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Hotels in Santee

Choose from 238 Santee Hotel Deals

Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
  • 7 min drive from Santee State Park
The price is $83 per night from Nov 10 to Nov 11
$83
includes taxes & fees
Nov 10 - Nov 11
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,288 reviews)
"An aging facility, but well-maintained."

Reviewed on Oct 31, 2024

Baymont by Wyndham Santee
Quality Inn & Suites
Quality Inn & Suites
2.5 out of 5
8929 Old Number Six Highway, Santee, SC
  • 6 min drive from Santee State Park
The price is $66 per night from Nov 18 to Nov 19
$66
includes taxes & fees
Nov 18 - Nov 19
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6/10 (299 reviews)
"Very noisy no remote in room no phone service to call office"

Reviewed on Oct 26, 2024

Quality Inn & Suites
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
  • 7 min drive from Santee State Park
The price is $150 per night from Nov 17 to Nov 18
$150
includes taxes & fees
Nov 17 - Nov 18
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,000 reviews)
"Close to 95. Friendly, efficient staff. Typical hotel breakfast, which as fine"

Reviewed on Oct 27, 2024

Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
  • 7 min drive from Santee State Park
The price is $160 per night from Nov 11 to Nov 12
$160
includes taxes & fees
Nov 11 - Nov 12
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,006 reviews)
"Property was great"

Reviewed on Nov 2, 2024

Hampton Inn Santee-I-95
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 out of 5
221 Britain St, Santee, SC
  • 7 min drive from Santee State Park
The price is $112 per night from Dec 1 to Dec 2
$112
includes taxes & fees
Dec 1 - Dec 2
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
7.8/10 Good! (902 reviews)
"Ok all was good"

Reviewed on Oct 28, 2024

Comfort Inn & Suites Santee
Holiday Inn Santee, an IHG Hotel
Holiday Inn Santee, an IHG Hotel
3 out of 5
139 Bradford Blvd, Santee, SC
  • 6 min drive from Santee State Park
The price is $138 per night from Nov 12 to Nov 13
$138
includes taxes & fees
Nov 12 - Nov 13
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (785 reviews)
"Friendly staff, comfortable beds, clean rooms"

Reviewed on Oct 13, 2024

Holiday Inn Santee, an IHG Hotel
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
  • 7 min drive from Santee State Park
The price is $127 per night from Nov 17 to Nov 18
$127
includes taxes & fees
Nov 17 - Nov 18
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.8/10 Excellent! (241 reviews)
"Comfy and clean!!"

Reviewed on Nov 2, 2024

Tru By Hilton Santee
Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2 out of 5
9117 Old Number Six Hwy, Santee, SC
  • 7 min drive from Santee State Park
The price is $67 per night from Dec 2 to Dec 3
$67
includes taxes & fees
Dec 2 - Dec 3
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
6.8/10 (541 reviews)
Travel Lodge Santee SC
"The Travel lodge in Santee last night was fine. The room was clean, the gentleman at the front desk was pleasant and the price,( though I believe for these types of motels are STILL too expensive!) given the prices of EVERYTHING these days was reasonable."

Reviewed on Oct 30, 2024

Travelodge by Wyndham Santee
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC
  • 7 min drive from Santee State Park
The price is $127 per night from Nov 11 to Nov 12
$127
includes taxes & fees
Nov 11 - Nov 12
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,003 reviews)
"It was ok for a travel stay overnight"

Reviewed on Oct 23, 2024

Best Western Plus Santee Inn
Super 8 by Wyndham Santee
Super 8 by Wyndham Santee
2 out of 5
9125 Old Highway 6, Santee, SC
  • 7 min drive from Santee State Park
The price is $83 per night from Nov 6 to Nov 7
$83
includes taxes & fees
Nov 6 - Nov 7
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee Outlets ...
6.6/10 (408 reviews)
Clean and comfortable
"Clean affordable everything in working condition"

Reviewed on Nov 1, 2024

Super 8 by Wyndham Santee
Red Roof Inn Santee
Red Roof Inn Santee
2 out of 5
9091 Old Hwy 6, Santee, SC
  • 6 min drive from Santee State Park
The price is $77 per night from Nov 6 to Nov 7
$77
includes taxes & fees
Nov 6 - Nov 7
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.4/10 (577 reviews)
"Every thing was good I would stay again"

Reviewed on Oct 25, 2024

Red Roof Inn Santee
Wyndham Vacation Resorts Lake Marion
Wyndham Vacation Resorts Lake Marion
4 out of 5
401 Bass Drive, Santee, SC
  • 6 min drive from Santee State Park
Stay at this 4-star vacation home in Santee. Enjoy free WiFi, free parking, and cable TV channels. Popular attractions Santee Cooper Country Club and Santee ...
9.4/10 Exceptional! (16 reviews)
"Beautiful environment; professional and friendly staff"

Reviewed on Oct 13, 2024

Wyndham Vacation Resorts Lake Marion
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Santee

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Santee hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santee.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santee’s 238 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $66. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Santee hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Santee. No matter your reason for visiting Santee, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Santee hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Santee for as low as $66.

How many hotels are there in Santee?

With over 238 hotels in Santee, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $66.

How to find cheap car rentals in Santee?

Finding a cheap car rental deal in Santee is as easy as scoring cheap hotels in Santee. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Santee now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Santee right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.