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Choose from 171 Doe Run Hotel Deals

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St Farmington MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
Baymont Inn and Suites by Wyndham Farmington, MO
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

2 out of 5
7555 State Hwy Y French Village MO
  • 3 hours drive from Mark Twain National Forest
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
10/10 Exceptional! (119 reviews)
"Limpio,muy fácil el check in cómodo y limpio."

Reviewed on Nov 2, 2026

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection

2.5 out of 5
4245 Hunt Rd Farmington MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this golf hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Crown Pointe Lodge, BW Signature Collection
Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington

2 out of 5
930 Valley Creek Dr Farmington MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Super 8 by Wyndham Farmington
Quality Inn Farmington

Quality Inn Farmington

2.5 out of 5
1400 W Liberty St Farmington MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Quality Inn Farmington
Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi

2 out of 5
820 E High St Potosi MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly motel in Potosi. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Super 8 by Wyndham Potosi
Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG

2.5 out of 5
820 Market St Farmington MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Farmington by IHG
Hampton Inn Farmington

Hampton Inn Farmington

2.5 out of 5
850 Valley Creek Dr Farmington MO
  • 2 hours drive from Mark Twain National Forest
Stay at this hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (582 reviews)
"Guests stomping around on third floor from midnight until 2am. Other than that, great stay. FD lady was really sweet. I think Karen?"

Reviewed on Oct 22, 2026

Hampton Inn Farmington
Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre

2 out of 5
8 Northwood Drive Highway 67 A Bonne Terre MO
  • 2 hours drive from Mark Twain National Forest
Stay at this motel in Bonne Terre. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Super 8 by Wyndham Bonne Terre
Madison Inn Lodge

Madison Inn Lodge

2.5 out of 5
730 Plaza Drive Fredericktown MO
  • 3 hours drive from Mark Twain National Forest
Book a stay at this business-friendly motel in Fredericktown. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in ...
7.6/10 Good! (314 reviews)
"Room was very clean . The bathroom wall had been repaired and it was done sloppy . Roughly patched and paint on floor . Staff was super friendly"

Reviewed on Oct 29, 2026

Madison Inn Lodge
Shepherd Mountain Inn

Shepherd Mountain Inn

2.5 out of 5
1321 N Hwy 21 Ironton MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Ironton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (338 reviews)
"Clean was updated and very clean Breakfast was top of the line! Staff was so friendly and helpful Very great experience stay!"

Reviewed on Oct 25, 2026

Shepherd Mountain Inn
Motel 6 Bonne Terre, MO

Motel 6 Bonne Terre, MO

2 out of 5
1017 Highway K Bonne Terre MO
  • 2 hours drive from Mark Twain National Forest
Stay at this motel in Bonne Terre. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Popular attractions Bonne Terre Mine and The Space Museum ...
Motel 6 Bonne Terre, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Doe Run

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $62. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Doe Run hotel deals at the last minute.

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Frequently Asked Questions About Doe Run hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Doe Run?

With over 171 hotels in Doe Run, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $62.

How to find cheap car rentals in Doe Run?

Finding a cheap car rental deal in Doe Run is as easy as scoring cheap hotels in Doe Run. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.