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De Soto

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De Soto Flights as Low as $73

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Feb 12 - Sat, Feb 15
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$73 Roundtrip, found 4 days ago
$73
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Feb 12 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Feb 15, priced at $73 found 4 days ago
Frontier Airlines
Sat, Jan 11 - Tue, Jan 14
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$116 Roundtrip, found 2 days ago
$116
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Jan 11 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Tue, Jan 14, priced at $116 found 2 days ago
Frontier Airlines
Thu, Jan 9 - Mon, Jan 13
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$118 Roundtrip, found 20 hours ago
$118
Roundtrip
found 20 hours ago
Select Frontier Airlines flight, departing Thu, Jan 9 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Mon, Jan 13, priced at $118 found 20 hours ago
Frontier Airlines
Sat, Feb 1 - Mon, Feb 10
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$118 Roundtrip, found 19 hours ago
$118
Roundtrip
found 19 hours ago
Select Frontier Airlines flight, departing Sat, Feb 1 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Mon, Feb 10, priced at $118 found 19 hours ago
Frontier Airlines
Sat, Jan 11 - Sun, Jan 12
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$128 Roundtrip, found 1 day ago
$128
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Jan 11 from San Antonio Intl. to Lambert-St. Louis Intl., returning Sun, Jan 12, priced at $128 found 1 day ago
Frontier Airlines
Wed, Feb 12 - Fri, Feb 21
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$148 Roundtrip, found 1 day ago
$148
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Feb 12 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Fri, Feb 21, priced at $148 found 1 day ago
United
Tue, Feb 4 - Tue, Feb 11
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$196 Roundtrip, found 19 hours ago
$196
Roundtrip
found 19 hours ago
Select United flight, departing Tue, Feb 4 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Feb 11, priced at $196 found 19 hours ago
Delta
Wed, Jan 8 - Mon, Jan 13
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$198 Roundtrip, found 2 days ago
$198
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Jan 8 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Mon, Jan 13, priced at $198 found 2 days ago
American Airlines
Wed, Jan 8 - Mon, Jan 13
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$201 Roundtrip, found 2 days ago
$201
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Jan 8 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Mon, Jan 13, priced at $201 found 2 days ago
Spirit Airlines
Wed, Jan 8 - Tue, Jan 14
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$233 Roundtrip, found 2 days ago
$233
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Wed, Jan 8 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Tue, Jan 14, priced at $233 found 2 days ago
American Airlines
Fri, Jun 6 - Tue, Jul 1
SJU
Luis Munoz Marin Intl.
STL
Lambert-St. Louis Intl.
$300 Roundtrip, found 17 hours ago
$300
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Fri, Jun 6 from Luis Munoz Marin Intl. to Lambert-St. Louis Intl., returning Tue, Jul 1, priced at $300 found 17 hours ago
Delta
Tue, Dec 31 - Wed, Jan 8
ABQ
Albuquerque Intl. Sunport
STL
Lambert-St. Louis Intl.
$301 Roundtrip, found 1 day ago
$301
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Dec 31 from Albuquerque Intl. Sunport to Lambert-St. Louis Intl., returning Wed, Jan 8, priced at $301 found 1 day ago
Alaska Airlines
Fri, Jan 24 - Tue, Jan 28
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$310 Roundtrip, found 2 days ago
$310
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Fri, Jan 24 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Tue, Jan 28, priced at $310 found 2 days ago
Delta
Tue, Jan 7 - Mon, Jan 13
GEG
Spokane Intl.
STL
Lambert-St. Louis Intl.
$316 Roundtrip, found 19 hours ago
$316
Roundtrip
found 19 hours ago
Select Delta flight, departing Tue, Jan 7 from Spokane Intl. to Lambert-St. Louis Intl., returning Mon, Jan 13, priced at $316 found 19 hours ago
Delta
Tue, Feb 11 - Wed, Feb 12
DAL
Love Field
STL
Lambert-St. Louis Intl.
$372 Roundtrip, found 5 days ago
$372
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Feb 11 from Love Field to Lambert-St. Louis Intl., returning Wed, Feb 12, priced at $372 found 5 days ago
United
Thu, Jun 5 - Thu, Jun 26
BQN
Rafael Hernandez
STL
Lambert-St. Louis Intl.
$519 Roundtrip, found 17 hours ago
$519
Roundtrip
found 17 hours ago
Select United flight, departing Thu, Jun 5 from Rafael Hernandez to Lambert-St. Louis Intl., returning Thu, Jun 26, priced at $519 found 17 hours ago

Cheap Flights to De Soto

Fall in love at first flight with your vacation to De Soto by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to De Soto on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in De Soto, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to De Soto

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to De Soto with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to De Soto?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to De Soto are in February, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to De Soto?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to De Soto.

