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Santee

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Santee Flights as Low as $199

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Feb 12 - Sat, Feb 15
ROC
Greater Rochester Intl.
CAE
Columbia Metropolitan
$199 Roundtrip, found 18 hours ago
$199
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Feb 12 from Greater Rochester Intl. to Columbia Metropolitan, returning Sat, Feb 15, priced at $199 found 18 hours ago
American Airlines
Wed, Feb 19 - Sat, Feb 22
DCA
Ronald Reagan Washington National
CAE
Columbia Metropolitan
$199 Roundtrip, just found
$199
Roundtrip
just found
Select American Airlines flight, departing Wed, Feb 19 from Ronald Reagan Washington National to Columbia Metropolitan, returning Sat, Feb 22, priced at $199 just found
Delta
Wed, Feb 19 - Wed, Feb 19
BOS
Logan Intl.
CAE
Columbia Metropolitan
$225 Roundtrip, found 3 days ago
$225
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Feb 19 from Logan Intl. to Columbia Metropolitan, returning Wed, Feb 19, priced at $225 found 3 days ago
Delta
Tue, Apr 15 - Sat, Apr 19
SDF
Louisville Intl.
CAE
Columbia Metropolitan
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 15 from Louisville Intl. to Columbia Metropolitan, returning Sat, Apr 19, priced at $229 found 1 day ago
Delta
Sat, Feb 15 - Tue, Feb 18
BTR
Baton Rouge Metropolitan
CAE
Columbia Metropolitan
$237 Roundtrip, found 1 day ago
$237
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Feb 15 from Baton Rouge Metropolitan to Columbia Metropolitan, returning Tue, Feb 18, priced at $237 found 1 day ago
Delta
Wed, Feb 12 - Wed, Feb 19
PVD
T.F. Green
CAE
Columbia Metropolitan
$237 Roundtrip, found 1 day ago
$237
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Feb 12 from T.F. Green to Columbia Metropolitan, returning Wed, Feb 19, priced at $237 found 1 day ago
Delta
Tue, Oct 7 - Tue, Oct 28
LIT
Clinton National Airport
CAE
Columbia Metropolitan
$249 Roundtrip, found 23 hours ago
$249
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, Oct 7 from Clinton National Airport to Columbia Metropolitan, returning Tue, Oct 28, priced at $249 found 23 hours ago
American Airlines
Sat, Aug 30 - Sun, Aug 31
STL
Lambert-St. Louis Intl.
CAE
Columbia Metropolitan
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Aug 30 from Lambert-St. Louis Intl. to Columbia Metropolitan, returning Sun, Aug 31, priced at $249 found 1 day ago
Delta
Sat, Apr 5 - Tue, Apr 8
MLI
Quad City Intl.
CAE
Columbia Metropolitan
$249 Roundtrip, found 2 days ago
$249
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Apr 5 from Quad City Intl. to Columbia Metropolitan, returning Tue, Apr 8, priced at $249 found 2 days ago
Delta
Tue, Apr 15 - Sat, Apr 19
DSM
Des Moines Intl.
CAE
Columbia Metropolitan
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 15 from Des Moines Intl. to Columbia Metropolitan, returning Sat, Apr 19, priced at $249 found 1 day ago
American Airlines
Thu, Mar 6 - Mon, Mar 10
BDL
Bradley Intl.
CAE
Columbia Metropolitan
$249 Roundtrip, found 19 hours ago
$249
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Thu, Mar 6 from Bradley Intl. to Columbia Metropolitan, returning Mon, Mar 10, priced at $249 found 19 hours ago
Delta
Thu, Feb 6 - Mon, Feb 10
RSW
Southwest Florida Intl.
CAE
Columbia Metropolitan
$254 Roundtrip, found 1 day ago
$254
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Feb 6 from Southwest Florida Intl. to Columbia Metropolitan, returning Mon, Feb 10, priced at $254 found 1 day ago
Delta
Tue, Mar 18 - Sat, Mar 22
LGA
LaGuardia
CAE
Columbia Metropolitan
$285 Roundtrip, just found
$285
Roundtrip
just found
Select Delta flight, departing Tue, Mar 18 from LaGuardia to Columbia Metropolitan, returning Sat, Mar 22, priced at $285 just found
Delta
Wed, Feb 5 - Thu, Feb 6
BWI
Baltimore Washington Intl. Thurgood Marshall
CAE
Columbia Metropolitan
$289 Roundtrip, found 5 hours ago
$289
Roundtrip
found 5 hours ago
Select Delta flight, departing Wed, Feb 5 from Baltimore Washington Intl. Thurgood Marshall to Columbia Metropolitan, returning Thu, Feb 6, priced at $289 found 5 hours ago
Delta
Tue, Jun 3 - Tue, Jun 10
PHX
Sky Harbor Intl.
CAE
Columbia Metropolitan
$314 Roundtrip, found 1 day ago
$314
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 3 from Sky Harbor Intl. to Columbia Metropolitan, returning Tue, Jun 10, priced at $314 found 1 day ago
American Airlines
Fri, Feb 21 - Tue, Feb 25
PHL
Philadelphia Intl.
CAE
Columbia Metropolitan
$350 Roundtrip, found 23 hours ago
$350
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Fri, Feb 21 from Philadelphia Intl. to Columbia Metropolitan, returning Tue, Feb 25, priced at $350 found 23 hours ago

