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Featured De Soto Resorts & Hotels with Spas
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
4800 U.S. Highway 67, De Soto, MO
Fully refundable
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Points of Interests in De Soto
- Hotels near Mississippi River
- Hotels near Meramec State Park
- Hotels near Meramec River
- Hotels near Bonne Terre Mine
- Hotels near St. Francois State Park
- Hotels near Big River
- Hotels near St. Joe State Park
- Hotels near Hawn State Park
- Hotels near Crown Pointe Golf Club
- Hotels near Pickle Springs Natural Area
- Hotels near Villa Antonio Winery
Cities near De Soto
- Ste Genevieve Hotels (29.75 mi)
- Ozarks Hotels (126.1 mi)
- Fenton Hotels (26.47 mi)
- Farmington Hotels (25.8 mi)
- Arnold Hotels (22.42 mi)
- Southern Illinois Hotels (95.67 mi)
- Eureka Hotels (25.38 mi)
- Sullivan Hotels (33.17 mi)
- Festus Hotels (10.4 mi)
- St. Clair Hotels (26.71 mi)
- Pacific Hotels (25.71 mi)
- Waterloo Hotels (25.83 mi)
- Potosi Hotels (18.89 mi)
- Union Hotels (32.61 mi)
- Bourbon Hotels (37.42 mi)
- Bonne Terre Hotels (14.8 mi)
- Imperial Hotels (18.56 mi)
- Tesson Ferry Hotels (26.35 mi)
- Park Hills Hotels (19.8 mi)
- Pevely Hotels (13.09 mi)
Car Rentals Near De Soto
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- Car rentals in Union
- Car rentals in Bourbon
- Car rentals in Bonne Terre
Top Spa Resort Destinations
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Top Booked Hotels in De Soto
- Baymont Inn and Suites by Wyndham Farmington, MO
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
- WoodSpring Suites St. Louis Arnold
- Super 8 by Wyndham Farmington
- Quality Inn & Suites Arnold - St Louis
- Comfort Inn Festus - St Louis South
- Quality Inn Farmington
- Hampton Inn Farmington