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Santee

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Santee Flights as Low as $197

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Thu, Jun 5 - Mon, Jun 9
LGA
LaGuardia
CAE
Columbia Metropolitan
$197 Roundtrip, found 2 days ago
$197
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Jun 5 from LaGuardia to Columbia Metropolitan, returning Mon, Jun 9, priced at $197 found 2 days ago
Delta
Fri, Jun 6 - Mon, Jun 9
LGA
LaGuardia
CAE
Columbia Metropolitan
$201 Roundtrip, found 2 days ago
$201
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Jun 6 from LaGuardia to Columbia Metropolitan, returning Mon, Jun 9, priced at $201 found 2 days ago
American Airlines
Sat, Jul 12 - Tue, Jul 15
LGA
LaGuardia
CAE
Columbia Metropolitan
$209 Roundtrip, found 5 days ago
$209
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jul 12 from LaGuardia to Columbia Metropolitan, returning Tue, Jul 15, priced at $209 found 5 days ago
Delta
Sat, Jul 12 - Mon, Jul 14
LGA
LaGuardia
CAE
Columbia Metropolitan
$228 Roundtrip, found 5 days ago
$228
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Jul 12 from LaGuardia to Columbia Metropolitan, returning Mon, Jul 14, priced at $228 found 5 days ago
Bargain Flight
Sat, Apr 19 - Tue, Apr 22
PHL
Philadelphia Intl.
CAE
Columbia Metropolitan
$240 Roundtrip, found 12 hours ago
$240
Roundtrip
found 12 hours ago
Select Bargain Flight flight, departing Sat, Apr 19 from Philadelphia Intl. to Columbia Metropolitan, returning Tue, Apr 22, priced at $240 found 12 hours ago
Delta
Tue, Jul 22 - Tue, Jul 29
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jul 22 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Tue, Jul 29, priced at $249 found 1 day ago
Delta
Sat, Jun 28 - Sat, Jun 28
BWI
Baltimore Washington Intl. Thurgood Marshall
CAE
Columbia Metropolitan
$287 Roundtrip, found 1 day ago
$287
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jun 28 from Baltimore Washington Intl. Thurgood Marshall to Columbia Metropolitan, returning Sat, Jun 28, priced at $287 found 1 day ago
Delta
Wed, May 28 - Fri, May 30
DTW
Detroit Metropolitan Wayne County
CAE
Columbia Metropolitan
$290 Roundtrip, found 6 days ago
$290
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, May 28 from Detroit Metropolitan Wayne County to Columbia Metropolitan, returning Fri, May 30, priced at $290 found 6 days ago
American Airlines
Wed, Jul 16 - Sat, Jul 19
CAK
Akron-Canton
CAE
Columbia Metropolitan
$353 Roundtrip, found 17 hours ago
$353
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Wed, Jul 16 from Akron-Canton to Columbia Metropolitan, returning Sat, Jul 19, priced at $353 found 17 hours ago
American Airlines
Tue, May 6 - Sat, May 10
JFK
John F. Kennedy Intl.
CAE
Columbia Metropolitan
$353 Roundtrip, found 5 days ago
$353
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, May 6 from John F. Kennedy Intl. to Columbia Metropolitan, returning Sat, May 10, priced at $353 found 5 days ago
United
Sun, Apr 20 - Sat, Apr 26
ROC
Greater Rochester Intl.
CAE
Columbia Metropolitan
$394 Roundtrip, found 4 hours ago
$394
Roundtrip
found 4 hours ago
Select United flight, departing Sun, Apr 20 from Greater Rochester Intl. to Columbia Metropolitan, returning Sat, Apr 26, priced at $394 found 4 hours ago
American Airlines
Wed, Apr 16 - Sat, Apr 19
SBY
Salisbury - Ocean City Wicomico Regional
CAE
Columbia Metropolitan
$422 Roundtrip, found 12 hours ago
$422
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Wed, Apr 16 from Salisbury - Ocean City Wicomico Regional to Columbia Metropolitan, returning Sat, Apr 19, priced at $422 found 12 hours ago
Delta
Wed, Jun 11 - Tue, Jun 17
DFW
Dallas-Fort Worth Intl.
CAE
Columbia Metropolitan
$444 Roundtrip, found 2 days ago
$444
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Jun 11 from Dallas-Fort Worth Intl. to Columbia Metropolitan, returning Tue, Jun 17, priced at $444 found 2 days ago
American Airlines
Tue, Jun 10 - Sat, Jun 14
GRK
Killeen-Fort Hood Regional
CAE
Columbia Metropolitan
$477 Roundtrip, found 9 hours ago
$477
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Tue, Jun 10 from Killeen-Fort Hood Regional to Columbia Metropolitan, returning Sat, Jun 14, priced at $477 found 9 hours ago
Spirit Airlines
Thu, Aug 28 - Sun, Aug 31
PHL
Philadelphia Intl.
CAE
Columbia Metropolitan
$487 Roundtrip, found 4 days ago
$487
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Thu, Aug 28 from Philadelphia Intl. to Columbia Metropolitan, returning Sun, Aug 31, priced at $487 found 4 days ago
Delta
Fri, Apr 25 - Sun, Apr 27
DAL
Love Field
CAE
Columbia Metropolitan
$615 Roundtrip, found 5 days ago
$615
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Apr 25 from Love Field to Columbia Metropolitan, returning Sun, Apr 27, priced at $615 found 5 days ago

