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Santee

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Santee Flights as Low as $233

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Bargain Flight
Fri, Jul 3 - Tue, Jul 21
BDL
Bradley Intl.
CAE
Columbia Metropolitan
$233 Roundtrip, found 11 hours ago
$233
Roundtrip
found 11 hours ago
Select Bargain Flight flight, departing Fri, Jul 3 from Bradley Intl. to Columbia Metropolitan, returning Tue, Jul 21, priced at $233 found 11 hours ago
Delta
Wed, Aug 5 - Mon, Aug 10
ATL
Hartsfield-Jackson Atlanta Intl.
CAE
Columbia Metropolitan
$259 Roundtrip, found 11 hours ago
$259
Roundtrip
found 11 hours ago
Select Delta flight, departing Wed, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Columbia Metropolitan, returning Mon, Aug 10, priced at $259 found 11 hours ago
American Airlines
Wed, Aug 5 - Mon, Aug 10
ATL
Hartsfield-Jackson Atlanta Intl.
CAE
Columbia Metropolitan
$279 Roundtrip, found 11 hours ago
$279
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Columbia Metropolitan, returning Mon, Aug 10, priced at $279 found 11 hours ago
American Airlines
Fri, Jul 3 - Tue, Jul 21
BDL
Bradley Intl.
CAE
Columbia Metropolitan
$293 Roundtrip, found 11 hours ago
$293
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Fri, Jul 3 from Bradley Intl. to Columbia Metropolitan, returning Tue, Jul 21, priced at $293 found 11 hours ago
Delta
Tue, Jul 14 - Tue, Jul 21
MSN
Dane County Regional
CAE
Columbia Metropolitan
$309 Roundtrip, found 16 hours ago
$309
Roundtrip
found 16 hours ago
Select Delta flight, departing Tue, Jul 14 from Dane County Regional to Columbia Metropolitan, returning Tue, Jul 21, priced at $309 found 16 hours ago
Delta
Wed, Aug 5 - Mon, Aug 10
ATL
Hartsfield-Jackson Atlanta Intl.
CAE
Columbia Metropolitan
$309 Roundtrip, found 11 hours ago
$309
Roundtrip
found 11 hours ago
Select Delta flight, departing Wed, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Columbia Metropolitan, returning Mon, Aug 10, priced at $309 found 11 hours ago
Delta
Sun, Jul 12 - Tue, Jul 21
MKE
General Mitchell Intl.
CAE
Columbia Metropolitan
$315 Roundtrip, found 16 hours ago
$315
Roundtrip
found 16 hours ago
Select Delta flight, departing Sun, Jul 12 from General Mitchell Intl. to Columbia Metropolitan, returning Tue, Jul 21, priced at $315 found 16 hours ago
Delta
Wed, Jul 8 - Tue, Jul 21
MKE
General Mitchell Intl.
CAE
Columbia Metropolitan
$323 Roundtrip, found 16 hours ago
$323
Roundtrip
found 16 hours ago
Select Delta flight, departing Wed, Jul 8 from General Mitchell Intl. to Columbia Metropolitan, returning Tue, Jul 21, priced at $323 found 16 hours ago
Delta
Sun, Jul 12 - Tue, Jul 21
MSP
Minneapolis - St. Paul Intl.
CAE
Columbia Metropolitan
$324 Roundtrip, found 16 hours ago
$324
Roundtrip
found 16 hours ago
Select Delta flight, departing Sun, Jul 12 from Minneapolis - St. Paul Intl. to Columbia Metropolitan, returning Tue, Jul 21, priced at $324 found 16 hours ago
Delta
Sun, Jul 12 - Sun, Jul 19
MSP
Minneapolis - St. Paul Intl.
CAE
Columbia Metropolitan
$326 Roundtrip, found 16 hours ago
$326
Roundtrip
found 16 hours ago
Select Delta flight, departing Sun, Jul 12 from Minneapolis - St. Paul Intl. to Columbia Metropolitan, returning Sun, Jul 19, priced at $326 found 16 hours ago
American Airlines
Wed, Aug 5 - Mon, Aug 10
ATL
Hartsfield-Jackson Atlanta Intl.
CAE
Columbia Metropolitan
$329 Roundtrip, found 11 hours ago
$329
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Columbia Metropolitan, returning Mon, Aug 10, priced at $329 found 11 hours ago
Delta
Wed, Jul 8 - Tue, Jul 21
MSN
Dane County Regional
CAE
Columbia Metropolitan
$331 Roundtrip, found 16 hours ago
$331
Roundtrip
found 16 hours ago
Select Delta flight, departing Wed, Jul 8 from Dane County Regional to Columbia Metropolitan, returning Tue, Jul 21, priced at $331 found 16 hours ago
Delta
Thu, Jul 9 - Tue, Jul 21
MKE
General Mitchell Intl.
CAE
Columbia Metropolitan
$332 Roundtrip, found 16 hours ago
$332
Roundtrip
found 16 hours ago
Select Delta flight, departing Thu, Jul 9 from General Mitchell Intl. to Columbia Metropolitan, returning Tue, Jul 21, priced at $332 found 16 hours ago
American Airlines
Sat, Jul 11 - Tue, Jul 14
STL
Lambert-St. Louis Intl.
CAE
Columbia Metropolitan
$334 Roundtrip, found 6 hours ago
$334
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Jul 11 from Lambert-St. Louis Intl. to Columbia Metropolitan, returning Tue, Jul 14, priced at $334 found 6 hours ago
American Airlines
Wed, Jul 22 - Sat, Jul 25
AUS
Austin-Bergstrom Intl.
CAE
Columbia Metropolitan
$365 Roundtrip, found 23 hours ago
$365
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Wed, Jul 22 from Austin-Bergstrom Intl. to Columbia Metropolitan, returning Sat, Jul 25, priced at $365 found 23 hours ago
American Airlines
Wed, Jul 8 - Mon, Jul 27
LAX
Los Angeles Intl.
CAE
Columbia Metropolitan
$418 Roundtrip, found 11 hours ago
$418
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Jul 8 from Los Angeles Intl. to Columbia Metropolitan, returning Mon, Jul 27, priced at $418 found 11 hours ago

