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Santee

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Santee Flights as Low as $198

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Wed, Oct 15 - Sat, Oct 18
JFK
John F. Kennedy Intl.
CAE
Columbia Metropolitan
$198 Roundtrip, found 10 hours ago
$198
Roundtrip
found 10 hours ago
Select Delta flight, departing Wed, Oct 15 from John F. Kennedy Intl. to Columbia Metropolitan, returning Sat, Oct 18, priced at $198 found 10 hours ago
Spirit Airlines
Sun, Aug 24 - Sun, Aug 31
IAH
George Bush Intercontinental
CAE
Columbia Metropolitan
$199 Roundtrip, found 2 days ago
$199
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Sun, Aug 24 from George Bush Intercontinental to Columbia Metropolitan, returning Sun, Aug 31, priced at $199 found 2 days ago
Spirit Airlines
Sat, Aug 23 - Sun, Aug 31
IAH
George Bush Intercontinental
CAE
Columbia Metropolitan
$203 Roundtrip, found 2 days ago
$203
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Sat, Aug 23 from George Bush Intercontinental to Columbia Metropolitan, returning Sun, Aug 31, priced at $203 found 2 days ago
Bargain Flight
Tue, Sep 30 - Sat, Oct 4
BOS
Logan Intl.
CAE
Columbia Metropolitan
$205 Roundtrip, found 4 hours ago
$205
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Tue, Sep 30 from Logan Intl. to Columbia Metropolitan, returning Sat, Oct 4, priced at $205 found 4 hours ago
Delta
Tue, Sep 30 - Sat, Oct 4
BOS
Logan Intl.
CAE
Columbia Metropolitan
$210 Roundtrip, found 4 hours ago
$210
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Sep 30 from Logan Intl. to Columbia Metropolitan, returning Sat, Oct 4, priced at $210 found 4 hours ago
American Airlines
Tue, Sep 30 - Sat, Oct 4
BOS
Logan Intl.
CAE
Columbia Metropolitan
$211 Roundtrip, found 4 hours ago
$211
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Sep 30 from Logan Intl. to Columbia Metropolitan, returning Sat, Oct 4, priced at $211 found 4 hours ago
Delta
Tue, Sep 30 - Wed, Oct 1
BOS
Logan Intl.
CAE
Columbia Metropolitan
$217 Roundtrip, found 4 hours ago
$217
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Sep 30 from Logan Intl. to Columbia Metropolitan, returning Wed, Oct 1, priced at $217 found 4 hours ago
Delta
Wed, Oct 15 - Mon, Oct 20
JFK
John F. Kennedy Intl.
CAE
Columbia Metropolitan
$219 Roundtrip, found 10 hours ago
$219
Roundtrip
found 10 hours ago
Select Delta flight, departing Wed, Oct 15 from John F. Kennedy Intl. to Columbia Metropolitan, returning Mon, Oct 20, priced at $219 found 10 hours ago
United
Wed, Oct 1 - Sat, Oct 4
BOS
Logan Intl.
CAE
Columbia Metropolitan
$219 Roundtrip, found 1 day ago
$219
Roundtrip
found 1 day ago
Select United flight, departing Wed, Oct 1 from Logan Intl. to Columbia Metropolitan, returning Sat, Oct 4, priced at $219 found 1 day ago
United
Tue, Sep 30 - Sat, Oct 4
BOS
Logan Intl.
CAE
Columbia Metropolitan
$222 Roundtrip, found 4 hours ago
$222
Roundtrip
found 4 hours ago
Select United flight, departing Tue, Sep 30 from Logan Intl. to Columbia Metropolitan, returning Sat, Oct 4, priced at $222 found 4 hours ago
Spirit Airlines
Tue, Aug 26 - Fri, Aug 29
IAH
George Bush Intercontinental
CAE
Columbia Metropolitan
$223 Roundtrip, found 1 day ago
$223
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Tue, Aug 26 from George Bush Intercontinental to Columbia Metropolitan, returning Fri, Aug 29, priced at $223 found 1 day ago
United
Wed, Oct 1 - Sat, Oct 4
BOS
Logan Intl.
CAE
Columbia Metropolitan
$225 Roundtrip, found 1 day ago
$225
Roundtrip
found 1 day ago
Select United flight, departing Wed, Oct 1 from Logan Intl. to Columbia Metropolitan, returning Sat, Oct 4, priced at $225 found 1 day ago
Delta
Wed, Oct 8 - Tue, Oct 14
BWI
Baltimore Washington Intl. Thurgood Marshall
CAE
Columbia Metropolitan
$257 Roundtrip, found 3 days ago
$257
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Oct 8 from Baltimore Washington Intl. Thurgood Marshall to Columbia Metropolitan, returning Tue, Oct 14, priced at $257 found 3 days ago
Delta
Sat, Aug 30 - Wed, Sep 3
BOI
Boise
CAE
Columbia Metropolitan
$294 Roundtrip, just found
$294
Roundtrip
just found
Select Delta flight, departing Sat, Aug 30 from Boise to Columbia Metropolitan, returning Wed, Sep 3, priced at $294 just found
Spirit Airlines
Fri, Sep 5 - Mon, Sep 8
SJU
Luis Munoz Marin Intl.
CAE
Columbia Metropolitan
$416 Roundtrip, found 2 days ago
$416
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Fri, Sep 5 from Luis Munoz Marin Intl. to Columbia Metropolitan, returning Mon, Sep 8, priced at $416 found 2 days ago
Alaska Airlines
Wed, Aug 27 - Mon, Sep 8
BOI
Boise
CAE
Columbia Metropolitan
$462 Roundtrip, just found
$462
Roundtrip
just found
Select Alaska Airlines flight, departing Wed, Aug 27 from Boise to Columbia Metropolitan, returning Mon, Sep 8, priced at $462 just found

