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Santee

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Santee Flights as Low as $239

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Tue, Apr 22 - Sat, Apr 26
ORD
O'Hare Intl.
CAE
Columbia Metropolitan
$239 Roundtrip, found 1 day ago
$239
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 22 from O'Hare Intl. to Columbia Metropolitan, returning Sat, Apr 26, priced at $239 found 1 day ago
Delta
Sat, Apr 26 - Tue, Apr 29
ORD
O'Hare Intl.
CAE
Columbia Metropolitan
$240 Roundtrip, found 1 day ago
$240
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Apr 26 from O'Hare Intl. to Columbia Metropolitan, returning Tue, Apr 29, priced at $240 found 1 day ago
Delta
Sat, Apr 26 - Tue, Apr 29
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Apr 26 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Tue, Apr 29, priced at $249 found 1 day ago
Delta
Wed, Apr 23 - Tue, Apr 29
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$250 Roundtrip, found 12 hours ago
$250
Roundtrip
found 12 hours ago
Select Delta flight, departing Wed, Apr 23 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Tue, Apr 29, priced at $250 found 12 hours ago
Delta
Mon, Apr 28 - Wed, May 7
MSP
Minneapolis - St. Paul Intl.
CAE
Columbia Metropolitan
$260 Roundtrip, found 1 day ago
$260
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Apr 28 from Minneapolis - St. Paul Intl. to Columbia Metropolitan, returning Wed, May 7, priced at $260 found 1 day ago
Delta
Tue, Apr 22 - Mon, Apr 28
ORD
O'Hare Intl.
CAE
Columbia Metropolitan
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 22 from O'Hare Intl. to Columbia Metropolitan, returning Mon, Apr 28, priced at $263 found 1 day ago
Delta
Sat, Apr 26 - Mon, Apr 28
ORD
O'Hare Intl.
CAE
Columbia Metropolitan
$264 Roundtrip, found 1 day ago
$264
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Apr 26 from O'Hare Intl. to Columbia Metropolitan, returning Mon, Apr 28, priced at $264 found 1 day ago
Delta
Tue, Apr 22 - Tue, Apr 29
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$265 Roundtrip, found 1 day ago
$265
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 22 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Tue, Apr 29, priced at $265 found 1 day ago
Delta
Wed, Apr 30 - Wed, May 7
MSP
Minneapolis - St. Paul Intl.
CAE
Columbia Metropolitan
$274 Roundtrip, found 1 day ago
$274
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Apr 30 from Minneapolis - St. Paul Intl. to Columbia Metropolitan, returning Wed, May 7, priced at $274 found 1 day ago
Delta
Wed, Mar 26 - Mon, Mar 31
LAS
Harry Reid Intl.
CAE
Columbia Metropolitan
$289 Roundtrip, found 20 hours ago
$289
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Mar 26 from Harry Reid Intl. to Columbia Metropolitan, returning Mon, Mar 31, priced at $289 found 20 hours ago
American Airlines
Mon, Apr 21 - Sat, Apr 26
ORD
O'Hare Intl.
CAE
Columbia Metropolitan
$314 Roundtrip, found 1 day ago
$314
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Apr 21 from O'Hare Intl. to Columbia Metropolitan, returning Sat, Apr 26, priced at $314 found 1 day ago
United
Tue, Mar 4 - Thu, Mar 13
MSP
Minneapolis - St. Paul Intl.
CAE
Columbia Metropolitan
$321 Roundtrip, found 3 days ago
$321
Roundtrip
found 3 days ago
Select United flight, departing Tue, Mar 4 from Minneapolis - St. Paul Intl. to Columbia Metropolitan, returning Thu, Mar 13, priced at $321 found 3 days ago
United
Thu, Apr 24 - Sun, Apr 27
ORD
O'Hare Intl.
CAE
Columbia Metropolitan
$441 Roundtrip, found 1 day ago
$441
Roundtrip
found 1 day ago
Select United flight, departing Thu, Apr 24 from O'Hare Intl. to Columbia Metropolitan, returning Sun, Apr 27, priced at $441 found 1 day ago
American Airlines
Wed, May 7 - Tue, May 13
DFW
Dallas-Fort Worth Intl.
CAE
Columbia Metropolitan
$445 Roundtrip, found 1 day ago
$445
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 7 from Dallas-Fort Worth Intl. to Columbia Metropolitan, returning Tue, May 13, priced at $445 found 1 day ago
Delta
Wed, May 7 - Tue, May 13
DAL
Love Field
CAE
Columbia Metropolitan
$455 Roundtrip, found 1 day ago
$455
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 7 from Love Field to Columbia Metropolitan, returning Tue, May 13, priced at $455 found 1 day ago
Delta
Mon, Feb 24 - Tue, Feb 25
MKE
General Mitchell Intl.
CAE
Columbia Metropolitan
$682 Roundtrip, found 20 hours ago
$682
Roundtrip
found 20 hours ago
Select Delta flight, departing Mon, Feb 24 from General Mitchell Intl. to Columbia Metropolitan, returning Tue, Feb 25, priced at $682 found 20 hours ago