What airport is best to fly into De Soto?

When you’re planning your trip to De Soto, convenience is the name of the game. Luckily, De Soto Spirit of St. Louis Airport is nearby so you can deplane and get going on checking off everything on your De Soto must-do list.

How much are flights to De Soto?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to De Soto on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $73, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to De Soto?

The trick to saving a stack of cash on your flight to De Soto? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $73 right now, why wait?

De Soto Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$73

Last Minute Hotel Deals in De Soto

Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
The price is $183 per night from Jan 2 to Jan 3
$183
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
9.2/10 Wonderful! (137 reviews)
"Staff friendly. Unit was spotless"

Reviewed on Nov 15, 2024

Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MO
2.5 out of 5
1625 W Columbia St, Farmington, MO
The price is $59 per night from Jan 5 to Jan 6
$59
includes taxes & fees
Jan 5 - Jan 6, 2025
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (817 reviews)
"I don't really like being right next to people but it's a hotel and i love the poolside rooms only, i just wish i could stay more working for AI to get work done on secure location"

Reviewed on Dec 12, 2024

Baymont Inn and Suites by Wyndham Farmington, MO
Pear Tree Inn St. Louis Arnold
Pear Tree Inn St. Louis Arnold
2.5 out of 5
1201 Drury Ln, Arnold, MO
The price is $99 per night from Dec 28 to Dec 29
$99
includes taxes & fees
Dec 28 - Dec 29
Book a stay at this business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,002 reviews)
Very good as always!
"Everything and everyone was very good, as always! I think there might have been a breakdown in communication since my room wasn’t refreshed during my stay, but I’m sure it would have been quickly addressed if I had brought it to their attention!v"

Reviewed on Dec 18, 2024

Pear Tree Inn St. Louis Arnold
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
2.5 out of 5
1001 Veterans Blvd, Festus, MO
The price is $96 per night from Dec 26 to Dec 27
$96
includes taxes & fees
Dec 26 - Dec 27
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (719 reviews)
"was concerned about safety with the homeless people hanging around the hotel. Even had a homeless person approach us and ask for handouts."

Reviewed on Dec 21, 2024

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Drury Inn & Suites St. Louis Arnold
Drury Inn & Suites St. Louis Arnold
3 out of 5
3800 State Rt 141, Arnold, MO
The price is $130 per night from Dec 29 to Dec 30
$130
includes taxes & fees
Dec 29 - Dec 30
Stay at this 3-star business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,001 reviews)
"Always enjoy Drury Inn. This one is close to family and the breakfast and happy hour deal is amazing. Appreciate the very friendly staff as well. Feels like staying with friends!"

Reviewed on Dec 15, 2024

Drury Inn & Suites St. Louis Arnold
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
2.5 out of 5
1802 Gamel Cemetery Road, Festus, MO
The price is $142 per night from Jan 4 to Jan 5
$142
includes taxes & fees
Jan 4 - Jan 5, 2025
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (603 reviews)
"Very clean, nice staff, and just what we needed during a difficult time facing a family members death."

Reviewed on Dec 21, 2024

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
Comfort Inn Festus - St Louis South
Comfort Inn Festus - St Louis South
2.5 out of 5
1303 Veterans Blvd, Festus, MO
The price is $97 per night from Jan 2 to Jan 3
$97
includes taxes & fees
Jan 2 - Jan 3, 2025
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (768 reviews)
"Looks fine"

Reviewed on Dec 3, 2024

Comfort Inn Festus - St Louis South
WoodSpring Suites St. Louis Arnold
WoodSpring Suites St. Louis Arnold
2.5 out of 5
888 Arnold Commons Dr., Arnold, MO
The price is $82 per night from Dec 25 to Dec 26
$82
includes taxes & fees
Dec 25 - Dec 26
Stay at this hotel in Arnold. Enjoy free WiFi, free parking, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions ...
5.8/10 (379 reviews)
"Staff very friendly and helpful."

Reviewed on Dec 14, 2024

WoodSpring Suites St. Louis Arnold
See all 143 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.