Hotels Near
Little Rock Medical District

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Featured Little Rock Medical District Hotels

Guest Inn & Suites - Midtown Medical Center

Guest Inn & Suites - Midtown Medical Center

3 out of 5
301 S. University Ave. Little Rock AR
Fully refundableReserve now, pay when you stay
Stay at this hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (859 reviews)
we tried to talk to the housekeeper in the hall wanted more towels and coffee but we could not communicate with her. no speak english. had to wait and the front dest staff member had to get what we need. the room was not entered by housekeeper beds not made trash not carried out. other than that ...

Reviewed on Nov 25, 2025

Guest Inn & Suites - Midtown Medical Center
Four Points by Sheraton Little Rock Midtown

Four Points by Sheraton Little Rock Midtown

3.5 out of 5
925 S University Ave Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (813 reviews)
The staff were very nice. Rooms nice and clean

Reviewed on Nov 22, 2025

Four Points by Sheraton Little Rock Midtown
Staybridge Suites Little Rock - Medical Center by IHG

Staybridge Suites Little Rock - Medical Center by IHG

3 out of 5
1020 S University Ave Little Rock AR
Fully refundable
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,004 reviews)
Clean, well-stocked, spacious suite, courteous staff, delicious breakfast. We will stay here again. The elevators had some problems but one was always working.

Reviewed on Nov 24, 2025

Staybridge Suites Little Rock - Medical Center by IHG
Days Inn by Wyndham Little Rock/Medical Center

Days Inn by Wyndham Little Rock/Medical Center

2.5 out of 5
901 Fair Park Blvd Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Simmons Bank Arena and Little ...
6/10 (1,002 reviews)
Staff was friendly and the room was clean. Great location for medical procedure scheduled just eight minutes away. Price was very reasonable, and hotel is pet friendly, so we were able to bring our dog❤️

Reviewed on Nov 20, 2025

Days Inn by Wyndham Little Rock/Medical Center
Home2 Suites By Hilton Little Rock Midtown/Medical Center

Home2 Suites By Hilton Little Rock Midtown/Medical Center

3 out of 5
6300 District Ave Little Rock AR
Fully refundableReserve now, pay when you stay
Stay at this hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Simmons Bank Arena and Park Plaza Mall are located ...
9.4/10 Exceptional! (76 reviews)
Rooms need more insulation, lots of surround noise ! From the rooms above !

Reviewed on Nov 20, 2025

Home2 Suites By Hilton Little Rock Midtown/Medical Center
Garden Inn and Suites Little Rock

Garden Inn and Suites Little Rock

2 out of 5
3801 W. 8th St. Little Rock AR
Stay at this motel in Little Rock. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (625 reviews)
Was actually quiet even tho right by the freeway. Getting a make over it seemed new bathrooms was really nice

Reviewed on Nov 20, 2025

Garden Inn and Suites Little Rock
Spark by Hilton Little Rock West

Spark by Hilton Little Rock West

3 out of 5
9 Crossings Court Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,030 reviews)
Very clean but not very quiet because neighbor had a whining barking dog.

Reviewed on Nov 27, 2025

Spark by Hilton Little Rock West
Comfort Inn & Suites Presidential - Downtown Little Rock

Comfort Inn & Suites Presidential - Downtown Little Rock

3 out of 5
707 Interstate 30 Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,224 reviews)
Fast and easy.

Reviewed on Nov 26, 2025

Comfort Inn & Suites Presidential - Downtown Little Rock
Wyndham Riverfront Little Rock

Wyndham Riverfront Little Rock

3.5 out of 5
2 Riverfront Pl North Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in North Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,683 reviews)
Awesome manager checked me in, the breakfast crew was awesome, and the room was exceptionally clean and most comfortable bed! If ever in the area again, will definitely stay again.

Reviewed on Nov 27, 2025

Wyndham Riverfront Little Rock
Courtyard by Marriott Little Rock West

Courtyard by Marriott Little Rock West

3 out of 5
10900 Financial Centre Pkwy Little Rock AR
Book a stay at this business-friendly hotel in Little Rock. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (261 reviews)
The staff was very professional and nice

Reviewed on Nov 23, 2025

Courtyard by Marriott Little Rock West
Hampton Inn & Suites Little Rock-Downtown

Hampton Inn & Suites Little Rock-Downtown

2.5 out of 5
320 River Market Avenue Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,004 reviews)
Staff was so friendly and welcoming. I wish I would have gotten her name.

Reviewed on Nov 27, 2025

Hampton Inn & Suites Little Rock-Downtown
Little Rock Marriott

Little Rock Marriott

4 out of 5
3 Statehouse Plaza Little Rock AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
9/10 Wonderful! (1,007 reviews)
Rooms were clean, bed comfy & friendly staff. Would definitely stay here again.

Reviewed on Nov 23, 2025

Little Rock Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Little Rock Medical District

Little Rock is a city that has a lot going on, but you have your sights set on Little Rock Medical District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Little Rock Medical District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Little Rock Medical District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Little Rock so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Little Rock Medical District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Little Rock Medical District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Little Rock Medical District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Little Rock Medical District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $55
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Little Rock Medical District hotel you want, book it, and never look back. Because your great escape is ahead of you.