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Motel 6 West Columbia, SC - Airport

Motel 6 West Columbia, SC - Airport

2 out of 5
650 Cherokee Lane West Columbia SC
  • 8 min drive from Lexington Medical Center
Book a stay at this business-friendly motel in West Columbia. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
7.6/10 Good! (631 reviews)
"You get what you paid for. The room was huge. Plus is shower. The shower was hot and relaxing. The bed was huge. Seems kinda out the way, weird people walking around."

Reviewed on Jun 5, 2026

Motel 6 West Columbia, SC - Airport
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
  • 9 min walk from Lexington Medical Center
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"Air conditioning not good at all. Had set on the lowest setting and was hot a humid in the room the whole time. Very humid in the hallway as well. The shower sounded like it was about to take flight when it was on and the toilet ran literally all night. I’ll just pay the $150 to stay at the Hilton ..."

Reviewed on May 30, 2026

Hampton Inn Columbia-I-26 Airport
Quality Inn Columbia Airport

Quality Inn Columbia Airport

2.5 out of 5
2516 Augusta Rd West Columbia SC
  • 4 min drive from Lexington Medical Center
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.6/10 (1,003 reviews)
"This I enjoyed stay here.."

Reviewed on Jun 5, 2026

Quality Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
  • 4 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,006 reviews)
"Hotel is not clean, roaches in the breakfast area, fleas or bugs were in the room, and drug pushers and prostitutes seem to be on the backside hotel. Skip this place if you have kids or family."

Reviewed on Jun 5, 2026

Clarion Inn Columbia Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
  • 6 min walk from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,007 reviews)
"Upon checking in to our room. The staff member who was helping us tried to gaslight us into believing that all HILTON hotels do not offer a complementary breakfast. We know that this was a lie because we have been staying at many HILTON hotels during our trip, and this was the first one that didn’t ..."

Reviewed on May 28, 2026

Hilton Garden Inn Columbia Airport
Quality Inn West Columbia - Cayce

Quality Inn West Columbia - Cayce

2.5 out of 5
3020 Charleston Hwy West Columbia SC
  • 14 min drive from Lexington Medical Center
Book a stay at this family-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (478 reviews)
"Desk person was awesome! It's a nice place."

Reviewed on May 30, 2026

Quality Inn West Columbia - Cayce
Sleep Inn Columbia Airport

Sleep Inn Columbia Airport

2.5 out of 5
2208 A Edmund Hwy West Columbia SC
  • 9 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (877 reviews)
"Lamp outlets were so loose I couldn't charge my phone. I had to hold the charger in the outlet to keep a connection. But, most importantly, I booked this room at 1030pm on 5/27. I incorrectly put 5/27 instead of 5/28 for check in. While Expedia did what they could, the hotel would not refund the ..."

Reviewed on May 29, 2026

Sleep Inn Columbia Airport
Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington

3 out of 5
122 Mathias Rd West Columbia SC
  • 6 min walk from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (387 reviews)
"Enjoyed our stay! Definitely a 10 out of 10 experience!"

Reviewed on May 28, 2026

Residence Inn Columbia West/Lexington
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
  • 15 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (2,088 reviews)
"Nice hotel comfy beds great location. We will be back."

Reviewed on Jun 5, 2026

Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
  • 24 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Palmetto Performing Arts and ...
8/10 Very Good! (1,014 reviews)
"Friendly clean reasonable price"

Reviewed on Jun 5, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
  • 10 min drive from Lexington Medical Center
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and EdVenture ...
9.4/10 Exceptional! (688 reviews)
"The hotel was very very clean and the staff were extremely helpful. The free breakfast was also probably one of the better free breakfasts I’ve seen. That being said - it is a minimalist hotel. So in the room, you don’t really have any comforts. No closet very small desk and no coffee maker. Beds ..."

Reviewed on Jun 4, 2026

Tru By Hilton Columbia Downtown
Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista

3 out of 5
819 Gervais Street Columbia SC
  • 11 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,004 reviews)
"Very clean"

Reviewed on May 29, 2026

Hyatt Place Columbia/Downtown/The Vista
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in West Columbia

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in West Columbia.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of West Columbia’s 1,107 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $62. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great West Columbia hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in West Columbia. No matter your reason for visiting West Columbia, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About West Columbia hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in West Columbia for as low as $62.

How many hotels are there in West Columbia?

With over 1,107 hotels in West Columbia, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $62.

How to find cheap car rentals in West Columbia?

Finding a cheap car rental deal in West Columbia is as easy as scoring cheap hotels in West Columbia. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.