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Motel 6 West Columbia, SC - Airport

Motel 6 West Columbia, SC - Airport

2 out of 5
650 Cherokee Lane West Columbia SC
  • 8 min drive from Lexington Medical Center
Book a stay at this business-friendly motel in West Columbia. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
7.6/10 Good! (481 reviews)
Large room, clean and just right for us and two small dogs. Check in was easy and employees were nice. Would recommend.

Reviewed on Jan 8, 2026

Motel 6 West Columbia, SC - Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
  • 7 min walk from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
Spotless room Awesome staff

Reviewed on Jan 11, 2026

Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
  • 4 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,001 reviews)
Room needed painting and updating. Bed was clean, towels and bathroom were fine. TV was just sitting without a stand leaning against the wall. I’m a low maintenance traveler, it met my needs for the night.

Reviewed on Jan 2, 2026

Clarion Inn Columbia Airport
TownePlace Suites Columbia West/Lexington

TownePlace Suites Columbia West/Lexington

3 out of 5
2915 SUNSET BLVD West Columbia SC
  • 7 min walk from Lexington Medical Center
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (456 reviews)
Great stay.

Reviewed on Jan 17, 2026

TownePlace Suites Columbia West/Lexington
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
  • 8 min walk from Lexington Medical Center
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,005 reviews)
The hotel smelt clean and the staff was top tier. Bed were comfortable and I would definitely stay here again. Felt like I got more than my moneys worth.

Reviewed on Jan 18, 2026

Hampton Inn Columbia-I-26 Airport
Quality Inn West Columbia - Cayce

Quality Inn West Columbia - Cayce

2.5 out of 5
3020 Charleston Hwy West Columbia SC
  • 14 min drive from Lexington Medical Center
Book a stay at this family-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (417 reviews)
Yes

Reviewed on Jan 10, 2026

Quality Inn West Columbia - Cayce
Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington

3 out of 5
122 Mathias Rd West Columbia SC
  • 6 min walk from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (362 reviews)
The staff was very accommodating.

Reviewed on Jan 1, 2026

Residence Inn Columbia West/Lexington
Days Inn & Suites by Wyndham Columbia Airport

Days Inn & Suites by Wyndham Columbia Airport

2 out of 5
110 Branch Rd West Columbia SC
  • 9 min drive from Lexington Medical Center
Book a stay at this business-friendly motel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our ...
5.8/10 (754 reviews)
Lady at the desk was friendly and helpful. My rooms heat dis not work ao she offered to move me to another room. Room was ok, tub was stained thou

Reviewed on Dec 17, 2025

Days Inn & Suites by Wyndham Columbia Airport
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
  • 15 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,936 reviews)
Great stay!

Reviewed on Jan 20, 2026

Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
  • 24 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
7.6/10 Good! (1,004 reviews)
Staff was terrific and very accommodating. Room was clean and lovely. Shower was terrific.

Reviewed on Jan 19, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
1619 Pendleton Street Columbia SC
  • 13 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.2/10 Wonderful! (1,002 reviews)
Perfect place to stay when visiting USC

Reviewed on Jan 21, 2026

Graduate by Hilton Columbia SC
Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

2.5 out of 5
211 Lanneau Ct Columbia SC
  • 13 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,008 reviews)
Everything was so nice and clean. Bed was comfy. Staff was great

Reviewed on Jan 19, 2026

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in West Columbia

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $63. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great West Columbia hotel deals at the last minute.

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Frequently Asked Questions About West Columbia hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in West Columbia?

With over 1,074 hotels in West Columbia, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $63.

How to find cheap car rentals in West Columbia?

Finding a cheap car rental deal in West Columbia is as easy as scoring cheap hotels in West Columbia. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.