Hotels Near
Medical District

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Featured Medical District Hotels

Courtyard Marriott Greenville
Courtyard Marriott Greenville
3 out of 5
2225 Stantonsburg Rd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (856 reviews)
"The handle was broken off in our hotel room door. No one fixed it all weekend ."

Reviewed on Mar 30, 2025

Courtyard Marriott Greenville
Microtel Inn & Suites by Wyndham Greenville/University Medic
Microtel Inn & Suites by Wyndham Greenville/University Medic
2 out of 5
450 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,001 reviews)
"N/A"

Reviewed on Apr 21, 2025

Microtel Inn & Suites by Wyndham Greenville/University Medic
Country Inn & Suites by Radisson, Greenville, NC
Country Inn & Suites by Radisson, Greenville, NC
3 out of 5
3900 S Memorial Dr, Winterville, NC
Fully refundable
Stay at this 3-star business-friendly hotel in Winterville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (715 reviews)
Excellent
"It was great I really enjoyed myself"

Reviewed on Apr 24, 2025

Country Inn & Suites by Radisson, Greenville, NC
Best Western Plus Suites-Greenville
Best Western Plus Suites-Greenville
2.5 out of 5
2310 Greenville Boulevard NE, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,000 reviews)
Not bad
"Overall was okay property. Bed was not the best (weak mattress)."

Reviewed on Apr 12, 2025

Best Western Plus Suites-Greenville
Holiday Inn Greenville by IHG
Holiday Inn Greenville by IHG
3 out of 5
203 Greenville Blvd SW, Greenville, NC
Fully refundable
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,003 reviews)
"friendly and helpful staff. safe, clean environment, good location in town."

Reviewed on Apr 24, 2025

Holiday Inn Greenville by IHG
Quality Inn Greenville near University
Quality Inn Greenville near University
2.5 out of 5
821 Memorial Dr, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (929 reviews)
"Key card wasn’t working consistently. Many tries to open the door each time."

Reviewed on Apr 5, 2025

Quality Inn Greenville near University
Holiday Inn Express Greenville by IHG
Holiday Inn Express Greenville by IHG
2.5 out of 5
909 Moye Blvd, Greenville, NC
Fully refundable
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (892 reviews)
"It would have been all 5 stars but the facility was under renovation and it was a bit chaotic in the lobby area. But the wonderful staff made up for that."

Reviewed on Mar 25, 2025

Holiday Inn Express Greenville by IHG
Homewood Suites By Hilton Greenville, NC
Homewood Suites By Hilton Greenville, NC
3 out of 5
420 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star golf hotel in Greenville. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (224 reviews)
"Customer service absolutely superb, very clean and was very close to ECU for my daughter’s tour before beginning Fall 25. This hotel will be a reoccurring option for future visits for our family!"

Reviewed on Apr 16, 2025

Homewood Suites By Hilton Greenville, NC
Comfort Inn & Suites Greenville Near Convention Center
Comfort Inn & Suites Greenville Near Convention Center
2.5 out of 5
3212 S Memorial Dr, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (287 reviews)
"It was a 1 service. I will go back again ."

Reviewed on Apr 18, 2025

Comfort Inn & Suites Greenville Near Convention Center
Fairfield Inn and Suites by Marriott Washington
Fairfield Inn and Suites by Marriott Washington
2.5 out of 5
2090 West 15th Street, Washington, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Washington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (555 reviews)
"Enjoyed stay"

Reviewed on Apr 23, 2025

Fairfield Inn and Suites by Marriott Washington
Baymont by Wyndham Greenville
Baymont by Wyndham Greenville
2.5 out of 5
3439 S Memorial Drive, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.4/10 (1,000 reviews)
Matt is the man.
"Matt at the desk was terrific. We came in later at night and he was super helpful with making it a smooth transition. Helped us get the right room for us. Thanks Matt!"

Reviewed on Apr 19, 2025

Baymont by Wyndham Greenville
Candlewood Suites Greenville NC by IHG
Candlewood Suites Greenville NC by IHG
2.5 out of 5
1055 Waterford Commons Dr, Greenville, NC
Fully refundable
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (533 reviews)
Candlewood Suites/Greenvile NC
"I liked that I could see my vehicle from my room. The parking areas are well lighted and safe. Greenville is a college town and can be busy. I have stayed here before and the staff is very friendly and helpful. Would stay again as the price is better than some of the other hotels. Convenient to Hwy ..."

Reviewed on Apr 8, 2025

Candlewood Suites Greenville NC by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Medical District

Greenville is a city that has a lot going on, but you have your sights set on Medical District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Medical District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Medical District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Greenville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Medical District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Medical District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Medical District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Medical District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $69
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Medical District hotel you want, book it, and never look back. Because your great escape is ahead of you.