Cheap Flights to Santee

Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santee

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to Santee?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in February, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santee?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santee.

What airport is best to fly into Santee?

When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.

How much are flights to Santee?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $199, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santee?

The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $199 right now, why wait?

Santee Flight Information
Destination airport
Columbia Metropolitan
Destination airport IATA code
CAE
Roundtrip price
$198

Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
The price is $83 per night from Jan 23 to Jan 24
$83
includes taxes & fees
Jan 23 - Jan 24
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,279 reviews)
"Highly recommend for pet owners, very convenient and super kind check in staff."

Reviewed on Jan 20, 2025

Baymont by Wyndham Santee
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
The price is $122 per night from Feb 4 to Feb 5
$122
includes taxes & fees
Feb 4 - Feb 5
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9/10 Wonderful! (304 reviews)
Nice
"Nice newer hotel just off the 95 great for a one night stop along the interstate. Staff was friendly. Rooms are small and there is noise from the highway."

Reviewed on Jan 17, 2025

Tru By Hilton Santee
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
The price is $144 per night from Feb 2 to Feb 3
$144
includes taxes & fees
Feb 2 - Feb 3
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,000 reviews)
Great place to stay.
"One of my favorite places to stay when we travel back and forth to Florida. It has everything we need. Great bathroom and shower and one of the few that actually has enough hooks."

Reviewed on Jan 17, 2025

Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
The price is $137 per night from Feb 9 to Feb 10
$137
includes taxes & fees
Feb 9 - Feb 10
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,002 reviews)
"The property and hotel was very clean and maintained. The staff was pleasant and informative. The area offered several dining options"

Reviewed on Jan 17, 2025

Hampton Inn Santee-I-95
Holiday Inn Santee, an IHG Hotel
Holiday Inn Santee, an IHG Hotel
3 out of 5
139 Bradford Blvd, Santee, SC
The price is $127 per night from Feb 9 to Feb 10
$127
includes taxes & fees
Feb 9 - Feb 10
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (828 reviews)
"Great location. Very close to many excellent restarants."

Reviewed on Jan 18, 2025

Holiday Inn Santee, an IHG Hotel
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 out of 5
221 Britain St, Santee, SC
The price is $117 per night from Feb 2 to Feb 3
$117
includes taxes & fees
Feb 2 - Feb 3
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
7.8/10 Good! (936 reviews)
Great
"Nice clean hotel, decent hot breakfast, a lot of choices locally for dinner."

Reviewed on Jan 19, 2025

Comfort Inn & Suites Santee
Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2 out of 5
9117 Old Number Six Hwy, Santee, SC
The price is $67 per night from Jan 23 to Jan 24
$67
includes taxes & fees
Jan 23 - Jan 24
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (580 reviews)
"Very nice hotel"

Reviewed on Jan 19, 2025

Travelodge by Wyndham Santee
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC
The price is $123 per night from Jan 29 to Jan 30
$123
includes taxes & fees
Jan 29 - Jan 30
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
Good, but ...
"Everything seemed good except the bathroom in room 123 as the tub would not drain properly and began filling with water as one showered. Nasty."

Reviewed on Jan 18, 2025

Best Western Plus Santee Inn
See all 261 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.