Hotels Near
Medical District

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Featured Medical District Hotels

Courtyard Marriott Greenville
Courtyard Marriott Greenville
3 out of 5
2225 Stantonsburg Rd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (843 reviews)
Nice hotel; opportunities for improvement.
"Concierge/receptionist was wonderful. Cleaning staff/ bistro employees were wonderful! Very accommodating and helpful. Ongoing hallway painting was an inconvenience, especially in the limited space around the elevator Bathroom was nice but water pressure in the shower needed a boost; spent too much ..."

Reviewed on Feb 1, 2025

Courtyard Marriott Greenville
Best Western Plus Suites-Greenville
Best Western Plus Suites-Greenville
2.5 out of 5
2310 Greenville Boulevard NE, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,001 reviews)
"Overall our stay was good and comfortable. There was a problem with room access keys. We had to have room keys reprogrammed 3 times out of 4 times that we left the room."

Reviewed on Feb 2, 2025

Best Western Plus Suites-Greenville
Country Inn & Suites by Radisson, Greenville, NC
Country Inn & Suites by Radisson, Greenville, NC
3 out of 5
3900 S Memorial Dr, Winterville, NC
Fully refundable
Stay at this 3-star business-friendly hotel in Winterville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (673 reviews)
"All great)"

Reviewed on Feb 2, 2025

Country Inn & Suites by Radisson, Greenville, NC
Microtel Inn & Suites by Wyndham Greenville/University Medic
Microtel Inn & Suites by Wyndham Greenville/University Medic
2 out of 5
450 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,003 reviews)
"Construction in the shared parking on a different business made a distraction, not Microtels fault"

Reviewed on Feb 4, 2025

Microtel Inn & Suites by Wyndham Greenville/University Medic
Holiday Inn Greenville, an IHG Hotel
Holiday Inn Greenville, an IHG Hotel
3 out of 5
203 Greenville Blvd SW, Greenville, NC
Fully refundable
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,002 reviews)
"All staff that I encountered were very friendly and helpful. From the lady who checked me in, housekeepers, ladies in the restaurant, to a maintenance worker. Good people make a good facility. I plan on staying there when I come back to Greenville."

Reviewed on Feb 6, 2025

Holiday Inn Greenville, an IHG Hotel
Homewood Suites By Hilton Greenville, NC
Homewood Suites By Hilton Greenville, NC
3 out of 5
420 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star golf hotel in Greenville. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (193 reviews)
"Will most certainly stay again. My family and I loved our visit to Homewood Suites👍💚"

Reviewed on Jan 27, 2025

Homewood Suites By Hilton Greenville, NC
Quality Inn Greenville near University
Quality Inn Greenville near University
2.5 out of 5
821 Memorial Dr, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (900 reviews)
"Mattress was subpar"

Reviewed on Jan 9, 2025

Quality Inn Greenville near University
Holiday Inn Express Greenville, an IHG Hotel
Holiday Inn Express Greenville, an IHG Hotel
2.5 out of 5
909 Moye Blvd, Greenville, NC
Fully refundable
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (875 reviews)
"Renovations were being done so it was in a little disarray. Bed slept very good and the room was clean. The staff were very nice and friendly."

Reviewed on Feb 4, 2025

Holiday Inn Express Greenville, an IHG Hotel
Residence Inn by Marriott Greenville
Residence Inn by Marriott Greenville
3 out of 5
1820 W 5th St, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (383 reviews)
"Loved the room layout--perfect for a family of four with teens. Only downside was the area seemed a little sketchy. Hotel itself felt very safe."

Reviewed on Feb 2, 2025

Residence Inn by Marriott Greenville
Baymont by Wyndham Greenville
Baymont by Wyndham Greenville
2.5 out of 5
3439 S Memorial Drive, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.4/10 (1,001 reviews)
"Great staff"

Reviewed on Jan 20, 2025

Baymont by Wyndham Greenville
Fairfield Inn and Suites by Marriott Washington
Fairfield Inn and Suites by Marriott Washington
2.5 out of 5
2090 West 15th Street, Washington, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Washington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (532 reviews)
We will go back!
"Very nice place- our third time and we will go back. The outside fireplace is so relaxing and rooms are very spacious."

Reviewed on Feb 4, 2025

Fairfield Inn and Suites by Marriott Washington
Fairfield Inn & Suites by Marriott Greenville
Fairfield Inn & Suites by Marriott Greenville
2.5 out of 5
908 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (387 reviews)
"Excellent all the way around! Great front desk staff. Wildlife views from my room, including nine deer at the same time one evening. Great location everything is just a few minutes away."

Reviewed on Feb 3, 2025

Fairfield Inn & Suites by Marriott Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Medical District

Greenville is a city that has a lot going on, but you have your sights set on Medical District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Medical District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Medical District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Greenville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Medical District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Medical District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Medical District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Medical District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $76
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Medical District hotel you want, book it, and never look back. Because your great escape is ahead of you.