUS
Düsseldorf Intl.
OPO
Dr. Francisco de Sa Carneiro
$284 Roundtrip, found 5 hours ago
$284
Roundtrip
found 5 hours ago
Select KLM flight, departing Fri, Aug 14 from Düsseldorf Intl. to Dr. Francisco de Sa Carneiro, returning Thu, Sep 3, priced at $284 found 5 hours ago
TAP Portugal
Tue, Sep 1 - Wed, Sep 16
DUS
Düsseldorf Intl.
OPO
Dr. Francisco de Sa Carneiro
$285 Roundtrip, found 4 hours ago
$285
Roundtrip
found 4 hours ago
Select TAP Portugal flight, departing Tue, Sep 1 from Düsseldorf Intl. to Dr. Francisco de Sa Carneiro, returning Wed, Sep 16, priced at $285 found 4 hours ago
Air Europa
Tue, Jul 14 - Tue, Jul 28
FCO
Fiumicino - Leonardo da Vinci Intl.
OPO
Dr. Francisco de Sa Carneiro
$313 Roundtrip, found 3 hours ago
$313
Roundtrip
found 3 hours ago
Select Air Europa flight, departing Tue, Jul 14 from Fiumicino - Leonardo da Vinci Intl. to Dr. Francisco de Sa Carneiro, returning Tue, Jul 28, priced at $313 found 3 hours ago
Eurowings
Fri, Aug 14 - Fri, Sep 4
DUS
Düsseldorf Intl.
OPO
Dr. Francisco de Sa Carneiro
$322 Roundtrip, just found
$322
Roundtrip
just found
Select Eurowings flight, departing Fri, Aug 14 from Düsseldorf Intl. to Dr. Francisco de Sa Carneiro, returning Fri, Sep 4, priced at $322 just found
Air France
Tue, Sep 1 - Wed, Sep 16
DUS
Düsseldorf Intl.
OPO
Dr. Francisco de Sa Carneiro
$420 Roundtrip, found 4 hours ago
$420
Roundtrip
found 4 hours ago
Select Air France flight, departing Tue, Sep 1 from Düsseldorf Intl. to Dr. Francisco de Sa Carneiro, returning Wed, Sep 16, priced at $420 found 4 hours ago
FlexFlight
Tue, Sep 1 - Wed, Sep 16
QDU
Düsseldorf Central Train Station
OPO
Dr. Francisco de Sa Carneiro
$450 Roundtrip, found 5 hours ago
$450
Roundtrip
found 5 hours ago
Select FlexFlight flight, departing Tue, Sep 1 from Düsseldorf Central Train Station to Dr. Francisco de Sa Carneiro, returning Wed, Sep 16, priced at $450 found 5 hours ago
LOT-Polish Airlines
Fri, Aug 14 - Fri, Sep 4
DUS
Düsseldorf Intl.
OPO
Dr. Francisco de Sa Carneiro
$458 Roundtrip, just found
$458
Roundtrip
just found
Select LOT-Polish Airlines flight, departing Fri, Aug 14 from Düsseldorf Intl. to Dr. Francisco de Sa Carneiro, returning Fri, Sep 4, priced at $458 just found
Lufthansa
Tue, Jul 14 - Tue, Jul 28
FCO
Fiumicino - Leonardo da Vinci Intl.
OPO
Dr. Francisco de Sa Carneiro
$466 Roundtrip, found 3 hours ago
$466
Roundtrip
found 3 hours ago
Select Lufthansa flight, departing Tue, Jul 14 from Fiumicino - Leonardo da Vinci Intl. to Dr. Francisco de Sa Carneiro, returning Tue, Jul 28, priced at $466 found 3 hours ago
Delta
Tue, Oct 13 - Thu, Nov 5
BOS
Logan Intl.
OPO
Dr. Francisco de Sa Carneiro
$596 Roundtrip, found 4 days ago
$596
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Oct 13 from Logan Intl. to Dr. Francisco de Sa Carneiro, returning Thu, Nov 5, priced at $596 found 4 days ago
Delta
Fri, Jan 22 - Thu, Feb 4
LAX
Los Angeles Intl.
OPO
Dr. Francisco de Sa Carneiro
$784 Roundtrip, found 17 hours ago
$784
Roundtrip
found 17 hours ago
Select Delta flight, departing Fri, Jan 22 from Los Angeles Intl. to Dr. Francisco de Sa Carneiro, returning Thu, Feb 4, priced at $784 found 17 hours ago
Delta
Mon, Jul 13 - Tue, Jul 21
RDU
Raleigh - Durham Intl.
OPO
Dr. Francisco de Sa Carneiro
$925 Roundtrip, found 21 hours ago
$925
Roundtrip
found 21 hours ago
Select Delta flight, departing Mon, Jul 13 from Raleigh - Durham Intl. to Dr. Francisco de Sa Carneiro, returning Tue, Jul 21, priced at $925 found 21 hours ago

Cheap Flights to Port Wine Route

Fall in love at first flight with your vacation to Port Wine Route by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Port Wine Route on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Port Wine Route, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Port Wine Route

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Port Wine Route with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the OPO airport.

