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Santee

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Santee Flights as Low as $195

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Fri, Jun 6 - Mon, Jun 9
LGA
LaGuardia
CAE
Columbia Metropolitan
$195 Roundtrip, found 1 day ago
$195
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Fri, Jun 6 from LaGuardia to Columbia Metropolitan, returning Mon, Jun 9, priced at $195 found 1 day ago
Delta
Thu, Jun 5 - Mon, Jun 9
LGA
LaGuardia
CAE
Columbia Metropolitan
$201 Roundtrip, found 5 days ago
$201
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, Jun 5 from LaGuardia to Columbia Metropolitan, returning Mon, Jun 9, priced at $201 found 5 days ago
American Airlines
Sat, Aug 16 - Tue, Aug 19
LGA
LaGuardia
CAE
Columbia Metropolitan
$209 Roundtrip, found 5 days ago
$209
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Aug 16 from LaGuardia to Columbia Metropolitan, returning Tue, Aug 19, priced at $209 found 5 days ago
Delta
Fri, Jun 6 - Mon, Jun 9
LGA
LaGuardia
CAE
Columbia Metropolitan
$213 Roundtrip, found 1 day ago
$213
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Jun 6 from LaGuardia to Columbia Metropolitan, returning Mon, Jun 9, priced at $213 found 1 day ago
Delta
Wed, Jul 2 - Fri, Jul 4
BOS
Logan Intl.
CAE
Columbia Metropolitan
$220 Roundtrip, found 1 day ago
$220
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jul 2 from Logan Intl. to Columbia Metropolitan, returning Fri, Jul 4, priced at $220 found 1 day ago
Delta
Fri, Jul 25 - Sun, Jul 27
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$225 Roundtrip, found 1 day ago
$225
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Jul 25 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Sun, Jul 27, priced at $225 found 1 day ago
Delta
Wed, Jul 2 - Tue, Jul 8
BOS
Logan Intl.
CAE
Columbia Metropolitan
$227 Roundtrip, found 3 days ago
$227
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Jul 2 from Logan Intl. to Columbia Metropolitan, returning Tue, Jul 8, priced at $227 found 3 days ago
United
Sat, May 24 - Mon, May 26
DEN
Denver Intl.
CAE
Columbia Metropolitan
$257 Roundtrip, found 20 hours ago
$257
Roundtrip
found 20 hours ago
Select United flight, departing Sat, May 24 from Denver Intl. to Columbia Metropolitan, returning Mon, May 26, priced at $257 found 20 hours ago
American Airlines
Wed, May 7 - Tue, May 13
STL
Lambert-St. Louis Intl.
CAE
Columbia Metropolitan
$274 Roundtrip, found 5 days ago
$274
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, May 7 from Lambert-St. Louis Intl. to Columbia Metropolitan, returning Tue, May 13, priced at $274 found 5 days ago
Delta
Wed, Jul 30 - Tue, Aug 5
PDX
Portland Intl.
CAE
Columbia Metropolitan
$319 Roundtrip, found 4 days ago
$319
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Jul 30 from Portland Intl. to Columbia Metropolitan, returning Tue, Aug 5, priced at $319 found 4 days ago
Delta
Sun, May 18 - Sun, May 25
JAX
Jacksonville Intl.
CAE
Columbia Metropolitan
$365 Roundtrip, found 22 hours ago
$365
Roundtrip
found 22 hours ago
Select Delta flight, departing Sun, May 18 from Jacksonville Intl. to Columbia Metropolitan, returning Sun, May 25, priced at $365 found 22 hours ago
American Airlines
Fri, May 23 - Sat, May 24
JFK
John F. Kennedy Intl.
CAE
Columbia Metropolitan
$390 Roundtrip, found 5 days ago
$390
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, May 23 from John F. Kennedy Intl. to Columbia Metropolitan, returning Sat, May 24, priced at $390 found 5 days ago
Delta
Fri, May 9 - Mon, May 12
ABQ
Albuquerque Intl. Sunport
CAE
Columbia Metropolitan
$414 Roundtrip, found 17 hours ago
$414
Roundtrip
found 17 hours ago
Select Delta flight, departing Fri, May 9 from Albuquerque Intl. Sunport to Columbia Metropolitan, returning Mon, May 12, priced at $414 found 17 hours ago
Delta
Thu, May 8 - Thu, May 8
BHM
Birmingham Intl.
CAE
Columbia Metropolitan
$769 Roundtrip, found 1 day ago
$769
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, May 8 from Birmingham Intl. to Columbia Metropolitan, returning Thu, May 8, priced at $769 found 1 day ago
American Airlines
Thu, Nov 13 - Thu, Nov 20
PSC
Tri-Cities
CAE
Columbia Metropolitan
$795 Roundtrip, found 20 hours ago
$795
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Thu, Nov 13 from Tri-Cities to Columbia Metropolitan, returning Thu, Nov 20, priced at $795 found 20 hours ago
Alaska Airlines
Thu, Nov 13 - Thu, Nov 20
PSC
Tri-Cities
CAE
Columbia Metropolitan
$912 Roundtrip, found 20 hours ago
$912
Roundtrip
found 20 hours ago
Select Alaska Airlines flight, departing Thu, Nov 13 from Tri-Cities to Columbia Metropolitan, returning Thu, Nov 20, priced at $912 found 20 hours ago

