Hotels Near
Downtown Gainesville

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Featured Downtown Gainesville Hotels

Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown

3 out of 5
212 SE 1ST STREET, Gainesville FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,100 reviews)
Great

Reviewed on Dec 5, 2025

Hyatt Place Gainesville Downtown
Hampton Inn & Suites Gainesville-Downtown

Hampton Inn & Suites Gainesville-Downtown

3 out of 5
101 SE 1st Ave Gainesville FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our ...
8.4/10 Very Good! (1,001 reviews)
Staff was nice and room were clean.

Reviewed on Dec 3, 2025

Hampton Inn & Suites Gainesville-Downtown
DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

4 out of 5
3726 Sw 40th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Gainesville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,017 reviews)
Great value

Reviewed on Dec 2, 2025

DoubleTree by Hilton Gainesville
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

2.5 out of 5
3905 Sw 43Rd St Gainesville FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,793 reviews)
Perfect stay will be back.

Reviewed on Nov 30, 2025

HOM Hotel Gainesville, SureStay Collection by Best Western
Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida

3 out of 5
1514 Southwest 14th Street Gainesville FL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Gainesville. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful staff in our ...
9.2/10 Wonderful! (1,268 reviews)
Get service and location to UF. Not the cheapest option but worth the price

Reviewed on Nov 30, 2025

Hotel Eleo at the University of Florida
La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville

3 out of 5
908 NW 69 Terrace Gainesville FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,116 reviews)
Overall experience was great from check in to check out! Property as well as room was very clean. Lots of restaurants in the area. Close to all medical facilities.

Reviewed on Dec 2, 2025

La Quinta by Wyndham Gainesville
Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville

3.5 out of 5
1714 SW 34th St Gainesville FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Gainesville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
Great location though the pillows were too soft for my liking

Reviewed on Dec 2, 2025

Hilton University of Florida Conference Center Gainesville
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

2.5 out of 5
4110 SW 40th Boulevard Gainesville FL
Fully refundable
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,024 reviews)
Changed our room, when there was water on the bathroom floor.

Reviewed on Dec 2, 2025

Sleep Inn & Suites University/Shands
Best Western Gateway Grand

Best Western Gateway Grand

3 out of 5
4200 NW 97th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.6/10 Excellent! (1,348 reviews)
Great

Reviewed on Dec 5, 2025

Best Western Gateway Grand
Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL

3 out of 5
4015 Sw 43rd St Gainesville FL
Fully refundable
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,614 reviews)
Excelente

Reviewed on Dec 4, 2025

Country Inn & Suites by Radisson, Gainesville, FL
Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

2.5 out of 5
3500 Southwest 42nd St Gainesville FL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Gainesville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,228 reviews)
Clean room very helpful staff

Reviewed on Dec 1, 2025

Red Roof Inn PLUS+ Gainesville
Comfort Inn University

Comfort Inn University

2.5 out of 5
3440 SW 40th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,000 reviews)
Front desk woman was great. Terrific night of rest after a long day in the car.

Reviewed on Dec 4, 2025

Comfort Inn University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Downtown Gainesville

Gainesville is a city that has a lot going on, but you have your sights set on Downtown Gainesville. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Downtown Gainesville has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Downtown Gainesville hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Gainesville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Downtown Gainesville underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Downtown Gainesville city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Downtown Gainesville cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Downtown Gainesville at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $78
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Downtown Gainesville hotel you want, book it, and never look back. Because your great escape is ahead of you.