Hotels Near
Medical District

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Featured Medical District Hotels

Courtyard Marriott Greenville
Courtyard Marriott Greenville
3 out of 5
2225 Stantonsburg Rd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (862 reviews)
Best In Class Greenville
"Excellent condition, kind staff, convenient and quiet!"

Reviewed on Jul 1, 2025

Courtyard Marriott Greenville
Microtel Inn & Suites by Wyndham Greenville/University Medic
Microtel Inn & Suites by Wyndham Greenville/University Medic
2 out of 5
450 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (1,002 reviews)
"Clean, convenient"

Reviewed on Jun 22, 2025

Microtel Inn & Suites by Wyndham Greenville/University Medic
Holiday Inn Greenville by IHG
Holiday Inn Greenville by IHG
3 out of 5
203 Greenville Blvd SW, Greenville, NC
Fully refundable
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,008 reviews)
"The staff was A1. Very knowledgeable of the area . Very safe environment. The breakfast was great . Highly recommended"

Reviewed on Jul 4, 2025

Holiday Inn Greenville by IHG
Country Inn & Suites by Radisson, Greenville, NC
Country Inn & Suites by Radisson, Greenville, NC
3 out of 5
3900 S Memorial Dr, Winterville, NC
Fully refundable
Stay at this 3-star business-friendly hotel in Winterville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (747 reviews)
"Clean and quite"

Reviewed on Jun 29, 2025

Country Inn & Suites by Radisson, Greenville, NC
Quality Inn Greenville near University
Quality Inn Greenville near University
2.5 out of 5
821 Memorial Dr, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (955 reviews)
"Breakfast was simple but good enough. Several options to pick from. The AC worked great and wasn’t loud. The towels and linens were clean and we had plenty. They cleaned our room after night one and I thought that was only by request so that was a pleasant surprise. We didn’t get the Wi-Fi password ..."

Reviewed on Jun 26, 2025

Quality Inn Greenville near University
Baymont by Wyndham Greenville
Baymont by Wyndham Greenville
2.5 out of 5
3439 S Memorial Drive, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.4/10 (1,002 reviews)
Don't over look this property
"My stay at the hotel was nice the workers was friendly the pool was open and clean."

Reviewed on Jun 29, 2025

Baymont by Wyndham Greenville
Best Western Plus Suites-Greenville
Best Western Plus Suites-Greenville
2.5 out of 5
2310 Greenville Boulevard NE, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,004 reviews)
"Very nice people and area. The room was clean and very comfortable. Would like to return again to really check out the city."

Reviewed on Jul 5, 2025

Best Western Plus Suites-Greenville
Hampton Inn Greenville
Hampton Inn Greenville
2.5 out of 5
305 Greenville Blvd Sw, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions University Commons and Bowlero East Carolina are located ...
8.8/10 Excellent! (512 reviews)
"My room was by the window over looking the street from the side…nice little view"

Reviewed on Jun 19, 2025

Hampton Inn Greenville
Comfort Inn & Suites Greenville Near Convention Center
Comfort Inn & Suites Greenville Near Convention Center
2.5 out of 5
3212 S Memorial Dr, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (326 reviews)
"Very much the same as most hotels in this category. Breakfast was standard. Room was standard. Coffee was standard."

Reviewed on Jul 3, 2025

Comfort Inn & Suites Greenville Near Convention Center
Homewood Suites By Hilton Greenville, NC
Homewood Suites By Hilton Greenville, NC
3 out of 5
420 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star golf hotel in Greenville. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (251 reviews)
"Great room"

Reviewed on Jul 7, 2025

Homewood Suites By Hilton Greenville, NC
Fairfield Inn & Suites by Marriott Greenville
Fairfield Inn & Suites by Marriott Greenville
2.5 out of 5
908 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (416 reviews)
"Nice hotel, staff and pool"

Reviewed on Jun 23, 2025

Fairfield Inn & Suites by Marriott Greenville
Hampton Inn Washington
Hampton Inn Washington
2.5 out of 5
2085 W 15th St, Washington, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Washington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (592 reviews)
"Its location from the main highway was ideal. It felt like a safe location. The staff were super friendly. Other guests were friendly and we exchanged several pleasantries with people just wanting to say, "Hello" - that is not normal where we are from, so it's odd being around nice people. Royal ..."

Reviewed on Jul 3, 2025

Hampton Inn Washington
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Medical District

Greenville is a city that has a lot going on, but you have your sights set on Medical District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Medical District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Medical District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Greenville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Medical District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Medical District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Medical District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Medical District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $81
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Medical District hotel you want, book it, and never look back. Because your great escape is ahead of you.