Cheap Flights to Santee

Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santee

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to Santee?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santee?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santee.

What airport is best to fly into Santee?

When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.

How much are flights to Santee?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $195, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santee?

The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $195 right now, why wait?

Santee Flight Information
Destination airport
Columbia Metropolitan
Destination airport IATA code
CAE
Roundtrip price
$195

Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
The price is $89 per night from May 6 to May 7
$89
includes taxes & fees
May 6 - May 7
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,297 reviews)
"Great staff comfy stay"

Reviewed on May 3, 2025

Baymont by Wyndham Santee
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
The price is $122 per night from May 18 to May 19
$122
includes taxes & fees
May 18 - May 19
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (405 reviews)
Clean, convenient and new.
"We stopped over on our way to Florida. The hotel was new and very clean. The location was very convenient with many services close by. We were traveling with our dogs and they were welcomed for an additional fee. Breakfast was generous and tasty. The rooms are not carpeted which is great for cleanliness ..."

Reviewed on May 1, 2025

Tru By Hilton Santee
Holiday Inn Santee by IHG
Holiday Inn Santee by IHG
3 out of 5
139 Bradford Blvd, Santee, SC
The price is $145 per night from Jun 3 to Jun 4
$145
includes taxes & fees
Jun 3 - Jun 4
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (878 reviews)
"Friendly staff"

Reviewed on May 2, 2025

Holiday Inn Santee by IHG
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
The price is $159 per night from May 13 to May 14
$159
includes taxes & fees
May 13 - May 14
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,007 reviews)
"It was good; staff helpful. One area for improvement is bathroom door in the disabled room opens toward room door. If guest in room itself and has a walker then you have to close bathroom door, walk past then open door. It would be helpful for door to open other way and could then be accessed without ..."

Reviewed on Apr 30, 2025

Fairfield Inn & Suites by Marriott Santee
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 out of 5
221 Britain St, Santee, SC
The price is $122 per night from May 13 to May 14
$122
includes taxes & fees
May 13 - May 14
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (983 reviews)
"Front desk was service was great! Lobby was comfortable and clean."

Reviewed on Apr 27, 2025

Comfort Inn & Suites Santee
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
The price is $151 per night from May 25 to May 26
$151
includes taxes & fees
May 25 - May 26
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,000 reviews)
"V good stay Comfortable beds and good with pet offering cookies and poop bags 2 free waters Would stay again"

Reviewed on Apr 29, 2025

Hampton Inn Santee-I-95
Quality Inn & Suites
Quality Inn & Suites
2.5 out of 5
8929 Old Number Six Highway, Santee, SC
The price is $70 per night from May 12 to May 13
$70
includes taxes & fees
May 12 - May 13
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6/10 (364 reviews)
"…."

Reviewed on Apr 27, 2025

Quality Inn & Suites
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC
The price is $127 per night from May 18 to May 19
$127
includes taxes & fees
May 18 - May 19
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,002 reviews)
Nice stop.
"Great location. Traveling with dogs and they provide a great place for potty break and walks. Very clean and beds were comfortable. Bathroom was clean , could use a update . Breakfast was nice. Staff was friendly."

Reviewed on May 1, 2025

Best Western Plus Santee Inn
See all 280 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.