Hotels Near
Medical District

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking, and you save up to 60%!


Featured Medical District Hotels

Courtyard Marriott Greenville
Courtyard Marriott Greenville
3 out of 5
2225 Stantonsburg Rd, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (832 reviews)
"The windows are not sound proof. Got the worst night of sleep in a long while. Windows are old and need replaced."

Reviewed on Nov 5, 2024

Courtyard Marriott Greenville
Microtel Inn & Suites by Wyndham Greenville/University Medic
Microtel Inn & Suites by Wyndham Greenville/University Medic
2 out of 5
450 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,000 reviews)
"."

Reviewed on Nov 20, 2024

Microtel Inn & Suites by Wyndham Greenville/University Medic
Holiday Inn Greenville, an IHG Hotel
Holiday Inn Greenville, an IHG Hotel
3 out of 5
203 Greenville Blvd SW, Greenville, NC
Fully refundable
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,005 reviews)
"The hotel overall was impressive. The lobby was beautiful. The room size was also nice. I wasnt impressed with the size of the bathroom. The bathroom was very small in comparison."

Reviewed on Nov 6, 2024

Holiday Inn Greenville, an IHG Hotel
Country Inn & Suites by Radisson, Greenville, NC
Country Inn & Suites by Radisson, Greenville, NC
3 out of 5
3900 S Memorial Dr, Winterville, NC
Fully refundable
Stay at this 3-star business-friendly hotel in Winterville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (654 reviews)
"The room was fine except for the the hotel felt rundown. The bathroom was awkward to get into especially the shower because the door was really close to the toilet."

Reviewed on Nov 24, 2024

Country Inn & Suites by Radisson, Greenville, NC
Best Western Plus Suites-Greenville
Best Western Plus Suites-Greenville
2.5 out of 5
2310 Greenville Boulevard NE, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,004 reviews)
"Nice staff, but the eggs at breakfast were not that good."

Reviewed on Nov 24, 2024

Best Western Plus Suites-Greenville
Quality Inn Greenville near University
Quality Inn Greenville near University
2.5 out of 5
821 Memorial Dr, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (863 reviews)
"Room was clean,the unique"

Reviewed on Nov 22, 2024

Quality Inn Greenville near University
Holiday Inn Express Greenville, an IHG Hotel
Holiday Inn Express Greenville, an IHG Hotel
2.5 out of 5
909 Moye Blvd, Greenville, NC
Fully refundable
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (852 reviews)
"Needs to be upgraded"

Reviewed on Nov 10, 2024

Holiday Inn Express Greenville, an IHG Hotel
Baymont by Wyndham Greenville
Baymont by Wyndham Greenville
2.5 out of 5
3439 S Memorial Drive, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.2/10 (1,004 reviews)
"Toilet would not flush and wash clothes were dirty"

Reviewed on Nov 21, 2024

Baymont by Wyndham Greenville
Homewood Suites By Hilton Greenville, NC
Homewood Suites By Hilton Greenville, NC
3 out of 5
420 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star golf hotel in Greenville. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (175 reviews)
"Very safe place and clean"

Reviewed on Nov 18, 2024

Homewood Suites By Hilton Greenville, NC
Comfort Inn & Suites Greenville Near Convention Center
Comfort Inn & Suites Greenville Near Convention Center
2.5 out of 5
3212 S Memorial Dr, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (245 reviews)
"Very nice, comfortable, most importantly clean"

Reviewed on Nov 22, 2024

Comfort Inn & Suites Greenville Near Convention Center
Fairfield Inn and Suites by Marriott Washington
Fairfield Inn and Suites by Marriott Washington
2.5 out of 5
2090 West 15th Street, Washington, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Washington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (510 reviews)
Solo
"Very clean and comfortable, staff was great, friendly and helpful"

Reviewed on Nov 25, 2024

Fairfield Inn and Suites by Marriott Washington
Residence Inn by Marriott Greenville
Residence Inn by Marriott Greenville
3 out of 5
1820 W 5th St, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (363 reviews)
"Bar and breakfast"

Reviewed on Nov 3, 2024

Residence Inn by Marriott Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Medical District

Greenville is a city that has a lot going on, but you have your sights set on Medical District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Medical District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Medical District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Greenville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Medical District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Medical District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Medical District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Medical District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $68
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Medical District hotel you want, book it, and never look back. Because your great escape is ahead of you.