Cheap Flights to Santee

Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santee

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to Santee?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santee?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Santee.

What airport is best to fly into Santee?

When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.

How much are flights to Santee?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $197, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santee?

The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $197 right now, why wait?

Santee Flight Information
Destination airport
Columbia Metropolitan
Destination airport IATA code
CAE
Roundtrip price
$197

Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
The price is $89 per night from Apr 16 to Apr 17
$89
includes taxes & fees
Apr 16 - Apr 17
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,302 reviews)
Basic accommodation at a good price.
"Very basic at a reasonable price for folks just traveling through with pets."

Reviewed on Apr 13, 2025

Baymont by Wyndham Santee
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
The price is $122 per night from May 11 to May 12
$122
includes taxes & fees
May 11 - May 12
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (399 reviews)
"This property was clean & convenient; the staff was amazing! Breakfast was great and we had a wonderful experience overall."

Reviewed on Apr 6, 2025

Tru By Hilton Santee
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
The price is $159 per night from Apr 21 to Apr 22
$159
includes taxes & fees
Apr 21 - Apr 22
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,001 reviews)
"The check in was very easy. There are plenty Parking"

Reviewed on Apr 9, 2025

Fairfield Inn & Suites by Marriott Santee
Holiday Inn Santee by IHG
Holiday Inn Santee by IHG
3 out of 5
139 Bradford Blvd, Santee, SC
The price is $129 per night from May 13 to May 14
$129
includes taxes & fees
May 13 - May 14
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (870 reviews)
"Our room was wonderful. The staff was so very nice, both at check in and in the restaurant"

Reviewed on Apr 8, 2025

Holiday Inn Santee by IHG
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
The price is $163 per night from Apr 22 to Apr 23
$163
includes taxes & fees
Apr 22 - Apr 23
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,002 reviews)
Smiling welcome!
"Dana and Bubba were fantastic as we checked in so helpful and happy to help! Hotel was clean and close to not only 95 but lots of options for eating. AC was not as cold as we'd like but we travel with fans since we know we like to sleep in artic weather ha! Bed was okay but a little too soft for ..."

Reviewed on Apr 13, 2025

Hampton Inn Santee-I-95
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC
The price is $127 per night from May 4 to May 5
$127
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,002 reviews)
Nice hotel
"We stayed as we were driving through. Very nice hotel. I was concerned about the noisy groups of people hanging outside the hotel rooms but after a while they quieted down and the room is actually a bit sound proofed"

Reviewed on Apr 9, 2025

Best Western Plus Santee Inn
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 out of 5
221 Britain St, Santee, SC
The price is $122 per night from May 4 to May 5
$122
includes taxes & fees
May 4 - May 5
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
7.8/10 Good! (973 reviews)
"Front desk provided an excellent service. Room furniture appeared to be a bit old and worn down a bit. Bed was firm so that was very good and appreciated the upgrades to hook up electronics via electrical outlets/portals. Only disappointing item was the breakfast area and the Hot Water thermos for ..."

Reviewed on Apr 12, 2025

Comfort Inn & Suites Santee
Quality Inn & Suites
Quality Inn & Suites
2.5 out of 5
8929 Old Number Six Highway, Santee, SC
The price is $75 per night from Apr 21 to Apr 22
$75
includes taxes & fees
Apr 21 - Apr 22
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6/10 (353 reviews)
"Needs a little work."

Reviewed on Apr 11, 2025

Quality Inn & Suites
See all 271 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.