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Featured De Soto Family Hotels
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
4800 U.S. Highway 67, De Soto, MO
Fully refundable
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in De Soto
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
4800 U.S. Highway 67, De Soto, MO
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
Top Points of Interests in De Soto
- Hotels near Mississippi River
- Hotels near Meramec State Park
- Hotels near Bonne Terre Mine
- Hotels near St. Joe State Park
- Hotels near Meramec River
- Hotels near Pickle Springs Natural Area
- Hotels near Hawn State Park
- Hotels near St. Francois State Park
- Hotels near Crown Pointe Golf Club
- Hotels near Washington State Park
- Hotels near Missouri Mines State Historic Site
- Hotels near Villa Antonio Winery
Cities near De Soto
- Ste Genevieve Hotels (29.75 mi)
- Ozarks Hotels (126.1 mi)
- Farmington Hotels (25.8 mi)
- Fenton Hotels (26.47 mi)
- Southern Illinois Hotels (95.67 mi)
- Arnold Hotels (22.42 mi)
- Eureka Hotels (25.38 mi)
- Sullivan Hotels (33.17 mi)
- Festus Hotels (10.4 mi)
- St. Clair Hotels (26.71 mi)
- Pacific Hotels (25.71 mi)
- Bourbon Hotels (37.42 mi)
- Potosi Hotels (18.89 mi)
- Union Hotels (32.61 mi)
- Waterloo Hotels (25.83 mi)
- Bonne Terre Hotels (14.8 mi)
- Tesson Ferry Hotels (26.35 mi)
- Imperial Hotels (18.56 mi)
- Park Hills Hotels (19.8 mi)
- Pevely Hotels (13.09 mi)
Car Rentals Near De Soto
- Car rentals in Ste Genevieve
- Car rentals in Ozarks
- Car rentals in Farmington
- Car rentals in Fenton
- Car rentals in Southern Illinois
- Car rentals in Arnold
- Car rentals in Eureka
- Car rentals in Sullivan
- Car rentals in Festus
- Car rentals in St. Clair
- Car rentals in Pacific
- Car rentals in Bourbon
- Car rentals in Potosi
- Car rentals in Union
- Car rentals in Waterloo
- Car rentals in Bonne Terre
Top Family Hotel Destinations
- Las Vegas Family Hotels
- Arcade Family Hotels
- Branson Family Hotels
- Biloxi Family Hotels
- Ocean City Family Hotels
- Orlando Family Hotels
- Buffalo Family Hotels
- Reno Family Hotels
- Colorado Springs Family Hotels
- Phoenix Family Hotels
- Niagara Falls Family Hotels
- New York Family Hotels
- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in De Soto
- Baymont Inn and Suites by Wyndham Farmington, MO
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
- WoodSpring Suites St. Louis Arnold
- Super 8 by Wyndham Farmington
- Comfort Inn Festus - St Louis South
- Quality Inn Farmington
- Super 8 by Wyndham Bonne Terre
- Hampton Inn Farmington
- Super 8 by Wyndham Potosi
- Quality Inn Festus
- Crown Pointe Lodge, BW Signature Collection