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Hotels in Orangeburg

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Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

2.5 out of 5
739 Citadel Road Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,010 reviews)
"A coffee pot/maker in the room would be great. I didn’t want to walk to the lobby to make my hot tea I like to have before bed. Went without last night."

Reviewed on May 17, 2026

Tru by Hilton Orangeburg
Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

2 out of 5
3608 Saint Matthews Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly motel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7/10 Good! (977 reviews)
"Coffee not great okay breakfast Room was comfortable for an overnight stay"

Reviewed on May 17, 2026

Super 8 by Wyndham, Orangeburg
Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg

2 out of 5
3620 Saint Matthews Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Stay at this motel in Orangeburg. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,004 reviews)
"Bed was clean and comfortable, wifi didn’t work and was supposed to be reset, still didn’t work. Bathroom was tired looking."

Reviewed on May 14, 2026

Travelodge by Wyndham Orangeburg
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

2.5 out of 5
731 Citadel Road Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,006 reviews)
"Basic hotel, was not bad for the price."

Reviewed on May 18, 2026

Spark by Hilton Orangeburg
Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg

3 out of 5
663 Citadel Road Orangeburg SC
  • 10 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (771 reviews)
"It didn't seem as nice, compared to other Fairfield Inns or let's say what I'm use too."

Reviewed on May 18, 2026

Fairfield Inn by Marriott Orangeburg
SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg

2.5 out of 5
675 Citadel Rd Orangeburg SC
  • 13 min drive from Edisto Memorial Gardens
Stay at this hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (754 reviews)
"Very reasonable rates. Good access to the highway, restaurants and gas."

Reviewed on May 18, 2026

SpringHill Suites by Marriott Orangeburg
Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg

2.5 out of 5
3671 Saint Matthews Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
6.2/10 (663 reviews)
"It served its purpose. But very budget."

Reviewed on May 18, 2026

Quality Inn & Suites Orangeburg
Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North

2.5 out of 5
3583 Saint Matthews Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
6/10 (1,001 reviews)
"Terrible pillows."

Reviewed on May 17, 2026

Baymont by Wyndham Orangeburg North
Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg

2.5 out of 5
749 Citadel Road Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (802 reviews)
"Helpful, friendly staff. Good location"

Reviewed on May 7, 2026

Hampton Inn & Suites Orangeburg
Sleep Inn Orangeburg

Sleep Inn Orangeburg

2.5 out of 5
3689 Saint Matthews Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
7.8/10 Good! (433 reviews)
"Clean room, friendly, Stuff, absolutely terrible breakfast. It would be so simple to make it good, but dried out and cold eggs, burnt sausage, bagels with no split or way to split, a little attention to detail would go along ways."

Reviewed on May 18, 2026

Sleep Inn Orangeburg
Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg

2.5 out of 5
746 Citadel Rd Orangeburg SC
  • 12 min drive from Edisto Memorial Gardens
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (604 reviews)
"The room appeared to be missing some furniture. There was noise from the commercial washers during the night."

Reviewed on May 17, 2026

Comfort Inn & Suites Orangeburg
Orangeburg Inn & Suites

Orangeburg Inn & Suites

2 out of 5
1415 John C Calhoun Dr Orangeburg SC
  • 3 min walk from Edisto Memorial Gardens
Stay at this hotel in Orangeburg. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Edisto Memorial Gardens and Orangeburg County ...
6.4/10 (69 reviews)
"Room was clean and bed was very comfortable."

Reviewed on May 14, 2026

Orangeburg Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Orangeburg

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Orangeburg.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Orangeburg’s 254 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $61. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Orangeburg hotel deals at the last minute.

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Frequently Asked Questions About Orangeburg hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Orangeburg?

With over 254 hotels in Orangeburg, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $61.

How to find cheap car rentals in Orangeburg?

Finding a cheap car rental deal in Orangeburg is as easy as scoring cheap hotels in Orangeburg. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.