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Featured Santee Hotels with a Pool
Best Western Plus Santee Inn
I 95 Exit 98, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Comfort Inn & Suites Santee
221 Britain St, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
Baymont by Wyndham Santee
249 Britain Street, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Santee, an IHG Hotel
139 Bradford Blvd, Santee, SC
Fully refundable
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
Hampton Inn Santee-I-95
9060 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Econo Lodge
9112 Old 6 Highway, Santee, SC
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Santee Cooper Country Club and Santee Outlets are ...
Travelodge by Wyndham Santee
9117 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Super 8 by Wyndham Santee
9125 Old Highway 6, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee Outlets ...
Ramada by Wyndham Santee I-95
123 Mall Street, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Santee
Top Points of Interests in Santee
- Hotels near Santee State Park
- Hotels near Santee Cooper Country Club
- Hotels near Santee National Golf Club
- Hotels near Santee Outlets
- Hotels near Congaree National Park
- Hotels near Lake Marion
- Hotels near South Carolina State University
- Hotels near Santee National Wildlife Refuge
- Hotels near Wyboo Golf Club
- Hotels near Foxboro Golf Club
- Hotels near Santee Indian Mound and Fort Watson Site
- Hotels near Edisto Memorial Gardens
- Hotels near Jennie J McMahan Library
Cities near Santee
- Orangeburg Hotels (21.85 mi)
- Sumter Hotels (30.87 mi)
- Coastal South Carolina Hotels (39.54 mi)
- Manning Hotels (20.95 mi)
- St. George Hotels (21.56 mi)
- Southeastern United States Hotels (212.28 mi)
- Summerton Hotels (11.01 mi)
- The Carolinas Hotels (107.21 mi)
- Eutawville Hotels (9.84 mi)
- The South Hotels (543.71 mi)
- Ridgeville Hotels (28.75 mi)
- Cross Hotels (21.9 mi)
- Holly Hill Hotels (12.11 mi)
- Saint Matthews Hotels (21.24 mi)
- Walterboro - St. George Hotels (40.85 mi)
- Vance Hotels (4.82 mi)
- Harleyville Hotels (18.94 mi)
- Pineville Hotels (26.07 mi)
- Elloree Hotels (6.29 mi)
- Bamberg Hotels (34.78 mi)
Most Booked Hotels in Santee
- Fairfield Inn & Suites by Marriott Santee
- Hampton Inn Santee-I-95
- Holiday Inn Santee, an IHG Hotel
- Comfort Inn & Suites Santee
- Travelodge by Wyndham Santee
- Best Western Plus Santee Inn
- Red Roof Inn Santee
- Ramada by Wyndham Santee I-95
- Super 8 by Wyndham Santee
- Inn at Orangeburg
- Days Inn by Wyndham St George
Car Rentals Near Santee
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- Car rentals in Sumter
- Car rentals in Coastal South Carolina
- Car rentals in Manning
- Car rentals in St. George
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- Car rentals in Summerton
- Car rentals in The Carolinas
- Car rentals in Eutawville
- Car rentals in The South
- Car rentals in Ridgeville
- Car rentals in Cross
- Car rentals in Holly Hill
- Car rentals in Saint Matthews
- Car rentals in Walterboro - St. George
- Car rentals in Vance
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