Cheap Flights to Santee

Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santee

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to Santee?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santee?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santee.

What airport is best to fly into Santee?

When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.

How much are flights to Santee?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $239, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santee?

The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $239 right now, why wait?

Santee Flight Information
Destination airport
Columbia Metropolitan
Destination airport IATA code
CAE
Roundtrip price
$238

Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
The price is $89 per night from Feb 24 to Feb 25
$89
includes taxes & fees
Feb 24 - Feb 25
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,277 reviews)
"Clean comfortable, slept well."

Reviewed on Feb 18, 2025

Baymont by Wyndham Santee
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
The price is $149 per night from Mar 3 to Mar 4
$149
includes taxes & fees
Mar 3 - Mar 4
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,003 reviews)
"Very nice hotel. The breakfast was excellent."

Reviewed on Feb 21, 2025

Fairfield Inn & Suites by Marriott Santee
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
The price is $103 per night from Mar 16 to Mar 17
$103
includes taxes & fees
Mar 16 - Mar 17
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9/10 Wonderful! (342 reviews)
"Good clean facilities and breakfast was very good"

Reviewed on Feb 21, 2025

Tru By Hilton Santee
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
The price is $146 per night from Mar 12 to Mar 13
$146
includes taxes & fees
Mar 12 - Mar 13
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,002 reviews)
"Great!"

Reviewed on Feb 22, 2025

Hampton Inn Santee-I-95
Holiday Inn Santee, an IHG Hotel
Holiday Inn Santee, an IHG Hotel
3 out of 5
139 Bradford Blvd, Santee, SC
The price is $117 per night from Feb 26 to Feb 27
$117
includes taxes & fees
Feb 26 - Feb 27
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (839 reviews)
"Loved the friendliness of the staff and the open airiness of the lobby. Shower curtain did not fit the shower."

Reviewed on Feb 18, 2025

Holiday Inn Santee, an IHG Hotel
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC
The price is $123 per night from Mar 2 to Mar 3
$123
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
"All is fine."

Reviewed on Feb 16, 2025

Best Western Plus Santee Inn
Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2 out of 5
9117 Old Number Six Hwy, Santee, SC
The price is $67 per night from Feb 24 to Feb 25
$67
includes taxes & fees
Feb 24 - Feb 25
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (590 reviews)
Good Deal!
"It's clean, quiet, and very reasonably priced. What more do you need?"

Reviewed on Feb 5, 2025

Travelodge by Wyndham Santee
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 out of 5
221 Britain St, Santee, SC
The price is $122 per night from Mar 2 to Mar 3
$122
includes taxes & fees
Mar 2 - Mar 3
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
7.8/10 Good! (943 reviews)
"The Front Desk workers are friendly and effecient!"

Reviewed on Feb 14, 2025

Comfort Inn & Suites Santee
See all 262 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.