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Featured Main Street Hyannis Resorts & Hotels with Spas
Hyannis Plaza Hotel
662 Main Street, Hyannis, MA
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Hyannis. Enjoy free parking, an outdoor pool, and a 24-hour front desk. Popular attractions Wackenhammer's Clockwork Arcade ...
Comfort Inn Hyannis - Cape Cod
259 Main Street, Hyannis, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Hyannis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Hotel Options in Main Street Hyannis
- Hotels with a Pool in Main Street Hyannis
- Historic Hotels in Main Street Hyannis
- Hotels with Free Parking in Main Street Hyannis
- Beach Hotels in Main Street Hyannis
- Family Hotels in Main Street Hyannis
- Winery Hotels in Main Street Hyannis
- Luxury Hotels in Main Street Hyannis
- Romantic Hotels in Main Street Hyannis
- Hotel Wedding Venues in Main Street Hyannis
- Hotels with Hot Tubs in Main Street Hyannis
Top Points of Interests in Main Street Hyannis
- Hotels near John F. Kennedy Hyannis Museum
- Hotels near Cape Cod Baseball Hall of Fame
- Hotels near Wackenhammer's Clockwork Arcade
- Hotels near Cape Cod National Seashore
- Hotels near Hyannis Harbor
- Hotels near Nauset Beach
- Hotels near Mayflower Beach
- Hotels near Falmouth Heights Beach
- Hotels near Cape Cod Inflatable Park
- Hotels near Craigville Beach
- Hotels near Ocean Edge Golf Club
- Hotels near Old Silver Beach
- Hotels near Seagull Beach
- Hotels near Cape Cod Melody Tent
- Hotels near Harwich Port
- Hotels near Massachusetts Maritime Academy
- Hotels near Island Queen Ferry
- Hotels near Skaket Beach
- Hotels near Mashpee Commons
- Hotels near West Dennis Beach
Cities near Main Street Hyannis
- Cape Cod Hotels (2.47 mi)
- East Sandwich Hotels (9.82 mi)
- Martha's Vineyard Hotels (26.53 mi)
- Hyannis Hotels (0.08 mi)
- Plymouth Hotels (28.75 mi)
- Chatham Hotels (16.72 mi)
- Dennis Port Hotels (7.99 mi)
- Falmouth Hotels (18.52 mi)
- Brewster Hotels (12.72 mi)
- West Yarmouth Hotels (2.18 mi)
- East Falmouth Hotels (15.11 mi)
- Edgartown Hotels (21.74 mi)
- Wellfleet Hotels (23.17 mi)
- North Chatham Hotels (17.33 mi)
- South Yarmouth Hotels (4.61 mi)
- Oak Bluffs Hotels (19.87 mi)
- Eastham Hotels (20.09 mi)
- Orleans Hotels (17.85 mi)
- Dennis Hotels (7.34 mi)
- Sandwich Hotels (13.11 mi)
Car Rentals Near Main Street Hyannis
- Car rentals in Cape Cod
- Car rentals in East Sandwich
- Car rentals in Martha's Vineyard
- Car rentals in Hyannis
- Car rentals in Plymouth
- Car rentals in Chatham
- Car rentals in Dennis Port
- Car rentals in Falmouth
- Car rentals in Brewster
- Car rentals in West Yarmouth
- Car rentals in East Falmouth
- Car rentals in Edgartown
- Car rentals in Wellfleet
- Car rentals in North Chatham
- Car rentals in South Yarmouth
- Car rentals in Oak Bluffs
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
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- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
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- Waco Spa Hotels
Top Booked Hotels in Main Street Hyannis
- Americas Best Value Inn & Suites Hyannis Cape Cod
- Cape Cod Inn
- Margaritaville Resort Cape Cod
- Bayside Resort Hotel
- Chatham Bars Inn
- Sea Crest Beach Resort
- Anchor In Distinctive Waterfront Lodging
- Fairfield Inn & Suites by Marriott Cape Cod Hyannis
- Cape Sands Inn
- Sandwich Inn and Suites
- The Mansion at Ocean Edge