Hotels Near
Little Rock Medical District

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Featured Little Rock Medical District Hotels

Guest Inn & Suites - Midtown Medical Center

Guest Inn & Suites - Midtown Medical Center

3 out of 5
301 S. University Ave. Little Rock AR
Fully refundableReserve now, pay when you stay
Stay at this hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (876 reviews)
Absolutely

Reviewed on Dec 22, 2025

Guest Inn & Suites - Midtown Medical Center
Four Points by Sheraton Little Rock Midtown

Four Points by Sheraton Little Rock Midtown

3.5 out of 5
925 S University Ave Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (826 reviews)
Clean room, friendly staff, and would highly recommend staying again.

Reviewed on Dec 31, 2025

Four Points by Sheraton Little Rock Midtown
Staybridge Suites Little Rock - Medical Center by IHG

Staybridge Suites Little Rock - Medical Center by IHG

3 out of 5
1020 S University Ave Little Rock AR
Fully refundable
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,002 reviews)
This is a cross country journey, day 6. The best suite yet. Spacious, clean, and functional. I am at a competitor suite tonight and I miss your’s already

Reviewed on Jan 1, 2026

Staybridge Suites Little Rock - Medical Center by IHG
Home2 Suites By Hilton Little Rock Midtown/Medical Center

Home2 Suites By Hilton Little Rock Midtown/Medical Center

3 out of 5
6300 District Ave Little Rock AR
Fully refundableReserve now, pay when you stay
Stay at this hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Simmons Bank Arena and Park Plaza Mall are located ...
9.4/10 Exceptional! (83 reviews)
The hot breakfast mostly consisted of premade items in a plexiglass box. Egg items looked like they were made in a factory, and heated up at the hotel. Waffle batter device difficult to operate and UNSANITARY. Raw Batter drips and slops under the dispensing point because it is difficult to cleanly ...

Reviewed on Jan 1, 2026

Home2 Suites By Hilton Little Rock Midtown/Medical Center
Garden Inn and Suites Little Rock

Garden Inn and Suites Little Rock

2 out of 5
3801 W. 8th St. Little Rock AR
Stay at this motel in Little Rock. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (628 reviews)
Was actually quiet even tho right by the freeway. Getting a make over it seemed new bathrooms was really nice

Reviewed on Nov 20, 2025

Garden Inn and Suites Little Rock
Days Inn by Wyndham Little Rock/Medical Center

Days Inn by Wyndham Little Rock/Medical Center

2.5 out of 5
901 Fair Park Blvd Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Simmons Bank Arena and Little ...
6/10 (1,005 reviews)
coffie pot missing parts

Reviewed on Dec 31, 2025

Days Inn by Wyndham Little Rock/Medical Center
Spark by Hilton Little Rock West

Spark by Hilton Little Rock West

3 out of 5
9 Crossings Court Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,028 reviews)
Was very pleasantly surprised on how nice and specious the room was. Breakfast was really good and offered a lot more than most.

Reviewed on Jan 2, 2026

Spark by Hilton Little Rock West
Comfort Inn & Suites Presidential - Downtown Little Rock

Comfort Inn & Suites Presidential - Downtown Little Rock

3 out of 5
707 Interstate 30 Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,290 reviews)
Love it!!!

Reviewed on Jan 2, 2026

Comfort Inn & Suites Presidential - Downtown Little Rock
Embassy Suites Little Rock

Embassy Suites Little Rock

3.5 out of 5
11301 Financial Centre Pkwy Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast ...
8/10 Very Good! (1,009 reviews)
Out stay was great

Reviewed on Dec 31, 2025

Embassy Suites Little Rock
Wyndham Riverfront Little Rock

Wyndham Riverfront Little Rock

3.5 out of 5
2 Riverfront Pl North Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in North Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,704 reviews)
Great restaurant and hospitality

Reviewed on Jan 2, 2026

Wyndham Riverfront Little Rock
Courtyard by Marriott Little Rock West

Courtyard by Marriott Little Rock West

3 out of 5
10900 Financial Centre Pkwy Little Rock AR
Book a stay at this business-friendly hotel in Little Rock. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (288 reviews)
I did not have breakfast. Unreal that this is an option.

Reviewed on Jan 2, 2026

Courtyard by Marriott Little Rock West
Little Rock Marriott

Little Rock Marriott

4 out of 5
3 Statehouse Plaza Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
9/10 Wonderful! (1,001 reviews)
Staff friendly efficient

Reviewed on Jan 2, 2026

Little Rock Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Little Rock Medical District

Little Rock is a city that has a lot going on, but you have your sights set on Little Rock Medical District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Little Rock Medical District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Little Rock Medical District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Little Rock so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Little Rock Medical District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Little Rock Medical District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Little Rock Medical District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Little Rock Medical District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $63
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Little Rock Medical District hotel you want, book it, and never look back. Because your great escape is ahead of you.