Search for Cheap Deals onHotels in Clarksdale
Choose from 55 Clarksdale Hotel Deals

Quality Inn Clarksdale
"Decided to come to home to visit family during my son's Fall break from school. The room we were given was fairly clean, outside of the carpet which looked extremely dirty. We decided to not use housekeeping services, but whenever we needed additional items the staff was extremely friendly, courteous ..."
Reviewed on Nov 4, 2026

Hampton Inn Clarksdale
"This is a well located hotel with very attentive staff and a really comfortable room. We had an awesome night sleep and a simple but good breakfast. I would definitely stay here again and recommend to others."
Reviewed on Oct 28, 2026

Americas Best Value Inn & Suites Clarksdale
"Friendly staff , helped me with everything"
Reviewed on Nov 1, 2026

Travelers Hotel

Auberge Clarksdale Blues Hostel
"Communication was excellent and the location is perfect."
Reviewed on Oct 24, 2026

Walk Downtown: Home w/ Yard in Clarksdale
"Neat old house, in a cool town if you like the blues."
Reviewed on Jun 24, 2026

High Cotton Condos
"We went for the Juke Joint and it was a perfect location. Clean. Nice rooms. Loved it! No frills, no services, just a nice apartment."
Reviewed on Apr 19, 2016

Sleek Couples Studio in Clarksdale!

Lyric Hotel West End, Trademark Collection by Wyndham

Isle Casino Hotel Lula Hotel & Casino - A Caesars Rewards Destination

Cotton House, Cleveland, a Tribute Portfolio Hotel

Motel 6 Cleveland, MS - Delta State University
Find cheap hotels in Clarksdale
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Clarksdale.
Choosing the right hotel in Mississippi has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Clarksdale’s 55 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $75. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Clarksdale hotel deals at the last minute.
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Frequently Asked Questions About Clarksdale hotels
Where can I find the best last-minute travel deals?
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How many hotels are there in Clarksdale?
With over 55 hotels in Clarksdale, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $75.
How to find cheap car rentals in Clarksdale?
Finding a cheap car rental deal in Clarksdale is as easy as scoring cheap hotels in Clarksdale. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
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