Cheap Flights to Santee

Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santee

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to Santee?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santee?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Santee.

What airport is best to fly into Santee?

When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.

How much are flights to Santee?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $198, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santee?

The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $198 right now, why wait?

Santee Flight Information
Destination airport
Columbia Metropolitan
Destination airport IATA code
CAE
Roundtrip price
$197

Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,328 reviews)
"Clean, nice beds, able to regulate room temperature effectively, adequate plug ins for tech devices and had a decent shower. Two problems very low water pressure for bathroom sink and had difficulty in turning off shower as the main shower control is in the way for turning the faucet completely ..."

Reviewed on Jul 27, 2025

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Baymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (489 reviews)
My short getaway
"Although my stay was a short amount of time, I Njoy it a lot. I did have an opportunity to get in the pool, which I Njoy. Next time much longer time to stay."

Reviewed on Jul 25, 2025

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Tru By Hilton Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,013 reviews)
"Nice staff and breakfast, new clean facilities."

Reviewed on Jul 25, 2025

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Fairfield Inn & Suites by Marriott Santee
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
7.8/10 Good! (1,011 reviews)
"It was ok good enough for the night. Breakfast is good"

Reviewed on Jul 20, 2025

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Comfort Inn & Suites Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,010 reviews)
"Great staff - Friendly- Dog Friendly- Safe Area"

Reviewed on Jul 26, 2025

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Hampton Inn Santee-I-95
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd, Santee, SC
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (917 reviews)
"Great"

Reviewed on Jul 14, 2025

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Holiday Inn Santee by IHG
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
8929 Old Number Six Highway, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
5.8/10 (414 reviews)
"It was much better than the last time we tried to stay there. They are making progress renovating it."

Reviewed on Jun 23, 2025

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Quality Inn & Suites
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,005 reviews)
V
"Everything was great. Fast check-in, room was clean, breakfast choices were all good."

Reviewed on Jul 26, 2025

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Best Western Plus Santee Inn
See all 292 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.