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Motel 6 West Columbia, SC - Airport

Motel 6 West Columbia, SC - Airport

2 out of 5
650 Cherokee Lane West Columbia SC
  • 8 min drive from Lexington Medical Center
Book a stay at this business-friendly motel in West Columbia. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
7.6/10 Good! (492 reviews)
Super

Reviewed on Feb 7, 2026

Motel 6 West Columbia, SC - Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
  • 7 min walk from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,001 reviews)
I needed a room overnight and I needed a place with an early shuttle to the airport. This place fit the bill! Beautiful facilities, easy check in/out with very friendly and helpful staff. I requested a shuttle for 5:00 am and she was early! Again - super friendly and quick ride to the airport! Thanks ...

Reviewed on Jan 30, 2026

Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
  • 4 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (999 reviews)
The front desk manager was rude and on her cell phone the entire time

Reviewed on Feb 3, 2026

Clarion Inn Columbia Airport
TownePlace Suites Columbia West/Lexington

TownePlace Suites Columbia West/Lexington

3 out of 5
2915 SUNSET BLVD West Columbia SC
  • 7 min walk from Lexington Medical Center
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (460 reviews)
Great location near the hospital. Front desk clerk was friendly. Room was comfortable with full sized fridge.

Reviewed on Jan 31, 2026

TownePlace Suites Columbia West/Lexington
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
  • 8 min walk from Lexington Medical Center
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,008 reviews)
Clean rooms, and friendly staff

Reviewed on Feb 8, 2026

Hampton Inn Columbia-I-26 Airport
Quality Inn West Columbia - Cayce

Quality Inn West Columbia - Cayce

2.5 out of 5
3020 Charleston Hwy West Columbia SC
  • 14 min drive from Lexington Medical Center
Book a stay at this family-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (421 reviews)
Basic and affordable. Location was not my favorite, but the staff was helpful and the room was clean

Reviewed on Feb 10, 2026

Quality Inn West Columbia - Cayce
Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington

3 out of 5
122 Mathias Rd West Columbia SC
  • 6 min walk from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (365 reviews)
Space and clean

Reviewed on Feb 9, 2026

Residence Inn Columbia West/Lexington
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
  • 15 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,966 reviews)
yes

Reviewed on Feb 13, 2026

Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
  • 24 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
7.6/10 Good! (1,001 reviews)
I really enjoyed our stay , beds were very comfortable we slept like babies. Very quiet place , staff was very helpful and kind.

Reviewed on Feb 10, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

2.5 out of 5
211 Lanneau Ct Columbia SC
  • 13 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,036 reviews)
The hotel location was perfect for our trip. Our room was clean, and the staff was very courteous. However, our room was not as comfortable as previous stays we’ve had with Holiday Inn. We also thought that the breakfast could’ve been a lot better.

Reviewed on Feb 12, 2026

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
1619 Pendleton Street Columbia SC
  • 13 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.2/10 Wonderful! (1,000 reviews)
Staff were friendly, rooms were clean, pretty easy to get by and lots of stores around. Wished the shower pressure was stronger in the bathroom. Would visit again

Reviewed on Feb 3, 2026

Graduate by Hilton Columbia SC
Wyndham Garden Columbia/Ft. Jackson

Wyndham Garden Columbia/Ft. Jackson

2.5 out of 5
1539 Horseshoe Dr Columbia SC
  • 27 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,397 reviews)
None

Reviewed on Feb 11, 2026

Wyndham Garden Columbia/Ft. Jackson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in West Columbia

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $62. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great West Columbia hotel deals at the last minute.

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Frequently Asked Questions About West Columbia hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in West Columbia?

With over 1,067 hotels in West Columbia, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $62.

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