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Hotels in De Soto

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Tonight Apr 18 - Apr 19This weekend Apr 18 - Apr 20

Choose from 159 De Soto Hotel Deals

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
  • 23 min drive from Victoria Glaces Conservation Area Trailhead
The price is $183 per night from Apr 28 to Apr 29
$183
includes taxes & fees
Apr 28 - Apr 29
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
9.2/10 Wonderful! (140 reviews)
"Beautiful property. Lots to do with the kids. Would be happy to come back when I have more time to spend there."

Reviewed on Apr 11, 2025

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MO
2.5 out of 5
1625 W Columbia St, Farmington, MO
  • 1 hour drive from Victoria Glaces Conservation Area Trailhead
The price is $63 per night from Apr 27 to Apr 28
$63
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (919 reviews)
"There was not a lot of places near by to eat at."

Reviewed on Apr 15, 2025

Baymont Inn and Suites by Wyndham Farmington, MO
Pear Tree Inn St. Louis Arnold
Pear Tree Inn St. Louis Arnold
2.5 out of 5
1201 Drury Ln, Arnold, MO
  • 46 min drive from Victoria Glaces Conservation Area Trailhead
The price is $104 per night from Apr 23 to Apr 24
$104
includes taxes & fees
Apr 23 - Apr 24
Book a stay at this business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,003 reviews)
"We enjoyed our stay. Staff very friendly. Wished the bathrooms were alittle bigger."

Reviewed on Apr 12, 2025

Pear Tree Inn St. Louis Arnold
Drury Inn & Suites St. Louis Arnold
Drury Inn & Suites St. Louis Arnold
3 out of 5
3800 State Rt 141, Arnold, MO
  • 46 min drive from Victoria Glaces Conservation Area Trailhead
The price is $146 per night from Apr 27 to Apr 28
$146
includes taxes & fees
Apr 27 - Apr 28
Stay at this 3-star business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,001 reviews)
"The staff was very accommodating and so friendly!"

Reviewed on Apr 13, 2025

Drury Inn & Suites St. Louis Arnold
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
2.5 out of 5
1001 Veterans Blvd, Festus, MO
  • 21 min drive from Victoria Glaces Conservation Area Trailhead
The price is $121 per night from Apr 28 to Apr 29
$121
includes taxes & fees
Apr 28 - Apr 29
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (774 reviews)
"Room was decent. Could tell the hotel is older. Caulking in bathroom was horrible, lights in restroom flickering. Room and sheets were clean, bedframe creaked badly. Hallways smelled musty. For just a place to sleep and explore the area it did the job"

Reviewed on Apr 13, 2025

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Comfort Inn Festus - St Louis South
Comfort Inn Festus - St Louis South
2.5 out of 5
1303 Veterans Blvd, Festus, MO
  • 20 min drive from Victoria Glaces Conservation Area Trailhead
The price is $104 per night from Apr 20 to Apr 21
$104
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (802 reviews)
"Friendly staff, clean and well maintained"

Reviewed on Apr 13, 2025

Comfort Inn Festus - St Louis South
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 out of 5
1802 Gamel Cemetery Road, Festus, MO
  • 20 min drive from Victoria Glaces Conservation Area Trailhead
The price is $161 per night from Apr 27 to Apr 28
$161
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (629 reviews)
"We were in from out of state and everything went perfect!"

Reviewed on Apr 1, 2025

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Super 8 by Wyndham Farmington
Super 8 by Wyndham Farmington
2 out of 5
930 Valley Creek Dr, Farmington, MO
  • 1 hour drive from Victoria Glaces Conservation Area Trailhead
The price is $69 per night from Apr 19 to Apr 20
$69
includes taxes & fees
Apr 19 - Apr 20
Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (528 reviews)
"Clean rooms, comfortable beds, and friendly staff!!"

Reviewed on Apr 5, 2025

Super 8 by Wyndham Farmington
WoodSpring Suites St. Louis Arnold
WoodSpring Suites St. Louis Arnold
2.5 out of 5
888 Arnold Commons Dr., Arnold, MO
  • 44 min drive from Victoria Glaces Conservation Area Trailhead
The price is $88 per night from May 1 to May 2
$88
includes taxes & fees
May 1 - May 2
Stay at this hotel in Arnold. Enjoy free WiFi, free parking, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions ...
5.8/10 (392 reviews)
"All the people were friendly and kind. Been staying with for a few months."

Reviewed on Apr 15, 2025

WoodSpring Suites St. Louis Arnold
Super 8 by Wyndham Bonne Terre
Super 8 by Wyndham Bonne Terre
2 out of 5
8 Northwood Drive Highway 67 A, Bonne Terre, MO
  • 47 min drive from Victoria Glaces Conservation Area Trailhead
The price is $56 per night from Apr 27 to Apr 28
$56
includes taxes & fees
Apr 27 - Apr 28
Stay at this motel in Bonne Terre. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (456 reviews)
"Staff was very friendly"

Reviewed on Apr 9, 2025

Super 8 by Wyndham Bonne Terre
Quality Inn Farmington
Quality Inn Farmington
2.5 out of 5
1400 W Liberty St, Farmington, MO
  • 1 hour drive from Victoria Glaces Conservation Area Trailhead
The price is $61 per night from May 1 to May 2
$61
includes taxes & fees
May 1 - May 2
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (796 reviews)
Nicely renovated
"The hotel was under renovation but it didnt interrupt any part of our stay except for the Hot Tub wasn't back up and running, but wasnt a problem."

Reviewed on Apr 12, 2025

Quality Inn Farmington
Postcard Cabins St. Francois
Postcard Cabins St. Francois
2 out of 5
7555 State Hwy Y, French Village, MO
  • 53 min drive from Victoria Glaces Conservation Area Trailhead
The price is $145 per night from Apr 21 to Apr 22
$145
includes taxes & fees
Apr 21 - Apr 22
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
10/10 Exceptional! (3 reviews)
"This place made me look like a rockstar to my wife. I surprised her with a V day getaway. The cabin was awesome. We loved the view of nature from the large window. I made dinner reservations nearby at the weingarten vineyard. The hiking trail along the creek was fun. We ate breakfast right down the ..."

Reviewed on Feb 17, 2025

Postcard Cabins St. Francois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in De Soto

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $56. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great De Soto hotel deals at the last minute.

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Frequently Asked Questions About De Soto hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in De Soto?

With over 159 hotels in De Soto, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $56.

How to find cheap car rentals in De Soto?

Finding a cheap car rental deal in De Soto is as easy as scoring cheap hotels in De Soto. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.