Search for Cheap Deals on
Hotels in Doe Run

Choose from 149 Doe Run Hotel Deals

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St Farmington MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,002 reviews)
Husband noted breakfast wasn’t very good. I did not have any, so I can’t really express an opinion on that. Hotel room was clean is everything I needed to get a good nights sleep

Reviewed on May 16, 2026

Baymont Inn and Suites by Wyndham Farmington, MO
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

2 out of 5
7555 State Hwy Y French Village MO
  • 3 hours drive from Mark Twain National Forest
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
9.8/10 Exceptional! (66 reviews)
We got everything we asked for.

Reviewed on May 13, 2026

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington

2 out of 5
930 Valley Creek Dr Farmington MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (644 reviews)
The room was clean and the staff was really friendly. Air conditioning worked great. It was nice to have a refrigerator, microwave and hairdryer

Reviewed on May 16, 2026

Super 8 by Wyndham Farmington
Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection

2.5 out of 5
4245 Hunt Rd Farmington MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this golf hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (623 reviews)
George at the front desk was unprofessional. I was shocked at check-in, lied to, and then made to wait for an extended amount of time. This establishment had been taken over by new owners and it has gone down hill. Dirty, filthy rooms, and horrible front desk check in. Very sad.

Reviewed on May 18, 2026

Crown Pointe Lodge, BW Signature Collection
Hampton Inn Farmington

Hampton Inn Farmington

2.5 out of 5
850 Valley Creek Dr Farmington MO
  • 2 hours drive from Mark Twain National Forest
Stay at this hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (553 reviews)
My mattress was broke and they didn't fix it. I asked for a replacement or to be switched to a diffrent room. They said they didn't have one available. I then got back to my room the second night and they texted me at 11:48 and said they could swith rooms after I was already asleep in the floor for ...

Reviewed on May 1, 2026

Hampton Inn Farmington
Quality Inn Farmington

Quality Inn Farmington

2.5 out of 5
1400 W Liberty St Farmington MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (887 reviews)
I didn't stay there the room stunk I waited for hours for them to clean it they still hadn't got it done they gave me a room key to a dirty room and I told him I wanted my money back and he said okay you can get a refund but so far I'm not getting anything and I would like to know why.. if I don't ...

Reviewed on May 17, 2026

Quality Inn Farmington
Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi

2 out of 5
820 E High St Potosi MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly motel in Potosi. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7/10 Good! (397 reviews)
Did not have breakfast at the hotel.

Reviewed on May 16, 2026

Super 8 by Wyndham Potosi
Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG

2.5 out of 5
820 Market St Farmington MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (417 reviews)
Older woman at front desk was not polite. The toilet did not work in the room and was given a plunger. Had to request a new room. Only stayed for one night and glad of that

Reviewed on Apr 28, 2026

Holiday Inn Express & Suites Farmington by IHG
Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre

2 out of 5
8 Northwood Drive Highway 67 A Bonne Terre MO
  • 2 hours drive from Mark Twain National Forest
Stay at this motel in Bonne Terre. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
7/10 Good! (559 reviews)
Very clean and the staff were friendly.

Reviewed on May 1, 2026

Super 8 by Wyndham Bonne Terre
Shepherd Mountain Inn

Shepherd Mountain Inn

2.5 out of 5
1321 N Hwy 21 Ironton MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Ironton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (312 reviews)
Breakfast was good and rooms were clean

Reviewed on May 4, 2026

Shepherd Mountain Inn
Madison Inn Lodge

Madison Inn Lodge

2.5 out of 5
730 Plaza Drive Fredericktown MO
  • 3 hours drive from Mark Twain National Forest
Book a stay at this business-friendly motel in Fredericktown. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in ...
7.6/10 Good! (301 reviews)
Room was big and clean. Bed was not comfortable.

Reviewed on Apr 25, 2026

Madison Inn Lodge
Motel 6 Bonne Terre, MO

Motel 6 Bonne Terre, MO

2 out of 5
1017 Highway K Bonne Terre MO
  • 2 hours drive from Mark Twain National Forest
Stay at this motel in Bonne Terre. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Popular attractions Bonne Terre Mine and St. Francois State ...
7.2/10 Good! (40 reviews)
Good

Reviewed on May 7, 2026

Motel 6 Bonne Terre, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Doe Run

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Doe Run hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Doe Run.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Doe Run’s 149 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $63. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Doe Run hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Doe Run. No matter your reason for visiting Doe Run, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Doe Run hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Doe Run for as low as $63.

How many hotels are there in Doe Run?

With over 149 hotels in Doe Run, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $63.

How to find cheap car rentals in Doe Run?

Finding a cheap car rental deal in Doe Run is as easy as scoring cheap hotels in Doe Run. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.