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Cheap Flights to Santee

Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santee

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to Santee?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santee?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Santee.

What airport is best to fly into Santee?

When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.

How much are flights to Santee?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santee?

The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Santee Flight Information
Destination airport
Santee
Destination airport IATA code
CAE

Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,371 reviews)
"The room seemed clean, but it was very dated. Standard waffle iron cereal, pastry breakfast."

Reviewed on Oct 18, 2025

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Baymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (566 reviews)
"Excellent room"

Reviewed on Oct 17, 2025

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Tru By Hilton Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,006 reviews)
"Nice place. Very friendly staff. Clean rooms. Beds were really hard. Breakfast was good."

Reviewed on Oct 14, 2025

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Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,002 reviews)
"This is the second time we've stayed here and everything is as it should be. It seems like a newer hotel, so things are nice and fresh. The Staff at the desk and at breakfast were very friendly. We will most likely stay here again."

Reviewed on Oct 9, 2025

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Hampton Inn Santee-I-95
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,003 reviews)
"The room and Hotel was clean."

Reviewed on Oct 12, 2025

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Comfort Inn & Suites Santee
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd, Santee, SC
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (955 reviews)
"Great hotel w"

Reviewed on Oct 12, 2025

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Holiday Inn Santee by IHG
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
8929 Old Number Six Highway, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
5.8/10 (443 reviews)
Second time staying here
"The room floor was very dirty the flooring was lamantin and easy to clean I feel that it had not been cleaned in a long time other than this taking into account price and age of the hotel room was good bottoms of my socks were very dirty from walking on this floor I understand how hotels go I worked ..."

Reviewed on Oct 14, 2025

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Quality Inn & Suites
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,006 reviews)
"Cockroach in our bathroom discovered soon upon our entry. The room was located next to the pool area. Furniture is dated, but showed signs of former elegance. Breakfast was excellent. Much broader selection than at most other places. We have seen the woman who oversees the breakfast area on another ..."

Reviewed on Oct 13, 2025

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Best Western Plus Santee Inn
See all 290 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.