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Choose from 976 Cayce Hotel Deals

Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
  • 5 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Cayce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,004 reviews)
Clean & comfortable Great shower. Love the sitting room.

Reviewed on Mar 1, 2026

Country Inn & Suites by Radisson, Columbia Airport, SC
Courtyard by Marriott Columbia Cayce

Courtyard by Marriott Columbia Cayce

3 out of 5
1125 Fort Congaree Trail Cayce SC
  • 7 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Cayce. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (679 reviews)
Clean room, great location!

Reviewed on Mar 1, 2026

Courtyard by Marriott Columbia Cayce
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
  • 24 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,975 reviews)
Very clean room, friendly staff

Reviewed on Mar 1, 2026

Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
  • 16 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
7.8/10 Good! (1,007 reviews)
Very clean, convenient, staff was friendly, recently renovated.

Reviewed on Mar 1, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

2.5 out of 5
211 Lanneau Ct Columbia SC
  • 22 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,052 reviews)
Very nice

Reviewed on Feb 28, 2026

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
1619 Pendleton Street Columbia SC
  • 8 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,002 reviews)
The location , price, staff, and bar/food was second to none! Outstanding place, I highly recommend!

Reviewed on Feb 25, 2026

Graduate by Hilton Columbia SC
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
  • 13 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,007 reviews)
The room was clean, had everthing you could need plus somethings i brought myself, the staff was friendly and it was a great price.

Reviewed on Mar 1, 2026

Sleep Inn Columbia
Wyndham Garden Columbia/Ft. Jackson

Wyndham Garden Columbia/Ft. Jackson

2.5 out of 5
1539 Horseshoe Dr Columbia SC
  • 25 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,396 reviews)
Clean, quiet and pleasant staff

Reviewed on Feb 26, 2026

Wyndham Garden Columbia/Ft. Jackson
Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista

3.5 out of 5
1000 Lady Street Columbia SC
  • 7 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,185 reviews)
Great service location and enjoy the room

Reviewed on Feb 28, 2026

Cambria Hotel Columbia Downtown The Vista
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
  • 5 min drive from Cayce Historical Museum
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and EdVenture ...
9.4/10 Exceptional! (544 reviews)
Staff was amazing, rooms were clean. Breakfast wonderful! Restaurant could use an updated menu.

Reviewed on Mar 1, 2026

Tru By Hilton Columbia Downtown
Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista

3 out of 5
819 Gervais Street Columbia SC
  • 6 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,002 reviews)
Room was clean, bathroom not as clean as it should have been. Grouted shower surround molded, bathroom floor not clean, corners molded from shower over spray. Tub caulk line was molded. Walls/doors so thin we could hear the conversation clearly of cpl next to us AND their multi sex sessions. Had ...

Reviewed on Mar 1, 2026

Hyatt Place Columbia/Downtown/The Vista
Hyatt Place Columbia/Harbison

Hyatt Place Columbia/Harbison

3 out of 5
1130 Kinley Road Irmo SC
  • 25 min drive from Cayce Historical Museum
Book a stay at this business-friendly hotel in Irmo. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,006 reviews)
Great

Reviewed on Mar 1, 2026

Hyatt Place Columbia/Harbison
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Cayce

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $90. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Cayce hotel deals at the last minute.

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Frequently Asked Questions About Cayce hotels

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How many hotels are there in Cayce?

With over 976 hotels in Cayce, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $90.

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