What is the cheapest month to fly to Port Wine Route?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Port Wine Route are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Port Wine Route?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Port Wine Route.

What airport is best to fly into Port Wine Route?

When you’re planning your trip to Port Wine Route, convenience is the name of the game. Luckily, Port Wine Route Vila Real Airport is nearby so you can deplane and get going on checking off everything on your Port Wine Route must-do list.

How much are flights to Port Wine Route?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Port Wine Route on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $122, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Port Wine Route?

The trick to saving a stack of cash on your flight to Port Wine Route? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $122 right now, why wait?

Port Wine Route Flight Information
Destination airport
Dr. Francisco de Sa Carneiro
Destination airport IATA code
OPO
Roundtrip price
$121

Last Minute Hotel Deals in Port Wine Route

YOTEL Porto

YOTEL Porto

4 out of 5
Rua de Gonçalo Cristóvão 206 Porto Porto
Book a stay at this business-friendly hotel in Porto. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,009 reviews)
Nice clean room

Reviewed on May 8, 2026

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YOTEL Porto
The Social Hub Porto

The Social Hub Porto

4 out of 5
Praça de Dom João 80 Porto Porto
Book a stay at this business-friendly hotel in Porto. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Popular attractions Porto Historic Center and ...
9.6/10 Exceptional! (769 reviews)
We didn’t want the full breakfast bar so we orders from the menu. They were either out of, or forgot, half our order, never brought napkins or silverware as requested, then could not do room charge. The buffet might have been good but otherwise would suggest going elsewhere for breakfast.

Reviewed on May 11, 2026

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The Social Hub Porto
Zero Box Lodge Porto

Zero Box Lodge Porto

3 out of 5
R. do Ateneu Comercial do Porto, 13 Porto Porto
Stay at this hotel in Porto. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (794 reviews)
The Staff was very helpful, the room and hotel were clean. We had a few drinks at the bar and they were great. We did not use the breakfast restaurant.

Reviewed on May 11, 2026

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Zero Box Lodge Porto
Eurostars Porto Douro

Eurostars Porto Douro

4 out of 5
Avenida Gustavo Eiffel 22 Porto
Book a stay at this business-friendly hotel in Porto. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property ...
9.4/10 Exceptional! (1,012 reviews)
Perfect location, helpful staff and nice small touches. The roof top bar was a great spot to cap the day. We would stay again. Highly recommend.

Reviewed on May 12, 2026

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Eurostars Porto Douro
Porto Palácio Hotel by The Editory

Porto Palácio Hotel by The Editory

5 out of 5
Avenida da Boavista, 1269 Porto
Book a stay at this luxury hotel in Porto. Enjoy free WiFi, 2 indoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,006 reviews)
Nice room, good breakfast, friendly and helpful staff.

Reviewed on May 7, 2026

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Porto Palácio Hotel by The Editory
Sheraton Porto Hotel & Spa

Sheraton Porto Hotel & Spa

5 out of 5
Rua Tenente Valadim, 146 Porto
Book a stay at this luxury hotel in Porto. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,003 reviews)
It was very clean

Reviewed on May 4, 2026

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Sheraton Porto Hotel & Spa
Hilton Porto Gaia

Hilton Porto Gaia

5 out of 5
Rua Serpa Pinto 124 Vila Nova de Gaia
Book a stay at this luxury hotel in Vila Nova de Gaia. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and ...
9.6/10 Exceptional! (916 reviews)
We had the most incredible stay from start to finish. We had our puppy Quincy with us and the from the moment we walked into the hotel we were treated so well by all the staff and they were so accommodating of Quincy. Room was spacious, and you couldn’t hear anyone through the walls. Bed super comfortable! ...

Reviewed on May 8, 2026

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Hilton Porto Gaia
Mercure Porto Centro Aliados

Mercure Porto Centro Aliados

4 out of 5
RUA DO BONJARDIM 95 Porto
Stay at this hotel in Porto. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff and the clean rooms in our ...
9.8/10 Exceptional! (641 reviews)
Super hotel, very well positioned. Close to the train station and all good attractions

Reviewed on May 8, 2026

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Mercure Porto Centro Aliados
See all 8,096 properties in Port Wine Route
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.