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Hotels in Orangeburg

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Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

2.5 out of 5
739 Citadel Road Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,006 reviews)
The stay was wonderful

Reviewed on Mar 24, 2026

Tru by Hilton Orangeburg
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

2.5 out of 5
731 Citadel Road Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,001 reviews)
Very clean modern room

Reviewed on Mar 24, 2026

Spark by Hilton Orangeburg
Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg

2 out of 5
3620 Saint Matthews Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Stay at this motel in Orangeburg. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
Make no mistake...this is bare bones, budget accommodation. The room is spartan and decor is dated. That said, the room was clean and the staff were friendly and helpful.

Reviewed on Mar 24, 2026

Travelodge by Wyndham Orangeburg
SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg

2.5 out of 5
675 Citadel Rd Orangeburg SC
  • 13 min drive from Edisto Memorial Gardens
Stay at this hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (720 reviews)
Fabulous hotel you will enjoy you stay and love the staff

Reviewed on Mar 24, 2026

SpringHill Suites by Marriott Orangeburg
Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

2 out of 5
3608 Saint Matthews Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly motel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
6.8/10 (933 reviews)
This place really looks good in the pix but the whole property needs a ton of refurbishing.

Reviewed on Mar 23, 2026

Super 8 by Wyndham, Orangeburg
Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg

3 out of 5
663 Citadel Road Orangeburg SC
  • 10 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (739 reviews)
2 night stay for business. Safe area, friendly and helpful staff, decent continental breakfast, comfortable room. This is my second stay here.

Reviewed on Mar 20, 2026

Fairfield Inn by Marriott Orangeburg
Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg

2.5 out of 5
746 Citadel Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (589 reviews)
Horrid,

Reviewed on Mar 25, 2026

Comfort Inn & Suites Orangeburg
Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG

2.5 out of 5
118 Sleep Inn Road Orangeburg SC
  • 13 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (820 reviews)
The staff was kind and supportive, which I truly appreciated. However, the booking experience was misleading. The hotel appeared to be fully booked with only a few king-size rooms available, which led me to assume that most of my event group was staying there. In reality, it seems certain areas of ...

Reviewed on Mar 24, 2026

Holiday Inn Express & Suites Orangeburg by IHG
Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg

2.5 out of 5
749 Citadel Road Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (794 reviews)
Good all around good experience-from pulling up, in in the breakfast

Reviewed on Mar 21, 2026

Hampton Inn & Suites Orangeburg
Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg

2.5 out of 5
3671 Saint Matthews Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
6.2/10 (645 reviews)
If you don’t mine carrying all your things up stairs it will ok for you

Reviewed on Mar 15, 2026

Quality Inn & Suites Orangeburg
Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North

2.5 out of 5
3583 Saint Matthews Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
6/10 (1,000 reviews)
Poor housekeeping. Easy to fix items ignored. Low price for low quality. Ice machine room a mess. Broken down machines.

Reviewed on Mar 23, 2026

Baymont by Wyndham Orangeburg North
Sleep Inn Orangeburg

Sleep Inn Orangeburg

2.5 out of 5
3689 Saint Matthews Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
7.8/10 Good! (410 reviews)
Property needs some work. Breakfast was missing many things.

Reviewed on Mar 22, 2026

Sleep Inn Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Orangeburg

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Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Orangeburg’s 251 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $64. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Orangeburg hotel deals at the last minute.

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Frequently Asked Questions About Orangeburg hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Orangeburg?

With over 251 hotels in Orangeburg, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $64.

How to find cheap car rentals in Orangeburg?

Finding a cheap car rental deal in Orangeburg is as easy as scoring cheap hotels in Orangeburg. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.