Cheap Flights to Santee

Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santee

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to Santee?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santee?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Santee.

What airport is best to fly into Santee?

When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.

How much are flights to Santee?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $233, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santee?

The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $233 right now, why wait?

Santee Flight Information
Destination airport
Columbia Metropolitan
Destination airport IATA code
CAE
Roundtrip price
$232

Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,473 reviews)
"Don’t let the ratings fool you like they did me. You automatically realize you made a poor choice when you aren’t allowed in the lobby to check-in and instead have to pass id and payment through a glass window. Then you walk into the swampy bedroom and definitely know you’re going to find something ..."

Reviewed on Jun 20, 2026

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Baymont by Wyndham Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

3 out of 5
9074 Old Number Six Hwy Santee SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,004 reviews)
"Excellent and very professional. Clean and friendly"

Reviewed on Jun 22, 2026

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Fairfield Inn & Suites by Marriott Santee
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (863 reviews)
"Helpful staff, Clean room, comfy bed, nice shower, easy parking."

Reviewed on Jun 21, 2026

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Tru By Hilton Santee
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,005 reviews)
"We’ll definitely stay here again! Very attractive property, spacious room, and great breakfast. The location was very convenient. The staff was welcoming and friendly. 5 stars!"

Reviewed on Jun 22, 2026

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Best Western Plus Santee Inn
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy Santee SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,002 reviews)
"Great breakfast and wonderful staff. Try the Thai restaurant next door. Wow"

Reviewed on Jun 15, 2026

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Hampton Inn Santee-I-95
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,003 reviews)
"Nice place to stay for a family to spend a night"

Reviewed on Jun 21, 2026

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Comfort Inn & Suites Santee
Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95

2.5 out of 5
8929 Old Number Six Highway Santee SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6/10 (547 reviews)
"The floors were so dirty that my feet turned black. The toilet was broken, the bedding was very dirty. The front door was broken and wouldn’t close all the way."

Reviewed on Jun 21, 2026

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Quality Inn & Suites Santee I-95
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy Santee SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (742 reviews)
"The outside was dated but the room was clean and the bed was very comfortable!"

Reviewed on Jun 20, 2026

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Travelodge by Wyndham Santee
See all 308 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.