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Featured Orangeburg Family Hotels
Comfort Inn & Suites Santee
221 Britain St, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd, Orangeburg, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
Inn at Orangeburg
731 Citadel Road, Orangeburg, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Hampton Inn Santee-I-95
9060 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Best Western Plus Santee Inn
I 95 Exit 98, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Holiday Inn Express & Suites Orangeburg by IHG
118 Sleep Inn Road, Orangeburg, SC
Fully refundable
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Santee by IHG
139 Bradford Blvd, Santee, SC
Fully refundable
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
Comfort Inn & Suites
746 Citadel Rd, Orangeburg, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Super 8 by Wyndham, Orangeburg
3608 Saint Matthews Rd, Orangeburg, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
American INN of Orangeburg
610 John C Calhoun Dr, Orangeburg, SC
Stay at this hotel in Orangeburg. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions South Carolina State College Historic District ...
Econo Lodge
9112 Old 6 Highway, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Santee Cooper Country Club and Santee Outlets are ...
Days Inn by Wyndham Orangeburg
3691 Saint Matthews Rd, Orangeburg, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Orangeburg
Best Western Plus Santee Inn
I 95 Exit 98, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,002 reviews)
"Very nice property, room & bath large. Front desk ladies at check in very friendly AND they had fresh baked chocolate chip cookies 😁"
Reviewed on Apr 5, 2025
Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd, Orangeburg, SC
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
6.2/10 (1,000 reviews)
"Breakfast could have been a little better"
Reviewed on Mar 29, 2025
Inn at Orangeburg
731 Citadel Road, Orangeburg, SC
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.4/10 Good! (1,005 reviews)
"Second time staying there, awesome service"
Reviewed on Apr 6, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Orangeburg
Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd, Orangeburg, SC
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
Best Western Plus Santee Inn
I 95 Exit 98, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Comfort Inn & Suites
746 Citadel Rd, Orangeburg, SC
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Hotel Options
- Hotels with Free Parking in Orangeburg
- Hotels with a Pool in Orangeburg
- Pet-friendly Hotels in Orangeburg
- Historic Hotels in Orangeburg
- Luxury Hotels in Orangeburg
- Hotels with Hot Tubs in Orangeburg
- Hotels with an Indoor Pool in Orangeburg
- Resorts & Hotels with Spas in Orangeburg
- Hotels with smoking rooms in Orangeburg
- Adults Only Resorts & Hotels in Orangeburg
Top Points of Interests in Orangeburg
- Hotels near Edisto Memorial Gardens
- Hotels near Congaree National Park
- Hotels near Santee State Park
- Hotels near South Carolina State University
- Hotels near Santee Cooper Country Club
- Hotels near God's Acre Healing Springs
- Hotels near Santee Outlets
- Hotels near Santee National Golf Club
- Hotels near Santee National Wildlife Refuge
- Hotels near Harry Hampton Visitor Center
- Hotels near Barnwell State Park
- Hotels near St. George United Methodist Church
- Hotels near I.P. Stanback Museum & Planetarium
- Hotels near Santee Indian Mound and Fort Watson Site
- Hotels near Jennie J McMahan Library
Cities near Orangeburg
- Columbia Hotels (36.93 mi)
- Santee Hotels (21.85 mi)
- Coastal South Carolina Hotels (54.63 mi)
- Lexington Hotels (40.26 mi)
- West Columbia Hotels (36.84 mi)
- St. George Hotels (26.68 mi)
- Summerton Hotels (30.12 mi)
- Lake Marion Hotels (29.69 mi)
- Leesville Hotels (47.81 mi)
- Southeastern United States Hotels (191.02 mi)
- The Carolinas Hotels (116.83 mi)
- Eutawville Hotels (30.13 mi)
- Barnwell Hotels (34.36 mi)
- Hopkins Hotels (28.51 mi)
- Gaston Hotels (26.52 mi)
- Holly Hill Hotels (28.25 mi)
- Saint Matthews Hotels (12.76 mi)
- Vance Hotels (25.25 mi)
- Elloree Hotels (16.52 mi)
- Gadsden Hotels (24.97 mi)
Car Rentals Near Orangeburg
- Car rentals in Columbia
- Car rentals in Santee
- Car rentals in Coastal South Carolina
- Car rentals in Lexington
- Car rentals in West Columbia
- Car rentals in St. George
- Car rentals in Summerton
- Car rentals in Lake Marion
- Car rentals in Leesville
- Car rentals in Southeastern United States
- Car rentals in The Carolinas
- Car rentals in Eutawville
- Car rentals in Barnwell
- Car rentals in Hopkins
- Car rentals in Gaston
- Car rentals in Holly Hill
Top Family Hotel Destinations
- Las Vegas Family Hotels
- Arcade Family Hotels
- Branson Family Hotels
- Biloxi Family Hotels
- Ocean City Family Hotels
- Orlando Family Hotels
- Buffalo Family Hotels
- Reno Family Hotels
- Colorado Springs Family Hotels
- Phoenix Family Hotels
- Niagara Falls Family Hotels
- New York Family Hotels
- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in Orangeburg
- Tru by Hilton Orangeburg
- Super 8 by Wyndham, Orangeburg
- Travelodge by Wyndham Orangeburg
- Hampton Inn & Suites Orangeburg
- Fairfield Inn by Marriott Orangeburg
- Inn at Orangeburg
- Holiday Inn Express & Suites Orangeburg by IHG
- Baymont by Wyndham Orangeburg North
- Comfort Inn & Suites
- Days Inn by Wyndham Orangeburg
- Quality Inn & Suites
- Sleep Inn Orangeburg
- Days Inn by Wyndham Orangeburg South