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Spa Resort Hotels in Santee

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Featured Santee Resorts & Hotels with Spas

Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2 out of 5
9117 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Travelodge by Wyndham Santee
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Hampton Inn Santee-I-95
Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Baymont by Wyndham Santee
Rodeway Inn Santee I-95
Rodeway Inn Santee I-95
2 out of 5
123 Mall Street, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Rodeway Inn Santee I-95
Holiday Inn Santee, an IHG Hotel
Holiday Inn Santee, an IHG Hotel
3 out of 5
139 Bradford Blvd, Santee, SC
Fully refundable
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in ...
Holiday Inn Santee, an IHG Hotel
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Santee Cooper Country Club and Santee Outlets ...
Tru By Hilton Santee
Red Roof Inn Santee
Red Roof Inn Santee
2 out of 5
9091 Old Hwy 6, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular ...
Red Roof Inn Santee
Super 8 by Wyndham Santee
Super 8 by Wyndham Santee
2 out of 5
9125 Old Highway 6, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular attractions ...
Super 8 by Wyndham Santee
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Best Western Plus Santee Inn
See all 232 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.