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Hotels in De Soto

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Check Last Minute De Soto Hotel Deals

Tonight May 9 - May 10This weekend May 9 - May 11

Choose from 162 De Soto Hotel Deals

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
  • 23 min drive from Victoria Glaces Conservation Area Trailhead
The price is $183 per night from May 13 to May 14
$183
includes taxes & fees
May 13 - May 14
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
"Beautiful property. Lots to do with the kids. Would be happy to come back when I have more time to spend there."

Reviewed on Apr 11, 2025

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MO
2.5 out of 5
1625 W Columbia St, Farmington, MO
  • 1 hour drive from Victoria Glaces Conservation Area Trailhead
The price is $66 per night from May 18 to May 19
$66
includes taxes & fees
May 18 - May 19
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (935 reviews)
"Was really impressed with this place. Rooms were clean, staff was friendly and breakfast was really good. Scrambled eggs, sausage, gravy, bisquits, toast, yogurt, 3 different cereals and of course coffee."

Reviewed on May 8, 2025

Baymont Inn and Suites by Wyndham Farmington, MO
Pear Tree Inn St. Louis Arnold
Pear Tree Inn St. Louis Arnold
2.5 out of 5
1201 Drury Ln, Arnold, MO
  • 46 min drive from Victoria Glaces Conservation Area Trailhead
The price is $104 per night from May 14 to May 15
$104
includes taxes & fees
May 14 - May 15
Book a stay at this business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,001 reviews)
"Breakfast was very good. They had scrambled eggs and sausage and biscuits and gravy, along with other choices. There are also several restaurants within walking distance. Staff always had a smile and willing to help."

Reviewed on May 7, 2025

Pear Tree Inn St. Louis Arnold
Drury Inn & Suites St. Louis Arnold
Drury Inn & Suites St. Louis Arnold
3 out of 5
3800 State Rt 141, Arnold, MO
  • 46 min drive from Victoria Glaces Conservation Area Trailhead
The price is $138 per night from May 18 to May 19
$138
includes taxes & fees
May 18 - May 19
Stay at this 3-star business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,001 reviews)
"Nice surprise. First stay at a Drury. I usually stay at Hilton brands, but when I come to St. Louis, I will stay at Drury from now on."

Reviewed on May 2, 2025

Drury Inn & Suites St. Louis Arnold
Comfort Inn Festus - St Louis South
Comfort Inn Festus - St Louis South
2.5 out of 5
1303 Veterans Blvd, Festus, MO
  • 20 min drive from Victoria Glaces Conservation Area Trailhead
The price is $104 per night from May 11 to May 12
$104
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (810 reviews)
"I like the location of the hotel. It was clean and staff was friendly and helpful."

Reviewed on Apr 27, 2025

Comfort Inn Festus - St Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
2.5 out of 5
1001 Veterans Blvd, Festus, MO
  • 21 min drive from Victoria Glaces Conservation Area Trailhead
The price is $146 per night from Jun 8 to Jun 9
$146
includes taxes & fees
Jun 8 - Jun 9
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (784 reviews)
"Great place to stay"

Reviewed on May 4, 2025

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Super 8 by Wyndham Farmington
Super 8 by Wyndham Farmington
2 out of 5
930 Valley Creek Dr, Farmington, MO
  • 1 hour drive from Victoria Glaces Conservation Area Trailhead
The price is $69 per night from May 10 to May 11
$69
includes taxes & fees
May 10 - May 11
Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (534 reviews)
"The hotel was alright. The hotel needs a little TLC, but overall was fine for what we paid for. We felt safe & enjoyed the many restaurants & amenities around the hotel."

Reviewed on Apr 27, 2025

Super 8 by Wyndham Farmington
Super 8 by Wyndham Bonne Terre
Super 8 by Wyndham Bonne Terre
2 out of 5
8 Northwood Drive Highway 67 A, Bonne Terre, MO
  • 47 min drive from Victoria Glaces Conservation Area Trailhead
The price is $59 per night from May 18 to May 19
$59
includes taxes & fees
May 18 - May 19
Stay at this motel in Bonne Terre. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (460 reviews)
"Overall great stay"

Reviewed on Apr 27, 2025

Super 8 by Wyndham Bonne Terre
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 out of 5
1802 Gamel Cemetery Road, Festus, MO
  • 20 min drive from Victoria Glaces Conservation Area Trailhead
The price is $159 per night from May 18 to May 19
$159
includes taxes & fees
May 18 - May 19
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (633 reviews)
"Good location and amenities"

Reviewed on Apr 30, 2025

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Quality Inn Farmington
Quality Inn Farmington
2.5 out of 5
1400 W Liberty St, Farmington, MO
  • 1 hour drive from Victoria Glaces Conservation Area Trailhead
The price is $61 per night from Jun 1 to Jun 2
$61
includes taxes & fees
Jun 1 - Jun 2
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (800 reviews)
Nicely renovated
"The hotel was under renovation but it didnt interrupt any part of our stay except for the Hot Tub wasn't back up and running, but wasnt a problem."

Reviewed on Apr 12, 2025

Quality Inn Farmington
Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature Collection
2.5 out of 5
4245 Hunt Rd, Farmington, MO
  • 1 hour drive from Victoria Glaces Conservation Area Trailhead
The price is $137 per night from May 18 to May 19
$137
includes taxes & fees
May 18 - May 19
Book a stay at this golf hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Fun in Farmington
"I always bring my VERY healthy food with me. My room had a microwave, freezer, refrigerator and a machine to brew my tea! Perfect!"

Reviewed on May 2, 2025

Crown Pointe Lodge, BW Signature Collection
Postcard Cabins St. Francois
Postcard Cabins St. Francois
2 out of 5
7555 State Hwy Y, French Village, MO
  • 53 min drive from Victoria Glaces Conservation Area Trailhead
The price is $145 per night from May 11 to May 12
$145
includes taxes & fees
May 11 - May 12
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
10/10 Exceptional! (5 reviews)
A peaceful retreat
"The cabin was beautiful and so peaceful. The cabins are spaced nicely so you almost feel like you are the only ones there until you walk the grounds. Would stay again!"

Reviewed on Apr 30, 2025

Postcard Cabins St. Francois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in De Soto

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great De Soto hotel deals at the last minute.

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Frequently Asked Questions About De Soto hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in De Soto?

With over 162 hotels in De Soto, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $59.

How to find cheap car rentals in De Soto?

Finding a cheap car rental deal in De Soto is as easy as scoring cheap hotels in De Soto. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.